scholarly journals A highly selective and sensitive fluorescent probe for lactate dehydrogenase based on ultrabright adenosine monophosphate capped gold nanoclusters

RSC Advances ◽  
2017 ◽  
Vol 7 (22) ◽  
pp. 13438-13443 ◽  
Author(s):  
Jiao Liu ◽  
Hong-Wei Li ◽  
Yuqing Wu
Keyword(s):  
Lactate Dehydrogenase ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Fluorescence Probe ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Adenosine Monophosphate ◽  
Low Detection Limit ◽  
Sensitivity And Selectivity

The ultrabright AuNCs@AMP are used as fluorescence probe to detect lactate dehydrogenase (LDH) with high sensitivity and selectivity, showing an extremely low detection limit of 0.2 nM (26 pg μL−1, 0.8 U L−1).

A novel FRET-based fluorescent probe for the selective detection of hydrogen sulfide (H2S) and its application for bioimaging

2018 ◽  
Vol 6 (30) ◽  
pp. 4903-4908 ◽  
Author(s):  
Qi Zhao ◽  
Fangjun Huo ◽  
Jin Kang ◽  
Yongbin Zhang ◽  
Caixia Yin
Keyword(s):  
Hydrogen Sulfide ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Nude Mice ◽  
High Sensitivity ◽  
Fast Response ◽  
Living Cells ◽  
Selective Detection ◽  
Low Detection Limit ◽  
Sensitivity And Selectivity

Herein, our group developed a fast response fluorescent probe (Flu-N3) for H2S on the basis of the 7-amino-4-methylcoumarin and fluorescein FRET system with high sensitivity and selectivity and a low detection limit of 0.031 μM. Moreover, the probe was successfully applied to image exogenous and endogenous H2S in living cells and nude mice.

scholarly journals Copper (II) Ion-Modified Gold Nanoclusters as Peroxidase Mimetics for the Colorimetric Detection of Pyrophosphate

Sensors ◽  
2021 ◽  
Vol 21 (16) ◽  
pp. 5538
Author(s):  
Yunjing Shi ◽  
Jinjie Wang ◽  
Kun Mu ◽  
Suqin Liu ◽  
Guang Yang ◽  
...  
Keyword(s):  
Catalytic Activity ◽  
Detection Limit ◽  
Chemical Stability ◽  
Human Urine ◽  
Detection Method ◽  
Colorimetric Detection ◽  
Gold Nanoclusters ◽  
High Sensitivity ◽  
Sensitivity And Selectivity ◽  
Optimized Conditions

Copper (II) ions have been shown to greatly improve the chemical stability and peroxidase-like activity of gold nanoclusters (AuNCs). Since the affinity between Cu2+ and pyrophosphate (PPi) is higher than that between Cu2+ and AuNCs, the catalytic activity of AuNCs-Cu2+ decreases with the introduction of PPi. Based on this principle, a new colorimetric detection method of PPi with high sensitivity and selectivity was developed by using AuNCs-Cu2+ as a probe. Under optimized conditions, the detection limit of PPi was 0.49 nM with a linear range of 0.51 to 30,000 nM. The sensitivity of the method was three orders of magnitude higher than that of a fluorescence method using AuNCs-Cu2+ as the probe. Finally, the AuNCs-Cu2+ system was successfully applied to directly determine the concentration of PPi in human urine samples.

Design of Photoionization Detector Based on the Miniature Gas Chromatography

2013 ◽  
Vol 823 ◽  
pp. 291-295 ◽  
Author(s):  
Shou Chen Chai ◽  
Peng Yang ◽  
Cheng Jia Yang ◽  
Chun Li Cai ◽  
Na Yu
Keyword(s):  
Gas Chromatography ◽  
Detection Limit ◽  
Ionization Chamber ◽  
High Sensitivity ◽  
Fast Response ◽  
Low Detection Limit ◽  
Photoionization Detector ◽  
Key Factor ◽  
The Stability ◽  
Sensitivity Detection

