Effectiveness of Boiling Method Using Aquadest Solvent in Oolong Tea Extraction Producing Mangenese Particle as a Contrast Media on Magnetic Resonance Cholangiopancreatography (MRCP)

Magnetic Resonance Cholangiography (MRCP) examines the pancreas and ductus billiaris using magnetic resonance imaging with a negative contrast media administered orally. Oolong tea is possible to be an alternative of an oral negative contrast media due to its manganese contained. This study will elaborate on the best method of oolong tea extraction to get the best mangenese substance and its capability to suppress inevitable organs. This is an experimental study with various methods of extraction, which are the maceration method with ethanol solvent, maceration method with aquadest solvent, and boiling method. The whole process includes collecting and preparing plant materials, sample identification, sample processing, extraction, and extract characterization. The manganese level is checked with Atomic Absorption Spectroscopy (AAS) followed by scanning the extracted oolong tea in bottles and MRCP scanning examination. Results showed that manganese level with three different extraction methods is maceration method with ethanol is 1.23 mg/dl, maceration method with aquadest solvent is 0.82 mg/dl, and the extraction using the boiling method with aquadest solvent 0.94 mg/dl, and manufactured tea 1.40 mg/dl respectively. Scanning the extracted oolong tea in bottles showed that the best suppression is on the bottle, which contains extracted oolong tea using a boiling method with aquadest solvent. The image enhancement on MRCP showed that biliary trees are all enhanced using all the extraction methods; however, the best suppression for the stomach and duodenum is using the boiling method with aquadest solvent. The best choice for oolong tea extraction to get the best image to enhance and maximum suppression for disturbing organs is the boiling method with aquadest solvent. For the oolong tea, oral media contrast is to consider the level of manganese substance and its capability to suppress the disturbing organ to provide the best image for MRCP

Assessment of Available Manganese in Milk by Using fodders Grown in Long-Term Wastewater Irrigated Soil

Heavy metals are considered as most important contaminations due to industrialization of countries and an influence on its existence in soil, plant and milk. A study was carried out to check manganese content in soil, forage and milk at three sites of city Jhang, Punjab, Pakistan. All samples (milk, soil, water, fodder plants and ground water) were analyzed for manganese by Atomic Absorption Spectrophotometer. Different health indices were also studied to check Mn flow in food chain. Level of Mn in samples was found within acceptable limits. Manganese level was higher in soil samples collected from Site-III than other sites. Manganese showed higher value (2.595 to 10.402 mg/kg) in soil than other samples. Fodders were found to accumulate manganese from 0.008 to 0.022 mg/kg. Manganese concentration was found to be 0.1482 to 1.241 mg/L, 0.164 to 0.9708 mg/L in water and milk, respectively. BCF and PLI values for manganese were also found to be less than 1. Estimated daily intake (EDI) and THQ of manganese are found within permissible limits in milk of cows feeding on fodders irrigated with wastewater and ground water. So, use of wastewater for irrigation purpose should be properly checked due to possible toxic effects.

Effectiveness of caporite to reduce concentration of iron and mangan in Ciliwung river water as raw water PDAM

