Tissue vitamin E concentrations after single injection of α-tocopherol in pigs

1994 ◽  
Vol 74 (3) ◽  
pp. 579-581 ◽  
Author(s):  
T. R. Batra ◽  
M. Hidiroglou
Keyword(s):  
Vitamin E ◽  
Intramuscular Injection ◽  
Neck Muscle ◽  
Tocopherol Concentration ◽  
Treatment Groups ◽  
Hip Muscle ◽  
Single Intramuscular Injection ◽  
Muscle Concentration ◽  
Effect Of Treatment ◽  
Injection Effect

Forty pigs were randomly assigned to one of the four treatment groups: control, 500 IU, 1500 IU, and 2500 IU of vitamin E given as a single intramuscular injection. Out of 40 pigs, 20 were slaughtered at day 3 and the remaining 20 at day 7 after injection. Effect of treatment was significant (P < 0.05) for vitamin E concentrations in all tissues. The effect of time of slaughter after the injection was significant (P < 0.05) for spleen, liver, kidney, lung, hip muscle and adrenal, while the interaction of treatment with time was significant (P < 0.05) for most of the tissues except adipose tissue and neck muscle. Concentration of α-tocopherol in all tissues increased with increased dose of injection. In most tissues, α-tocopherol concentration was higher at 3 d than at 7 d after injection. By 7 d, levels had dropped significantly but were still much higher than control levels. Intramuscular injection of vitamin E in pigs resulted in significant differences in tissue α-tocopherol concentrations. Key words: Vitamin E, tissues, pigs

Comparison of α -tocopherol acetate preparations given as single intraperitoneal or subcutaneous doses for increasing plasma and liver α -tocopherol in sheep fed a low vitamin E diet

1996 ◽  
Vol 36 (4) ◽  
pp. 421 ◽  
Author(s):  
GM Smith ◽  
JM Fry ◽  
KF Ilett
Keyword(s):  
Vitamin E ◽  
Effective Means ◽  
Plasma Concentrations ◽  
The Other ◽  
Maximum Plasma ◽  
Time Curve ◽  
Tocopherol Concentration ◽  
Treatment Groups ◽  
Tocopherol Acetate ◽  
Aqueous Method

This experiment examined the efficacy of a single dose of �-tocopherol acetate (2000 IU) in either an aqueous or oily formulation, given as an intraperitoneal (i.p.) or subcutaneous (s.c.) injection or orally as an aqueous formulation, at raising a-tocopherol concentrations in blood plasma and liver of young sheep with low vitamin E. Maximum plasma concentrations (Cmax) were greatest in sheep supplemented by the s.c.-aqueous method or orally (4.83 and 3.49 mg/L respectively). These values were 3.0-5.7 times the C, values of the other treatment groups. Also, the time taken to reach Cmax (Tmax) was far shorter in these 2 treatments than in the other treatments (Tmax values were 0.70 and 0.65 days respectively). Tmax values were greatest for the oily formulation (42 and 73 days for the i.p. and S.C. injections, respectively). The area under the plasma a-tocopherol concentration-time curve (AUC(0-85d)), was greatest for the s.c.-aqueous group (median of 2066 mg.h/L). Six of the sheep in the i.p.-aqueous group had AUC(0-85d) values similar to the controls whereas the rest were similar to the s.c.-aqueous group. Plasma �-tocopherol acetate was only consistently detected in sheep in the s.c.-aqueous group (Cmax of 25.25 � 3.14 mg/L and Tmax of 0.24 � 0.03 days). Pharmacokinetic modelling of the plasma data obtained from sheep in the s.c.-aqueous group was helpful in understanding the factors which controlled the appearance and disappearance rates of plasma �-tocopherol in this group. In contrast to plasma data, liver concentrations of �-tocopherol at days 24 and 57 were greatest in sheep supplemented by the i.p.-oily method. The s.c.-aqueous was the second most effective method at raising concentrations in the liver. The results suggest that supplementation by s.c. injection of an aqueous formulation may be an effective means of administering vitamin E to sheep.

