scholarly journals Fluorescence Sensing Platforms for Epinephrine Detection Based on Low Temperature Cofired Ceramics

Sensors ◽  
2020 ◽  
Vol 20 (5) ◽  
pp. 1429
Author(s):  
Sylwia Baluta ◽  
Karol Malecha ◽  
Agnieszka Świst ◽  
Joanna Cabaj
Keyword(s):  
Detection Limit ◽  
Low Temperature ◽  
High Sensitivity ◽  
Fluorescence Sensing ◽  
Free System ◽  
Injection Test ◽  
Sensing Platforms ◽  
Sensitivity And Selectivity ◽  
Cofired Ceramics ◽  
Optimized Conditions

A novel fluorescence-sensing pathway for epinephrine (EP) detection was investigated. The ceramic-based miniature biosensor was developed through the immobilization of an enzyme (laccase, tyrosinase) on a polymer—poly-(2,6-di([2,2′-bithiophen]-5-yl)-4-(5-hexylthiophen-2-yl)pyridine), based on low temperature cofired ceramics technology (LTCC). The detection procedure was based on the oxidation of the substrate, i.e., in the presence of the enzyme. An alternative enzyme-free system utilized the formation of a colorful complex between Fe2+ ions and epinephrine molecules. With the optimized conditions, the analytical performance illustrated high sensitivity and selectivity in a broad linear range with a detection limit of 0.14–2.10 nM. Moreover, the strategy was successfully used for an EP injection test with labeled pharmacological samples.

scholarly journals Copper (II) Ion-Modified Gold Nanoclusters as Peroxidase Mimetics for the Colorimetric Detection of Pyrophosphate

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5538
Author(s):  
Yunjing Shi ◽  
Jinjie Wang ◽  
Kun Mu ◽  
Suqin Liu ◽  
Guang Yang ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Detection Limit ◽  
Chemical Stability ◽  
Human Urine ◽  
Detection Method ◽  
Colorimetric Detection ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Sensitivity And Selectivity ◽  
Optimized Conditions

Copper (II) ions have been shown to greatly improve the chemical stability and peroxidase-like activity of gold nanoclusters (AuNCs). Since the affinity between Cu2+ and pyrophosphate (PPi) is higher than that between Cu2+ and AuNCs, the catalytic activity of AuNCs-Cu2+ decreases with the introduction of PPi. Based on this principle, a new colorimetric detection method of PPi with high sensitivity and selectivity was developed by using AuNCs-Cu2+ as a probe. Under optimized conditions, the detection limit of PPi was 0.49 nM with a linear range of 0.51 to 30,000 nM. The sensitivity of the method was three orders of magnitude higher than that of a fluorescence method using AuNCs-Cu2+ as the probe. Finally, the AuNCs-Cu2+ system was successfully applied to directly determine the concentration of PPi in human urine samples.

Surface molecular imprinting on CdTe quantum dots for fluorescence sensing of 4-nitrophenol

2016 ◽  
Vol 8 (10) ◽  
pp. 2226-2232 ◽  
Author(s):  
Linye Jiang ◽  
Haijian Liu ◽  
Ming Li ◽  
Yue Xing ◽  
Xueqin Ren
Keyword(s):  
Quantum Dots ◽  
Detection Limit ◽  
Molecular Imprinting ◽  
Fluorescent Sensor ◽  
High Sensitivity ◽  
Surface Molecular Imprinting ◽  
Fluorescence Sensing ◽  
Lower Detection Limit ◽  
Lower Detection ◽  
Sensitivity And Selectivity

The developed fluorescent sensor provides high sensitivity and selectivity and a lower detection limit than previously developed sensors.

A metal-organic framework featuring highly sensitive fluorescence sensing for Al3+ ion

CrystEngComm ◽  
2021 ◽  
Author(s):  
Yang Qiao ◽  
Zeqi Li ◽  
Mei-Hui Yu ◽  
Ze Chang ◽  
Xian-He Bu
Keyword(s):  
Metal Ions ◽  
Human Health ◽  
Metal Organic Framework ◽  
High Sensitivity ◽  
Fluorescence Sensing ◽  
Sensing Material ◽  
Highly Sensitive ◽  
Sensitivity And Selectivity ◽  
Metal Organic ◽  
Organic Framework

High sensitivity and selectivity for detection of metal ions are very important to protect human health. Fluorescent metal-organic framework (MOF) as a new sensing material has attracted more and more...

scholarly journals A highly selective and sensitive H2S sensor at low temperatures based on Cr-doped α-Fe2O3 nanoparticles

RSC Advances ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 4150-4156 ◽  
Author(s):  
Dongyang Xue ◽  
Rui Zhou ◽  
Xiaoping Lin ◽  
Xiaochuan Duan ◽  
Qiuhong Li ◽  
...  
Keyword(s):  
Low Temperature ◽  
Low Temperatures ◽  
Hydrothermal Reaction ◽  
High Sensitivity ◽  
Fe2o3 Nanoparticles ◽  
Sensitivity And Selectivity ◽  
One Step

Cr-doped α-Fe2O3 nanoparticles were synthesized by one-step hydrothermal reaction and showed high sensitivity and selectivity to H2S at low temperature.

scholarly journals Label-Free Split Aptamer Sensor for Femtomolar Detection of Dopamine by Means of Flexible Organic Electrochemical Transistors

