Levels of Serum Zinc and Manganese among Post-Menopausal Patients with Thyroid Dysfunction

2016 ◽  
Vol 5 (02) ◽  
pp. 4821
Author(s):  
Sharique Ahmad* ◽  
Saeeda Wasim
Keyword(s):  
Thyroid Dysfunction ◽  
Serum Zinc ◽  
Flame Atomic Absorption ◽  
Flame Atomic Absorption Spectrophotometer ◽  
Serum Zn ◽  
Zinc Levels ◽  
Post Menopausal ◽  
Manganese Level ◽  
Serum Zinc Levels

The objective of this study is to shed more light on the role of trace metals and their mode of action in hyperthyroidism and hypothyroidism in Post-Menopausal Patients. The content of the trace elements Zinc and Manganese (Zn, and Mn) in the serum of patients was determined. Forty patients with hyperthyroidism and hypothyroidism were participated in this study. Serum zinc and manganese were determined using flame atomic absorption spectrophotometer technique. The study showed that serum zinc and manganese levels of hyperthyroidism patients were significantly lower (p<0.05). While a significant increase in serum manganese level with decrease serum zinc levels in patients with hypothyroidism (p<0.05).  The present study confirmed a significant change in the levels of serum Zn, Mn in hyperthyroidism and hypothyroidism among Post-Menopausal patients and these changes may be related to pathophysiology of thyroid disease.

scholarly journals Association between Serum Zinc and hs-CRP Concentrations in Different Metabolic Syndrome Phenotypes

2021 ◽  
Author(s):  
Susan Darroudi ◽  
Batool Tayefi ◽  
Habibollah Esmaily ◽  
Fatemeh Sadabadi ◽  
Hamideh Moalemzadeh Haghighi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Serum Zinc ◽  
Heart Association ◽  
Flame Atomic Absorption ◽  
Increased Risk ◽  
Serum Zn ◽  
Hs Crp ◽  
Zinc Levels ◽  
The Relationship ◽  
Serum Zinc Levels

Abstract Background: Metabolic syndrome (MetS) is associated with an increased risk of cardiovascular disease and all-cause mortality. Zinc (Zn) is an essential trace element for the synthesis, storage, and release of insulin. The relationship between serum Zn and MetS is controversial. In this study we have evaluated whether serum Zn levels are associated with hsCRP level according to MetS phenotypes. Method: A total of 9493 individuals (3768 men and 5635 women) were recruited as part of the Mashhad Stroke and Heart Association Disorder (MASHAD) study. We measured the concentration of serum Zn by flame atomic absorption (Varian AA240FS) and we divided the subjects into quartile of serum Zn. We used SPSS version 18 statistical analyses for all. GraphPad Prism 6 for figures was used.Results: In this study there were significant differences between quartiles of Zn according to sex. The results showed that the level of serum hs-CRP were higher in subjects with metabolic syndrome who also had a serum Zn >95 µg/dl. In subjects with serum Zn <70 µg/dl, an increase in serum hs-CRP was associated with an increased risk of MetS by 2.2%, 1.022(CI: 1.01-1.034). Moreover, among subjects in the first, second and third quartiles of serum Zn, some phenotypes of metabolic syndrome (WHB, WHT, WTG, WTB, WHBG, WHTG, and WTBG) were associated with a risk of increasing hs-CRP level (p< 0.05). Conclusion: Serum hs-CRP concentrations were related to MetS phenotypes. This relationship was modified by serum Zn level. According to the number of MetS components serum Zn levels decreased as the number of MetS component increased, and low serum zinc levels (Q1) showed an overall greater prevalence of MetS.

