scholarly journals miR‐34c works downstream of p53 leading to dairy goat male germline stem‐cell ( mGSC s) apoptosis

2013 ◽  
Vol 46 (2) ◽  
pp. 223-231 ◽  
Author(s):  
M. Li ◽  
M. Yu ◽  
C. Liu ◽  
H. Zhu ◽  
X. He ◽  
...  
Keyword(s):  
Stem Cell ◽  
Dairy Goat ◽  
Germline Stem Cell ◽  
Male Germline

PLZF-Induced Upregulation of CXCR4 Promotes Dairy Goat Male Germline Stem Cell Proliferation by Targeting Mir146a

2015 ◽  
Vol 117 (4) ◽  
pp. 844-852 ◽  
Author(s):  
Hailong Mu ◽  
Na Li ◽  
Jiang Wu ◽  
Liming Zheng ◽  
Yuanxin Zhai ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Stem Cell ◽  
Dairy Goat ◽  
Germline Stem Cell ◽  
Stem Cell Proliferation ◽  
Male Germline

miR-544 Regulates Dairy Goat Male Germline Stem Cell Self-Renewal via Targeting PLZF

2015 ◽  
Vol 116 (10) ◽  
pp. 2155-2165 ◽  
Author(s):  
Wencong Song ◽  
Hailong Mu ◽  
Jiang Wu ◽  
Mingzhi Liao ◽  
Haijing Zhu ◽  
...  
Keyword(s):  
Stem Cell ◽  
Dairy Goat ◽  
Germline Stem Cell ◽  
Self Renewal ◽  
Male Germline

scholarly journals Klp10A, a stem cell centrosome-enriched kinesin, balances asymmetries in Drosophila male germline stem cell division

eLife ◽  
2016 ◽  
Vol 5 ◽  
Author(s):  
Cuie Chen ◽  
Mayu Inaba ◽  
Zsolt G Venkei ◽  
Yukiko M Yamashita
Keyword(s):  
Stem Cell ◽  
Cell Division ◽  
Cell Fate ◽  
Germline Stem Cell ◽  
Germline Stem Cells ◽  
Male Germline ◽  
Mother And Daughter ◽  
Stem Cell Divisions ◽  
Stem Cell Division ◽  
Male Germline Stem Cells

Asymmetric stem cell division is often accompanied by stereotypical inheritance of the mother and daughter centrosomes. However, it remains unknown whether and how stem cell centrosomes are uniquely regulated and how this regulation may contribute to stem cell fate. Here we identify Klp10A, a microtubule-depolymerizing kinesin of the kinesin-13 family, as the first protein enriched in the stem cell centrosome in Drosophila male germline stem cells (GSCs). Depletion of klp10A results in abnormal elongation of the mother centrosomes in GSCs, suggesting the existence of a stem cell-specific centrosome regulation program. Concomitant with mother centrosome elongation, GSCs form asymmetric spindle, wherein the elongated mother centrosome organizes considerably larger half spindle than the other. This leads to asymmetric cell size, yielding a smaller differentiating daughter cell. We propose that klp10A functions to counteract undesirable asymmetries that may result as a by-product of achieving asymmetries essential for successful stem cell divisions.

scholarly journals Asymmetric Division of Drosophila Male Germline Stem Cell Shows Asymmetric Histone Distribution

Science ◽  
2012 ◽  
Vol 338 (6107) ◽  
pp. 679-682 ◽  
Author(s):  
V. Tran ◽  
C. Lim ◽  
J. Xie ◽  
X. Chen
Keyword(s):  
Stem Cell ◽  
Asymmetric Division ◽  
Germline Stem Cell ◽  
Male Germline

scholarly journals Recent advances in Drosophila male germline stem cell biology

2012 ◽  
Vol 2 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Erika L. Matunis ◽  
Rachel R. Stine ◽  
Margaret de Cuevas
Keyword(s):  
Stem Cell ◽  
Cell Biology ◽  
Germline Stem Cell ◽  
Stem Cell Biology ◽  
Male Germline ◽  
Recent Advances
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