Materials ◽  
2020 ◽  
Vol 13 (11) ◽  
pp. 2577 ◽  
Author(s):  
Yuanying Liang ◽  
Ting Guo ◽  
Lei Zhou ◽  
Andreas Offenhäusser ◽  
Dirk Mayer
Keyword(s):  
Detection Limit ◽  
Electrochemical Sensors ◽  
Limit Of Detection ◽  
High Sensitivity ◽  
Label Free ◽  
Dopamine Detection ◽  
Electrochemical Transistor ◽  
Sensitivity And Selectivity

The detection of chemical messenger molecules, such as neurotransmitters in nervous systems, demands high sensitivity to measure small variations, selectivity to eliminate interferences from analogues, and compliant devices to be minimally invasive to soft tissue. Here, an organic electrochemical transistor (OECT) embedded in a flexible polyimide substrate is utilized as transducer to realize a highly sensitive dopamine aptasensor. A split aptamer is tethered to a gold gate electrode and the analyte binding can be detected optionally either via an amperometric or a potentiometric transducer principle. The amperometric sensor can detect dopamine with a limit of detection of 1 μM, while the novel flexible OECT-based biosensor exhibits an ultralow detection limit down to the concentration of 0.5 fM, which is lower than all previously reported electrochemical sensors for dopamine detection. The low detection limit can be attributed to the intrinsic amplification properties of OECTs. Furthermore, a significant response to dopamine inputs among interfering analogues hallmarks the selective detection capabilities of this sensor. The high sensitivity and selectivity, as well as the flexible properties of the OECT-based aptasensor, are promising features for their integration in neuronal probes for the in vitro or in vivo detection of neurochemical signals.

scholarly journals A highly selective and sensitive fluorescent probe for lactate dehydrogenase based on ultrabright adenosine monophosphate capped gold nanoclusters

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13438-13443 ◽  
Author(s):  
Jiao Liu ◽  
Hong-Wei Li ◽  
Yuqing Wu
Keyword(s):  
Lactate Dehydrogenase ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Fluorescence Probe ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Adenosine Monophosphate ◽  
Low Detection Limit ◽  
Sensitivity And Selectivity

The ultrabright AuNCs@AMP are used as fluorescence probe to detect lactate dehydrogenase (LDH) with high sensitivity and selectivity, showing an extremely low detection limit of 0.2 nM (26 pg μL−1, 0.8 U L−1).

Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66774-66778 ◽  
Author(s):  
Prithidipa Sahoo ◽  
Himadri Sekhar Sarkar ◽  
Sujoy Das ◽  
Kalipada Maiti ◽  
Md Raihan Uddin ◽  
...  
Keyword(s):  
Uric Acid ◽  
Fluorescent Probe ◽  
High Sensitivity ◽  
Living Cells ◽  
Live Cells ◽  
Fluorescence Sensing ◽  
Turn On ◽  
Sensitivity And Selectivity ◽  
First Time

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved.

Fabrication of SnO2–SnO nanocomposites with p–n heterojunctions for the low-temperature sensing of NO2 gas

Nanoscale ◽  
2015 ◽  
Vol 7 (28) ◽  
pp. 12133-12142 ◽  
Author(s):  
Lei Li ◽  
Chunmei Zhang ◽  
Wei Chen
Keyword(s):  
Low Temperature ◽  
High Sensitivity ◽  
Temperature Sensing ◽  
Gas Detection ◽  
Hybrid Nanostructure ◽  
Sensitivity And Selectivity ◽  
Sensing Performance

A SnO2–SnO hybrid nanostructure with p–n heterojunctions exhibits enhanced sensing performance for NO2 gas detection with high sensitivity and selectivity.

scholarly journals Water Pollution Control and Treatment Based on Quantum Dot Chemical and Biological High-Sensitivity Sensing

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Guihua Zheng ◽  
Shiyao Li ◽  
Ting Zhang ◽  
Feiyun Zhu ◽  
Jing Sun ◽  
...  
Keyword(s):  
Water Pollution ◽  
Detection Limit ◽  
Quantum Yield ◽  
Pollution Prevention ◽  
High Sensitivity ◽  
Ammonium Citrate ◽  
Selective Detection ◽  
Ferric Ion ◽  
Inorganic Pollutants ◽  
Fluorescence Sensing

Inorganic pollutants in water can have an important impact on ecosystems and human health, so the development of rapid and sensitive detection methods for typical inorganic pollutants in water samples is important for understanding the pollution status of the water environment, as well as water pollution prevention and protection of drinking water safety. Fluorescence sensing technology has the advantages of fast response, high sensitivity, simple operation, and low cost but still has the problems of low quantum yield, cumbersome construction process, and limited practical applications. Based on the excellent fluorescence properties, a series of fluorescence sensing was constructed for the rapid, highly sensitive, and selective detection of various typical inorganic pollutants in water. And the related fluorescence sensing mechanism was investigated in this paper. In this paper, nitrogen/sulfur codoped carbon quantum dots (N, S-CQDs) were prepared for the sensitive and selective detection of sulfide and ferric ion. The blue fluorescent N, S-CQDs were prepared by a one-step hydrothermal method using ammonium citrate and L-cysteine as raw materials, which have excitation wavelength dependence and fluorescence quantum yield of 16.1% for the selective detection of sulfides with a detection limit ( S / N = 3 ) of 11.0 nM (about 0.35 μg/L). CQDs with significantly higher fluorescence quantum yields (69%) and no excitation dependence were prepared when citric acid was used instead of ammonium citrate and were used for the selective detection of ferric ion with a detection limit of 14.0 nM (~0.8 μg/L). The method has been successfully applied to the determination of total phosphorus in surface water and human urine, and the fluorescence color change of the dual-emission sensing can be used for the naked-eye identification and semiquantitative detection of phosphate.

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