Vitamin E and selenium in milk of ewes

1994 ◽  
Vol 74 (3) ◽  
pp. 567-569 ◽  
Author(s):  
A. Meneses ◽  
T. R. Batra ◽  
M. Hidiroglou
Keyword(s):  
Vitamin E ◽  
Key Words ◽  
Intramuscular Injection ◽  
Sodium Selenite ◽  
Selenium Supplementation ◽  
Treatment Groups ◽  
Milk Samples ◽  
Whole Milk ◽  
Key Words Vitamin E

Eighteen ewes were randomly assigned to one of three treatment groups: control, injected vitamin E, and injected selenium, with the objective of evaluating the effect of these treatments on the concentration of vitamin E and selenium in the milk. Vitamin E injections were given by intramuscular injection at the rate of 2000 IU per ewe at lambing and at 6 wk after lambing. Selenium supplementation was given by intramuscular injection at the rate of 12 mg sodium selenite at lambing and at 5 wk after lambing. Milk samples from all ewes in the three groups were collected for determination of vitamin E and selenium 0, 1, 2, 7, 14, 21, 28, 35, 42, 49, and 56 d after lambing. Ewes injected with vitamin E or selenium at lambing increased the concentration of these nutrients in milk during the first 14 d of lactation; as a result, increased amounts of vitamin E and selenium were available to suckling lambs during their early days of life. Milk levels of selenium but not vitamin E were increased by subsequent injection of selenium or vitamin E, respectively. It was also observed that colostrum contained higher concentrations of both vitamin E and selenium than did whole milk. Key words: Vitamin E, Se, milk, ewes

COMPARAISON DE DIVERSES METHODES DE CASTRATION ET DE STERILISATION DES AGNEAUX: I. INFLUENCE DE CES METHODES SUR LA CROISSANCE, L’EFFICIENCE ALIMENTAIRE, LE RENDEMENT A L’AHATTAGE ET LA RENTABILITE

1971 ◽  
Vol 51 (3) ◽  
pp. 579-589 ◽  
Author(s):  
J. M. BAILLARGEON ◽  
J. P. LEMAY ◽  
W. B. HOLTMANN ◽  
L. A. CHARETTE
Keyword(s):  
Feed Efficiency ◽  
Intramuscular Injection ◽  
Cadmium Chloride ◽  
Complete Removal ◽  
Chemical Methods ◽  
Treatment Groups ◽  
Dressing Percentage ◽  
Breeding Groups ◽  
Physical And Chemical ◽  
Daily Gain

An experiment was conducted to compare various physical and chemical methods of castration of lambs at 15 and 60 days of age. Their effects on body growth, feed efficiency, dressing percentage and profitability were studied. At birth 100 lambs were divided among the 16 different treatments according to sex and the following breeding groups: Suffolk, North Country Cheviot, two-breed cross and three-breed cross. The different methods of castration were: complete removal of the testicles, Burdizzo, elastrator and partial castration. The sterilization methods consisted of intramuscular, intratesticular and intraveinous injection of cadmium chloride. All lambs were weaned at 30 days of age and placed in individual pens. They were subjected to similar environmental conditions and shipped to slaughter at approximately 45 kg body weight. Significant differences were observed among breeds, sexes and the various castration methods for daily gain, feed efficiency, days required to reach market and profitability. Age at castration did not have any important effect ort the variables measured. Superior gains, feed efficiency and profitability were observed for the partially castrated group, for the lambs that received an intramuscular injection of cadmium chloride and for the non-castrated males. All treatment groups involving males were superior to the females for the characters studied except for dressing percentage.

scholarly journals 43 Effect of Mushroom Probiotic (Coriolus Versicolor) on Galectin Gene Secretion in Goat Blood

2020 ◽  
Vol 98 (Supplement_2) ◽  
pp. 71-72
Author(s):  
Kingsley E Ekwemalor ◽  
Emmanuel K Asiamah ◽  
Sarah Adjei-Fremah ◽  
Eboghoye ElukaOkoludoh ◽  
Mulumebet Worku
Keyword(s):  
Plasma Protein ◽  
Cold Water ◽  
Cold Treatment ◽  
Coriolus Versicolor ◽  
Control Group ◽  
Plasma Protein Concentration ◽  
Treatment Groups ◽  
Total Plasma Protein ◽  
Evolutionarily Conserved ◽  
Effect Of Treatment

Abstract Galectins (GAL) constitute an evolutionarily conserved family of β-galactoside-binding proteins that are secreted. They are involved in the regulation of homeostasis, innate and adaptive immune responses to infectious challenge. The mushroom Coriolus versicolor (CV) has been reported to boost suppressed immune function, extending the survival rate and improving quality of life in man. The objective of this study was to evaluate the effect of mushroom probiotics on the secretion of Galectins in goat blood. Ten BoerXSpanish female goats (5 weeks of age) were used for this study. Powdered CV was soaked in cold water and sterile filtered. Following initial screening for infection, goats were assigned to two groups of five (n = 10). Goats were drenched daily with 10 mL cold (treatment I) extract for 4 weeks. A control group of five age-matched goats received sterile water (treatment II). Blood samples were collected on a weekly basis. The concentration plasma protein was determined by using Pierce BCA kit (Thermo Scientific Pierce, Rockford, IL). Galectins-1, -3, -8, -9 and -12 concentration was detected by using a commercial ELISA kits (ABclonal Biotechnology, Woburn, MA). There was an effect of treatment in total plasma protein concentration when compared to the control group (P &lt; 0.02). Galectins tested were secreted in both control and treatment groups. Treatment with CV decreased the concentration of Gal-1, 8 and 9 and increased the concentration of Gal-3 and -12 (P &lt; 0.05). Results from this study indicate that mushroom probiotics can modulate the secretion of GAL.

