Pyrene appended thymine derivative for selective turn-on fluorescence sensing of uric acid in live cells

RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66774-66778 ◽  
Author(s):  
Prithidipa Sahoo ◽  
Himadri Sekhar Sarkar ◽  
Sujoy Das ◽  
Kalipada Maiti ◽  
Md Raihan Uddin ◽  
...  

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved.

RSC Advances ◽  
2015 ◽  
Vol 5 (59) ◽  
pp. 47990-47996 ◽  
Author(s):  
Shaodan Wang ◽  
Hai Xu ◽  
Qingbiao Yang ◽  
Yan Song ◽  
Yaoxian Li

A triphenylamine–hemicyanine dye was developed as a colorimetric and turn-on fluorescent probe for detection of cyanide with high sensitivity and selectivity.


2019 ◽  
Vol 48 (38) ◽  
pp. 14408-14417 ◽  
Author(s):  
Xubin Zheng ◽  
Ruiqing Fan ◽  
Haoyang Lu ◽  
Bowen Wang ◽  
Jingkun Wu ◽  
...  

A fluorescent probe designed and prepared through postsynthetic modification (PSM) showed high sensitivity and selectivity for N-methylformamide (NMF) in urine and methylglyoxal (MGO) in serum.


Biosensors ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 130
Author(s):  
Ruo-Jun Man ◽  
Meng-Ke Wu ◽  
Bing Yang ◽  
Yu-Shun Yang

In this work, a novel fluorescent probe with first-time-selected thiazepine backbone, TZPzine-1, was developed for selective detection of hydrazine in water samples and living cells. Chosen from our recent anti-cancer agents, TZPzine-1 inferred structurally based advantages of the optical adjustability and the hydrazine-trapping approach. It also showed applicable properties including high sensitivity (LOD = 50 nM), wide linear range (0–15 equiv.), high selectivity (especially from competing species), rapid response (within 20 min), and practical steadiness in various pH (6.0–11.0) and temperature (15–50 °C) conditions. To satisfy the interdisciplinary requirements in environmental toxicology, TZPzine-1 was successfully applied in water samples and living cells. We hope that the information in this work, as well as the concept of monitoring the nitrogen cycle, may be referable for future research on systematic management.


2017 ◽  
Vol 9 (37) ◽  
pp. 5472-5477 ◽  
Author(s):  
Feng Wu ◽  
Yue Zhang ◽  
Lei Huang ◽  
Dan Xu ◽  
Hongying Wang

An anthracene carboxyimide-based fluorescent probe was developed for rapid detection of formaldehyde in living cells with high sensitivity and selectivity.


2021 ◽  
Author(s):  
Abdul Hadi Mehmood ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Wenhui Song ◽  
Yaru Sun ◽  
...  

An effective turn-on ER-targeting fluorescent probe ER-DTT was designed to image DTT of endoplasmic reticulum for the first time.


2019 ◽  
Vol 55 (24) ◽  
pp. 3473-3476 ◽  
Author(s):  
Xin Wang ◽  
Nan Ma ◽  
Rui Wu ◽  
Ke Ding ◽  
Zhengqiu Li

A series of reaction-based probes have been developed by conjugation of maleimide–coumarin into ibrutinib. The resulting probes display high sensitivity and selectivity toward BTK, and were proven to be suitable for simultaneous protein labeling and no-wash imaging of BTK inside live mammalian cells.


2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.


Author(s):  
Ju-Peng Chen ◽  
Yi-Meng Duan ◽  
Wen-Jun Zheng ◽  
Qi Zhang ◽  
Qianshou Zong ◽  
...  

2015 ◽  
Vol 51 (32) ◽  
pp. 6925-6927 ◽  
Author(s):  
Fanpeng Kong ◽  
Xiaoyue Meng ◽  
Ranran Chu ◽  
Kehua Xu ◽  
Bo Tang

Based on a unique elimination reaction prompted by the iodide, a turn-on fluorescent probe (HCy-OMe-Br) without containing heavy metal has been developed for the first time. The probe can monitor iodide with excellent selectivity and sensitivity and was successfully applied to visualize iodide in living cells.


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