The water of the Ciliwung river used as raw water for PDAM Depok contains iron and manganese, which levels were quite high and exceeded the quality standard. The purposes of the research are to determine the effectiveness of caporite to reduce levels of iron and manganese to reach levels that meet the standards of Government Regulation Number 82 of 2001. The sample used in this study was the water of the Ciliwung river used as a source of raw water for PDAM Depok with two different water treatment plant (WTP) locations, location 1 in Legong WTP and location 2 in Citayam WTP. Raw water was taken using a submersible water pump located at the bottom of the Ciliwung river. The analytical method used as a reference for determining iron levels was based on the FerroZine Rapid Liquid Method 1970, and for manganese levels was based on 1- (2-Pyridylazo) -2-Naphthol PAN Method 1977, both methods using the Spectrophotometric method. The results showed that iron and manganese levels were quite high, exceeding the standards of Government Regulation No.82 of 2001 with a maximum standard of iron content is 0.3 mg/L, and a maximum standard of manganese level is 0.1 mg/L. After adding a certain dose of chlorine to Ciliwung river water in the Legong and Citayam WTPs, it was found that chlorine effectively reduced Fe and Mn levels because it was able to reduce levels up to 80% and meet the quality standards.Keywords: Caporite, Iron, Manganese, Ciliwung River, RegulationABSTRAKEfektivitas kaporit untuk menurunkan kadar besi dan mangan dalam air sungai Ciliwung sebagai air baku PDAMAir sungai Ciliwung yang digunakan sebagai air baku PDAM Depok terdapat zat besi dan mangan dengan kadarnya cukup tinggi serta melebihi ambang baku mutu. Tujuan penelitian ini untuk mengetahui efektivitas kaporit dalam menurunkan kadar besi dan mangan sehingga memenuhi standar baku mutu Peraturan Pemerintah Nomor 82 Tahun 2001 untuk kelas 1. Sampel air yang digunakan dalam penelitian ini diambil dari 2 titik lokasi Instalasi Pengolahan Air (IPA) yang berbeda, yaitu dari IPA Legong dan IPA Citayam. Sampel air baku diambil dengan menggunakan pompa air submersible (pompa celup) yang berada di dasar sungai Ciliwung. Penelitian dilakukan dengan eksperimen jar test di laboratorium. Metode analisis untuk menentukan kadar besi mengacu pada FerroZine Rapid Liquid Method tahun 1970 dan mangan berdasarkan 1-(2-Pyridylazo)-2-Napthol PAN Method tahun 1977 dengan menggunakan metode Spektrofotometri. Hasil penelitian menunjukan kadar besi dan mangan yang cukup tinggi hingga melebihi standar yang telah ditetapkan dalam PP No.82 Tahun 2001 dengan kadar Fe maksimal 0,3 mg/L dan kadar Mn maksimal 0,1 mg/L. Setelah dilakukan penambahan bahan kimia kaporit ke dalam sampel air sungai Ciliwung dari IPA Legong dan Citayam, dengan dosis 10 mg/L untuk penurunan Fe dan 30 mg/L untuk penurunan Mn dapat efektif menurunkan konsentrasi Fe dan Mn hingga 80%, dan memenuhi standar baku mutu yang digunakan.Kata Kunci: Kaporit, Besi, Mangan, Sungai Ciliwung, Baku Mutu

Is there any association between manganese level and schizophrenia? - a descriptive review

Introduction: Manganese has a role in the membrane transport systems, synthesis of protein, vitamin C, and vitamins B, catalysis of hematopoiesis, regulation of the endocrine, immune system, blood sugar, reproduction, digestion, and blood coagulation. Furthermore, the level of manganese concentrations in human body appears to affect the occurrence of schizophrenia. The aim of this study was to search for relationships between the manganese level and the onset of schizophrenia.Material and methods: A descriptive review was performed based on a literature search on Medline and Google scholar from 2003 to 2020, using keywords: schizophrenia, manganese, Mn. The included studies were meta-analyses, case-control studies, and cohort studies that examined differences in manganese concentrations in patients with schizophrenia and healthy controls.Result: Eight studies were selected for the review, with one reporting elevated levels of manganese, two showing no significant differences, and the rest including two meta-analyses stating lower manganese concentrations in patients with schizophrenia in comparison with controls.Conclusion: In most of the researched studies, manganese concentrations in patients with schizophrenia were lower than in control groups, but not all of them reached the same conclusions. The relationship between manganese levels and schizophrenia must be further investigated.