scholarly journals Tissue distribution of marbofloxacin in pigs after a single intramuscular injection

2017 ◽  
Vol 18 (2) ◽  
pp. 169 ◽  
Author(s):  
Fan Yang ◽  
Yiming Liu ◽  
Zhili Li ◽  
Yuqin Wang ◽  
Baobao Liu ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Intramuscular Injection ◽  
Single Intramuscular Injection

The relationship between muscle α -tocopherol concentration and meat oxidation in light lambs fed vitamin E supplements prior to slaughter

2014 ◽  
Vol 95 (1) ◽  
pp. 103-110 ◽  
Author(s):  
Laura González-Calvo ◽  
Guillermo Ripoll ◽  
Francisco Molino ◽  
Jorge Hugo Calvo ◽  
Margalida Joy
Keyword(s):  
Vitamin E ◽  
Tocopherol Concentration ◽  
The Relationship

scholarly journals EFEKTIVITAS MYOFASCIAL RELEASE DAN STRENGTHENING EXERCISE TERHADAP NYERI DAN PENINGKATAN AKTIVITAS FUNGSIONAL PADA KONDISI TENSION HEADACHE

2018 ◽  
Vol 2 (2) ◽  
pp. 1-9
Author(s):  
Nita Ardiani ◽  
Agus Widodo ◽  
Farid Rahman
Keyword(s):  
Sampling Method ◽  
Tension Headache ◽  
Control Group ◽  
Neck Muscle ◽  
Treatment Groups ◽  
Myofascial Release ◽  
Final Project ◽  
Muscle Work ◽  
Strengthening Exercise ◽  
Reduction Of Pain

Background:The impact of high-end student load on final project would triggerphysical stress that such as tension headache. This was influenced by ergonomicposition and neck muscle work at low level consentric. The purpose of thisresearch is knowing effect of myofascial release and strengthening exercise todecrease pain and improve functional activity for tension headache condition.Methods: This study was quasy experiment two group with control, conducted onJanuary 6 – Februari 3 2018. Sampling method by incidental sampling approach16 students were conducted for this study, divided into 2 groups. The treatmentgroup was (myofascial release and strengthening exercise) and performed painand functional measurements by using VAS (Visual Analogue Scale). dataanalysis used shapiro wilk test, leuvene test, paired sample t-test, and independentsample t-testResult: The influence of myofascial release and strengthening exercise on thedecrease of pain with the result p = 0.000, while the increase of functional activitythat is p = 0.000 which means the influence of (+) to the increase of functionalactivity. The existence of different treatment groups (myofascial release andstrenthening exercise) and the control group (strecthing) with p = 0.001.Conclusion: There was influence myofascial release and strengthening exerciseon the reduction of pain in the condition of tension headache.  

THE EFFECT OF BETAMETHASONE ON GLUCOSE PRODUCTION AND ON GLUCONEOGENESIS FROM AMINO ACIDS IN SHEEP

1974 ◽  
Vol 60 (3) ◽  
pp. 455-461 ◽  
Author(s):  
P. E. B. REILLY ◽  
E. J. H. FORD
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Plasma Glucose ◽  
Intramuscular Injection ◽  
Significant Proportion ◽  
Glucose Production ◽  
Entry Rate ◽  
Steroid Administration ◽  
Single Intramuscular Injection ◽  
Mean Glucose

SUMMARY Primed continuous infusions of tracer amounts of [U-14C]glucose and of [U-14C]labelled mixed amino acids were used to measure plasma glucose and amino acid entry rates and to obtain an index of the incorporation of amino acid carbon into glucose by sheep before and 24 h after a single intramuscular injection of betamethasone. Maximum hyperglycaemia occurred 24 h after administration of the steroid, but there was no significant change in arterial amino acid concentration. Mean glucose entry rate was significantly raised 24 h after steroid administration. The rate of incorporation of amino acid carbon into glucose also increased significantly. The increases in plasma glucose concentration and in glucose entry confirm the authors' previous results. The results also indicate that a significant proportion of the additional glucose entry is synthesized from amino acid carbon.

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