Role of serum zinc levels in simple febrile convulsions in children

2019 ◽  
Vol 9 (1) ◽  
pp. 36-38
Author(s):  
S W Srikanth ◽  
◽  
Sharanagouda Patil ◽  
Rachapudi Venkata Anusha ◽  
◽  
...  
Keyword(s):  
Serum Zinc ◽  
Febrile Convulsions ◽  
Zinc Levels ◽  
Serum Zinc Levels

scholarly journals Zinc Intake, Zinc Serum Levels, and Intelligence in School Children in Rural Areas

2021 ◽  
Vol 9 (E) ◽  
pp. 394-397
Author(s):  
Rostika Flora ◽  
Nur Alam Fajar ◽  
Fatmalina Febri ◽  
Indah Yuliana ◽  
Yuliarti Yuliarti ◽  
...  
Keyword(s):  
Zinc Deficiency ◽  
School Children ◽  
Significant Relationship ◽  
Rural Areas ◽  
Serum Zinc ◽  
Zinc Intake ◽  
Serum Zn ◽  
Zinc Levels ◽  
Serum Zinc Levels ◽  
Low Serum

BACKGROUND: Children in rural areas are susceptible to zinc deficiency. Zinc deficiency in children can affect cognitive function in children. Zinc plays a role in cellular function and critical brain growth processes, including cell replication, DNA and RNA synthesis, and the release of neurotransmitters. AIM: This study aimed to analyze the condition of zinc deficiency and its relationship with the level of intelligence in children in rural areas. METHODS: The study design was cross-sectional, with a sample of 44 elementary school children aged 9–12 years taken randomly. Blood was drawn to measure serum Zn-levels, and serum Zn-levels were measured using Colorimetric Assay Kit (E-BC-K137). Zinc intake data were obtained from the food recall form, which was carried out 3 × 24 h. The level of intelligence is measured by the Culture Fair Intelligence Test method. The sample characteristics data obtained through a questionnaire. Furthermore, the data were analyzed using the Chi-square test. RESULTS: About 84.2% of children with insufficient zinc intake had low serum Zn-levels. There was a significant relationship between zinc intake and serum zinc levels (p = 0.026; PR = 4.293). Children with low serum zinc levels of 96.5% have intelligence levels below average. There was a significant relationship between serum zinc levels and intelligence level as well (p = 0.001; PR = 24,500). CONCLUSION: Zinc deficiency in children is characterized by low serum Zn-levels. Low serum Zn-level is caused by low zinc intake, thus children with low serum Zn-levels are at risk of having intelligence level below average. Therefore, health education about the importance of zinc intake in children should be given to parents, so that the incidence of zinc deficiency in children can be reduced.

scholarly journals Changes in Serum Zinc Levels in Relation to Blood Pressure During Anaesthesia

2003 ◽  
Vol 40 (138) ◽  
pp. 67-71
Author(s):  
H K Garg ◽  
P Agrawal ◽  
S Haleem
Keyword(s):  
Venous Blood ◽  
Serum Zinc ◽  
Study Groups ◽  
Surgical Operation ◽  
Defence Mechanisms ◽  
Serum Zn ◽  
Zinc Levels ◽  
Serum Zinc Levels ◽  
Age And Sex ◽  
Maximum Rise

Fifty age and sex matched patients admitted for surgical operation, were divided intonormotensive (control) and hypertensive (study) groups. Systolic and diastolic bloodpressures were recorded preoperatively, 10 min after intubation, at max-increase ofBP and 24 hours postoperatively. 5 ml. venous blood samples were drawn at thesetime periods, and serum zinc was also estimated. Control Gp (normotensive) subjectrecorded fall (p < 0.001) in serum Zn 10 min after intubation (n = 18) and max. Riseof BP (n = 7), Twelve subjects in study Gp recorded a rise in serum Zn at max. Increaseof BP (p < 0.01). The pattern in normotensives points towards mobilization of zinc,while in hypertensives, homeostatic, defence mechanisms appear to resist mobilizationof serum Zn till maximum rise in BP occurs, indicating hormonal and other influenceson serum Zn levels during anaesthesia.Key Words: Serum Zinc, Systolic BP, Diastolic BP, Anaesthesia

scholarly journals Assessment of Serum Zinc Levels of Patients with Thalassemia Compared to Their Siblings

