type ii pks
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2021 ◽  
Vol 143 (7) ◽  
pp. 2962-2969
Author(s):  
Jie Zhang ◽  
Satoshi Yuzawa ◽  
Wei Li Thong ◽  
Tetsuro Shinada ◽  
Makoto Nishiyama ◽  
...  
Keyword(s):  
Type Ii ◽  

2021 ◽  
Vol 85 (1) ◽  
pp. 148-153
Author(s):  
Mitsuki Seo ◽  
Danyao Du ◽  
Yohei Katsuyama ◽  
Ryo Katsuta ◽  
Arata Yajima ◽  
...  

Abstract Ishigamide was isolated as a metabolite of a recombinant strain of Streptomyces sp. MSC090213JE08 and its unsaturated fatty acid moiety has been confirmed in vitro to be synthesized by a type II PKS. Biosynthesis of such a highly reduced polyketide by a type II PKS is worthy of note. However, absolute configuration of ishigamide remained unknown. (R)-Ishigamide was synthesized enantioselectively employing Stille coupling and Wittig reaction between three units, vinyl iodide, stannyldienal, and Wittig salt. Stereochemistry of natural ishigamide was determined to be R by chiral HPLC analysis comparing with the synthesized standard.


2019 ◽  
Vol 141 (42) ◽  
pp. 16615-16623 ◽  
Author(s):  
Gina L. C. Grammbitter ◽  
Maximilian Schmalhofer ◽  
Kudratullah Karimi ◽  
Yi-Ming Shi ◽  
Tim A. Schöner ◽  
...  
Keyword(s):  
Type Ii ◽  

2019 ◽  
Vol 10 (18) ◽  
pp. 4839-4846 ◽  
Author(s):  
Jing Shi ◽  
Cheng Li Liu ◽  
Bo Zhang ◽  
Wen Jie Guo ◽  
Jiapeng Zhu ◽  
...  

Genome mining targeting unique type II PKS and NRPS led to the identification of a novel class of glycopeptides named kitacinnamycins.


RSC Advances ◽  
2019 ◽  
Vol 9 (64) ◽  
pp. 37376-37383
Author(s):  
Ling-Li Liu ◽  
Hong-Fei Liu ◽  
Hua-Hua Gao ◽  
Zheng-Zhong Yang ◽  
Xiao-Lan Feng ◽  
...  

The ethyl acetate extract from the liquid fermentation of S. caelestis Aw99c exhibited high and broad antifungal activities against plant pathogenic fungi.


2019 ◽  
Vol 17 (9) ◽  
pp. 2370-2378 ◽  
Author(s):  
Taro Ozaki ◽  
Ryosuke Sugiyama ◽  
Morito Shimomura ◽  
Shinichi Nishimura ◽  
Shumpei Asamizu ◽  
...  

The new subfamily of type II PKS gene cluster is responsible for biosynthesis of structurally distinct streptoaminals (STAMs) and 5-alkyl-1,2,3,4-tetrahydroquinolines (5aTHQs).


2018 ◽  
Vol 83 (4) ◽  
pp. 1876-1890 ◽  
Author(s):  
Andrew W. Robertson ◽  
Jeanna M. MacLeod ◽  
Logan W. MacIntyre ◽  
Stephanie. M. Forget ◽  
Steven R. Hall ◽  
...  

2016 ◽  
Vol 7 ◽  
Author(s):  
Joseph Selvin ◽  
Ganesan Sathiyanarayanan ◽  
Anuj N. Lipton ◽  
Naif Abdullah Al-Dhabi ◽  
Mariadhas Valan Arasu ◽  
...  

ChemBioChem ◽  
2011 ◽  
Vol 13 (2) ◽  
pp. 224-230 ◽  
Author(s):  
Xiaohui Yan ◽  
Katharina Probst ◽  
Anton Linnenbrink ◽  
Moritz Arnold ◽  
Thomas Paululat ◽  
...  

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