Unusual Features of the Oncogenicity of Chicken Embryo Lethal Orphan (CELO) Virus in Hamsters1

2015 ◽  
pp. 56-88 ◽  
Author(s):  
Bonnie B. Asch ◽  
Kenneth J. McCormick ◽  
John J. Trentin
Keyword(s):  
Chicken Embryo ◽  
Celo Virus

Chicken Embryo Lethal Orphan (CELO) Virus DNA Present in Hamster Cell Lines Derived from CELO-Induced Hepatomas

Intervirology ◽  
1978 ◽  
Vol 9 (5) ◽  
pp. 321-324 ◽  
Author(s):  
John T. May ◽  
James K. Welsh ◽  
Bonnie B. Asch ◽  
Kenneth J. McCormick
Keyword(s):  
Cell Lines ◽  
Chicken Embryo ◽  
Celo Virus

The Chicken-Embryo-Lethal-Orphan (CELO) Virus as a Tissue-Culture Contaminant

1962 ◽  
Vol 6 (4) ◽  
pp. 406 ◽  
Author(s):  
Vance J. Yates ◽  
Dharam V. Ablashi ◽  
Pei W. Chang ◽  
Dorothy E. Fry
Keyword(s):  
Tissue Culture ◽  
Chicken Embryo ◽  
Celo Virus

Purification, Physical Features, and Electron Microscopy of Celo Virus

1970 ◽  
Vol 28 ◽  
pp. 166-167
Author(s):  
W. A. Stenback ◽  
J. P. Anderson ◽  
K. J. McCormick ◽  
J. J. Trentin
Keyword(s):  
Electron Microscopy ◽  
Chicken Embryo ◽  
Allantoic Fluid ◽  
Human Cells ◽  
Potential Candidate ◽  
Cancer Etiology ◽  
Avian Adenovirus ◽  
Celo Virus ◽  
Physical Features

Chicken-embryo-lethal-orphan (CELO) virus is an avian adenovirus shown to be oncogenic in newborn random bred and inbred hamsters (1). Transformation of human cells by this agent has been reported (2). This virus is ubiquitously present in chickens and market eggs and is therefore considered to be a potential candidate for cancer etiology in man.Virus for the present study was inoculated into 10-day CELO-free embryonated eggs, and crude stocks consisted of 72-hr allantoic fluid harvests. To 80 ml of crude stock was added 0. 8 gm Na-deoxycholate and 4. 0 ml of 0. 25% trypsin, and the mixture incubated at 37 C for 30 min.

Cytoplasmic Tubules in Cells Infected with Laryngotracheitis Virus

1969 ◽  
Vol 27 ◽  
pp. 376-377
Author(s):  
A. M. Watrach
Keyword(s):  
Tissue Culture ◽  
Small Proportion ◽  
Chicken Embryo ◽  
Culture Cells ◽  
Tissue Culture Cells ◽  
Morphologic Characteristics ◽  
Infectious Laryngotracheitis ◽  
Laryngotracheitis Virus ◽  
In Cells

During a study of the development of infectious laryngotracheitis (LT) virus in tissue culture cells, unusual tubular formations were found in the cytoplasm of a small proportion of the affected cells. It is the purpose of this report to describe the morphologic characteristics of the tubules and to discuss their possible association with the development of virus.The source and maintenance of the strain of LT virus have been described. Prior to this study, the virus was passed several times in chicken embryo kidney (CEK) tissue culture cells.

scholarly journals Calcium Carbonate Nanoparticles—Toxicity and Effect of In Ovo Inoculation on Chicken Embryo Development, Broiler Performance and Bone Status

Animals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 932
Author(s):  
Arkadiusz Matuszewski ◽  
Monika Łukasiewicz ◽  
Jan Niemiec ◽  
Maciej Kamaszewski ◽  
Sławomir Jaworski ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Embryo Development ◽  
Bone Quality ◽  
Chicken Embryo ◽  
Broiler Chickens ◽  
Selection Procedure ◽  
High Specificity ◽  
Control Group ◽  
In Ovo

The use of intensive selection procedure in modern broiler chicken lines has led to the development of several skeletal disorders in broiler chickens. Therefore, current research is focused on methods to improve the bone quality in birds. In ovo technology, using nanoparticles with a high specificity to bones, is a potential approach. The present study aimed to evaluate the effect of in ovo inoculation (IOI) of calcium carbonate nanoparticles (CCN) on chicken embryo development, health status, bone characteristics, and on broiler production results and bone quality. After assessing in vitro cell viability, the IOI procedure was performed with an injection of 500 μg/mL CCN. The control group was not inoculated with CCN. Hatchability, weight, and selected bone and serum parameters were measured in embryos. Part of hatchlings were reared under standard conditions until 42 days, and production results, meat quality, and bone quality of broilers were determined. CCN did not show cytotoxicity to cells and chicken embryo and positively influenced bone parameters of the embryos and of broilers later (calcification) without negatively affecting the production results. Thus, the IOI of CCN could modify the molecular responses at the stage of embryogenesis, resulting in better mineralization, and could provide a sustained effect, thereby improving bone quality in adult birds.

Sign in / Sign up

Export Citation Format

Share Document