scholarly journals Recent advances in Drosophila male germline stem cell biology

2012 ◽  
Vol 2 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Erika L. Matunis ◽  
Rachel R. Stine ◽  
Margaret de Cuevas
2004 ◽  
Vol 11 (6) ◽  
pp. 392-398 ◽  
Author(s):  
Jesper Bonde ◽  
David A Hess ◽  
Jan A Nolta

2019 ◽  
Vol 46 (3) ◽  
pp. E10 ◽  
Author(s):  
Michael C. Jin ◽  
Zachary A. Medress ◽  
Tej D. Azad ◽  
Vanessa M. Doulames ◽  
Anand Veeravagu

Recent advances in stem cell biology present significant opportunities to advance clinical applications of stem cell–based therapies for spinal cord injury (SCI). In this review, the authors critically analyze the basic science and translational evidence that supports the use of various stem cell sources, including induced pluripotent stem cells, oligodendrocyte precursor cells, and mesenchymal stem cells. They subsequently explore recent advances in stem cell biology and discuss ongoing clinical translation efforts, including combinatorial strategies utilizing scaffolds, biogels, and growth factors to augment stem cell survival, function, and engraftment. Finally, the authors discuss the evolution of stem cell therapies for SCI by providing an overview of completed (n = 18) and ongoing (n = 9) clinical trials.


2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Michail-Dimitrios Papaioannou ◽  
Kevin Sangster ◽  
Rifat Shahriar Sajid ◽  
Ugljesa Djuric ◽  
Phedias Diamandis

AbstractGlioblastoma is an aggressive form of brain cancer that has seen only marginal improvements in its bleak survival outlook of 12–15 months over the last forty years. There is therefore an urgent need for the development of advanced drug screening platforms and systems that can better recapitulate glioblastoma’s infiltrative biology, a process largely responsible for its relentless propensity for recurrence and progression. Recent advances in stem cell biology have allowed the generation of artificial tridimensional brain-like tissue termed cerebral organoids. In addition to their potential to model brain development, these reagents are providing much needed synthetic humanoid scaffolds to model glioblastoma’s infiltrative capacity in a faithful and scalable manner. Here, we highlight and review the early breakthroughs in this growing field and discuss its potential future role for glioblastoma research.


2014 ◽  
Vol 9 (7) ◽  
pp. 684 ◽  
Author(s):  
Jinhui Chen ◽  
Libing Zhou ◽  
Su-yue Pan

2009 ◽  
Vol 53 (8-9-10) ◽  
pp. 1329-1339 ◽  
Author(s):  
John Pearson ◽  
Lourdes Lopez-Onieva ◽  
Patricia Rojas-Rios ◽  
Acaimo Gonzalez-Reyes

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