Anemia ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Mohamed El Missiry ◽  
Mohamed Hamed Hussein ◽  
Sadaf Khalid ◽  
Naila Yaqub ◽  
Sarah Khan ◽  
...  
Keyword(s):  
Serum Zinc ◽  
Zn Deficiency ◽  
Median Serum ◽  
Significant Difference ◽  
Serum Zn ◽  
Z Scores ◽  
Absolute Lymphocyte Counts ◽  
Zinc Levels ◽  
Serum Zinc Levels ◽  
Height For Age

Zinc (Zn) is essential for appropriate growth and proper immune function, both of which may be impaired in thalassemia children. Factors that can affect serum Zn levels in these patients may be related to their disease or treatment or nutritional causes. We assessed the serum Zn levels of children with thalassemia paired with a sibling. Zn levels were obtained from 30 children in Islamabad, Pakistan. Serum Zn levels and anthropometric data measures were compared among siblings. Thalassemia patients’ median age was 4.5 years (range 1–10.6 years) and siblings was 7.8 years (range 1.1–17 years). The median serum Zn levels for both groups were within normal range: 100 μg/dL (10 μg/dL–297 μg/dL) for patients and 92 μg/dL (13 μg/dL–212 μg/dL) for siblings. There was no significant difference between the two groups. Patients’ serum Zn values correlated positively with their corresponding siblings (r=0.635,P<0.001). There were no correlations between patients’ Zn levels, height for age Z-scores, serum ferritin levels, chelation, or blood counts (including both total leukocyte and absolute lymphocyte counts). Patients’ serum Zn values correlated with their siblings’ values. In this study, patients with thalassemia do not seem to have disease-related Zn deficiency.

scholarly journals A comparison of serum zinc levels in melasma and non-melasma patients: a preliminary study of thyroid dysfunction

2020 ◽  
Vol 29 (2) ◽  
Author(s):  
Indina Sastrini Sekarnesia ◽  
Irma Bernadette S. Sitohang ◽  
Triana Agustin ◽  
Wismandari Wisnu ◽  
Aida S. D. Hoemardani
Keyword(s):  
Thyroid Dysfunction ◽  
Serum Zinc ◽  
Preliminary Study ◽  
Zinc Levels ◽  
Serum Zinc Levels

scholarly journals A comparative study of serum zinc levels in children with febrile seizures and children with fever without seizures in an urban referral hospital

2018 ◽  
Vol 5 (3) ◽  
pp. 977 ◽  
Author(s):  
P. Sampathkumar ◽  
K. Suresh Kannan
Keyword(s):  
Zinc Deficiency ◽  
Serum Zinc ◽  
Febrile Seizures ◽  
Serum Levels ◽  
Predisposing Factor ◽  
Study Population ◽  
Zinc Levels ◽  
Group Serum ◽  
Serum Zinc Levels

Background: Febrile seizures are the most common cause of convulsions in children. However, the exact underlying etiology and the pathophysiological mechanisms are yet to be established. Various theories have been put forward regarding the role of trace elements as predisposing factors in causing the convulsions. Among them, Zinc is the most interesting trace element whose role in diarrhea and pneumonia is well proven. This study was done to know the correlation between zinc and febrile seizures, to estimate the serum levels of zinc in children with simple and complex febrile seizures and compare it with children with fever without seizures and to compare the levels of zinc in simple and complex febrile seizures.Methods: The study was conducted for a period of 6 months in the Department of Paediatrics, GMKMCH, and Salem. The study population included the children between 6 months to 6 years. During the study period 60 consecutive children with simple febrile seizures, 40 consecutive children with complex febrile seizures and 200 consecutive children with fever without seizures formed the study group. Serum zinc levels were measured in the three groups by using the calorimetric method.Results: The serum zinc levels were found to be low in 65% and 75% of children with simple and complex febrile seizures respectively. Only 20% of febrile children without convulsions had low zinc levels. Thus, a positive correlation was found between zinc deficiency and febrile convulsions.Conclusions: This study establishes a definite relationship between zinc deficiency and febrile seizures thereby substantiating zinc as an important predisposing factor in febrile seizures.

scholarly journals Serum zinc levels in children with upper respiratory tract infection in the age 2-12years in Pakistan.