Levels of Serum Zinc and Manganese among Post-Menopausal Patients with Thyroid Dysfunction

The objective of this study is to shed more light on the role of trace metals and their mode of action in hyperthyroidism and hypothyroidism in Post-Menopausal Patients. The content of the trace elements Zinc and Manganese (Zn, and Mn) in the serum of patients was determined. Forty patients with hyperthyroidism and hypothyroidism were participated in this study. Serum zinc and manganese were determined using flame atomic absorption spectrophotometer technique. The study showed that serum zinc and manganese levels of hyperthyroidism patients were significantly lower (p<0.05). While a significant increase in serum manganese level with decrease serum zinc levels in patients with hypothyroidism (p<0.05). The present study confirmed a significant change in the levels of serum Zn, Mn in hyperthyroidism and hypothyroidism among Post-Menopausal patients and these changes may be related to pathophysiology of thyroid disease.

Kulit Pisang Kepok (Musa paradisiaca L.) untuk Menurunkan Kadar Mangan Air Sumur

Water is an essential requirement. Part of Indonesian people still using well as the source of water Resulting from the increased of human activity and industries, the well water maybe contaminated by manganese ( Mn). That is needed processing to make well water usefull for mankind. One of the type for processing water is the absorbtion methode .Banana shell was kitchen waste and the dried of Kepok Banana (Musa paradisiaca) Shell was used as adsobent to reduce Manganese level in water. This study aimed to determine the reduce of Manganese level in water. This research was real experiment pretest and posttest study design with a control group. Persulfate research instruments colorimetric and spectrophotometric measurements. The addition of the dose banana shell were 0,06 ; 0,07; 0,08; 0,09; 0,1 gram . By those dose cumulatively decreased to 0; 21,84; 32,34; 44,56; and 52,92%. The Manganese maximum reduced by 0,1 gram dried banana shell in 100 cc well water in 30 minutes. Stastically , the significan value was 0,000 less than 0,05(α) , it was meant that the variety dose of dried Kepok banana shell influence to decrease Manganese level in water. These decreased way can be used as an alternative to increase the water quality. Keywords: manganese, kepok banana shell Abstrak: Air merupakan kebutuhan utama bagi masyarakat Indonesia. Sumber air yang banyak digunakan adalah air tanah, yaitu air sumur. Diakibatkan dari meningkatnya aktivitas manusia dan industri, air sumur dapat tercemar mangan (Mn). Untuk dapat menjadikan air sumur sebagai sumber air bersih, perlu dilakukan pengolahan. Proses pengolahan ini dapat dilakukan dengan metode adsorpsi. Bahan yang dipakai dapat dimanfaatkan dari limbah dapur rumah tangga seperti kulit pisang kepok (Musa paradisiaca L.) sebagai bahan adsorben. Penelitian bertujuan untuk mengetahui penurunan kadar mangan dalam air dengan menggunakan kulit pisang kepok (Musa paradisiaca L.) yang dikeringkan. Penelitian ini berjenis eksperimen sebenarnya rancangan penelitian Pretest dan Posttest dengan Kelompok Kontrol. Instrumen penelitian persulfat kolorimetri dan pengukuran secara spektrofotometri. Secara kumulatif penurunan kadar mangan dari hasil penambahan kulit pisang kepok dengan dosis 0 gram, 0,06 gram, 0,07 gram, 0,08 gram, 0,09 gram, dan 0,1 gram berturut-turut adalah sebesar 0%, 21,845%, 32,637%, 37,337%, 44,560%, dan 52,916%. Hasil maksimum dari reaksi tersebut yaitu kadar mangan dalam air berkurang hingga 52,916% untuk dosis 0,1 gram/100 ml air selama 30 menit. Pada hasil statistik didapatkan nilai signifikasi p=0,000 (α 0,05) atau ada pengaruh dosis kulit pisang kepok terhadap penurunan kadar mangan pada air sumur. Penurunan kadar mangan melalui cara ini dapat dijadikan alternatif untuk mendapatkan air bersih dari air sumur. Kata kunci: Mangan (Mn), Kulit Pisang Kepok