In the space restricted airtight environment that people lives in, detecting harmful gas by miniature gas chromatography is the practical requirement at present, however, PIDs performance is key factor that restrict the application of miniature gas chromatography, the redesign of the detectors gas route in this paper aiming at improve detectors stability observably, and schemed out miniature PID with high sensitivity, low detection limit and fast response. The result of the experiment shows that the detection limit is 0.04ppm, the sensitivity is 101mv/ppm,the stability is 0.04×10-6/24h,meeting the project requirement. Keywords: photoionization detector; ionization chamber; sensitivity; detection limit;

Dissolution-enhanced emission of 1,3,6,8-Tetrakis(p-benzoic acid)pyrene for selectively detecting protamine and “on-to-on” heparin detection in water

2021 ◽  
Author(s):  
Hongtao Li ◽  
Yuting Zhang ◽  
Yan Huang ◽  
Dapeng Cao ◽  
Shitao Wang
Keyword(s):  
Detection Limit ◽  
Benzoic Acid ◽  
Organic Molecule ◽  
Basic Protein ◽  
Fluorescence Probe ◽  
Small Organic Molecule ◽  
Turn On ◽  
Low Detection Limit

We developed a small organic molecule, the 1,3,6,8-Tetrakis(pbenzoic acid)pyrene (TBAPy) as a facile turn-on fluorescence probe for selectively detecting the basic protein protamine in water with a low detection limit...

A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening

2014 ◽  
Vol 50 (63) ◽  
pp. 8677 ◽  
Author(s):  
Yongqian Xu ◽  
Benhao Li ◽  
Liangliang Xiao ◽  
Jia Ouyang ◽  
Shiguo Sun ◽  
...  
Keyword(s):  
Acid Phosphatase ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
High Sensitivity ◽  
Inhibitor Screening ◽  
Sensitivity And Selectivity

The synthesis and bioimaging of a biocompatible hydrogen sulfide fluorescent probe with high sensitivity and selectivity

The Analyst ◽  
2020 ◽  
Vol 145 (6) ◽  
pp. 2305-2310 ◽  
Author(s):  
Ruqiao Zhou ◽  
Guiling Cui ◽  
Qingrong Qi ◽  
Wencai Huang ◽  
Li Yang
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
High Sensitivity ◽  
The Past ◽  
Sensitivity And Selectivity ◽  
Poisonous Gas

Hydrogen sulfide (H2S), a well-known poisonous gas, has been recognized as a critical endogenous gas transmitter in the past decade.

scholarly journals Marine Toxins Detection by Biosensors Based on Aptamers

Toxins ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 1 ◽  
Author(s):  
Wei Ye ◽  
Taomei Liu ◽  
Weimin Zhang ◽  
Muzi Zhu ◽  
Zhaoming Liu ◽  
...  
Keyword(s):  
Detection Limit ◽  
Sensitivity And Specificity ◽  
High Efficiency ◽  
Rapid Development ◽  
High Sensitivity ◽  
Detection Methods ◽  
Marine Toxins ◽  
Time Saving ◽  
Low Detection Limit ◽  
The Future

Marine toxins cause great harm to human health through seafood, therefore, it is urgent to exploit new marine toxins detection methods with the merits of high sensitivity and specificity, low detection limit, convenience, and high efficiency. Aptasensors have emerged to replace classical detection methods for marine toxins detection. The rapid development of molecular biological approaches, sequencing technology, material science, electronics and chemical science boost the preparation and application of aptasensors. Taken together, the aptamer-based biosensors would be the best candidate for detection of the marine toxins with the merits of high sensitivity and specificity, convenience, time-saving, relatively low cost, extremely low detection limit, and high throughput, which have reduced the detection limit of marine toxins from nM to fM. This article reviews the detection of marine toxins by aptamer-based biosensors, as well as the selection approach for the systematic evolution of ligands by exponential enrichment (SELEX), the aptamer sequences. Moreover, the newest aptasensors and the future prospective are also discussed, which would provide thereotical basis for the future development of marine toxins detection by aptasensors.

scholarly journals A sensitive and selective fluorescent probe for hydrazine with a unique nonaromatic fluorophore

RSC Advances ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 5572-5578
Author(s):  
Jian Liu ◽  
Tao Li ◽  
Shun Wang ◽  
Qingrong Qi ◽  
Hang Song ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
Stokes Shift ◽  
Large Stokes Shift ◽  
Low Detection Limit

A novel fluorescent probe for hydrazine with low detection limit and large Stokes shift was developed.

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