2020 ◽  
Vol 27 (09) ◽  
pp. 1927-1930
Author(s):  
Firdos Jabeen ◽  
Muhammad Fayaz Khan Burki ◽  
Muhammad Naeem Burki ◽  
Nawab Zada Khan ◽  
Abdus Salam ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Serum Zinc ◽  
Zinc Level ◽  
Upper Respiratory Tract ◽  
Serum Zinc Level ◽  
Serum Zn ◽  
Upper Respiratory ◽  
Zinc Levels ◽  
Serum Zinc Levels

Objectives: The persuasive evidence shows that proper Zinc (Zn) nutrition is important for human health. Hence an attempt was made to evaluate the serum Zn levels in children suffering from high respiratory infection in children aged 2-12years in Pakistan. Study Design: Case-control study. Setting: Jinnah Medical Teaching Hospital Peshawar with the collaboration of National Physical Standard Laboratory PCSIR Islamabad. Period: March 2017 to March 2019. Material & Methods: 60 children who were suffering from upper respiratory tract infection and were admitted in the Paediatric ward of Jinnah medical teaching hospital Peshawar. 60 normal controls of the same genders with an age range 2-12 years were selected for this study. Serum zinc levels were measured with atomic absorption spectrophotometer (AAS). Results: The serum zinc level was found to be low in 80% patients. Mean ±SD of serum zinc were 58.9 ±2.70µg/dl in diseased group and 100 ±2.22µg/dl in controls respectively. In patients serum zinc level was significantly lower than that of healthy controls (P<0.001). Conclusion: We may conclude that Zinc deficiency may play a role in the pathogenesis of upper tract respiratory infection since most diseased children have low serum Zn level.

scholarly journals Association between Reduced Serum Zinc and Diastolic Dysfunction in Maintenance Hemodialysis Patients

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2077
Author(s):  
Jiun-Chi Huang ◽  
Ya-Chin Huang ◽  
Pei-Yu Wu ◽  
Wen-Hsien Lee ◽  
Yi-Chun Tsai ◽  
...  
Keyword(s):  
Diastolic Dysfunction ◽  
Left Atrial Volume ◽  
Serum Zinc ◽  
Zinc Level ◽  
Volume Index ◽  
Serum Zinc Level ◽  
Lower Serum ◽  
Echocardiographic Parameters ◽  
Zinc Levels ◽  
Serum Zinc Levels

Diastolic dysfunction is an emerging challenge among hemodialysis (HD) patients, and the associations between serum zinc with echocardiographic parameters and diastolic function remain uncertain. A total of 185 maintenance HD patients were stratified by the tertiles of serum zinc level to compare their clinical characteristics and echocardiography. Correlations of serum zinc levels with echocardiographic parameters were examined using Pearson’s analysis. Univariate and multivariate logistic regression analyses were performed to investigate the determinants of E/e’ ratio >15 and left atrial volume index (LAVI) > 34 mL/m2, both indicators of diastolic dysfunction. Patients belonging to the first tertile of serum zinc level had a significantly higher E/e’ ratio and LAVI. Serum zinc levels were negatively correlated with E (r = −0.204, p = 0.005), E/e’ ratio (r = −0.217, p = 0.003), and LAVI (r = −0.197, p = 0.007). In a multivariate analysis, older age, diabetes, coronary artery disease, and lower serum zinc levels (OR = 0.974, 95% CI = 0.950–0.999, p = 0.039) were significantly associated with E/e’ ratio >15. Furthermore, diabetes and lower serum zinc levels (OR = 0.978, 95% CI = 0.958–0.999, p = 0.041) were significantly associated with LAVI >34 mL/m2. Reduced serum zinc level was significantly associated with diastolic dysfunction among HD patients. Further prospective studies are warranted to investigate whether zinc supplementation can attenuate cardiac dysfunction in maintenance HD patients.

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