DNA repair characteristics and mutability of the UV-sensitive V79 Chinese hamster cell mutant V-B11 (complementation group 7)

Mutagenesis ◽  
1991 ◽  
Vol 6 (3) ◽  
pp. 179-183 ◽  
Author(s):  
M.Z. Zdzienicka ◽  
D.L. Mitchell ◽  
J. Venema ◽  
A. van Hoffen ◽  
A.A. van Zeeland ◽  
...  
Keyword(s):  
Dna Repair ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Complementation Group ◽  
Cell Mutant

The Chinese hamster cell mutant V-H4 is homologous to Fanconi anemia (complementation group A)

1991 ◽  
Vol 56 (1) ◽  
pp. 23-26 ◽  
Author(s):  
F. Arwert ◽  
M.A. Rooimans ◽  
A. Westerveld ◽  
J.W.I.M. Simons ◽  
M.Z. Zdzienicka
Keyword(s):  
Fanconi Anemia ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Complementation Group ◽  
Cell Mutant ◽  
Group A

Chinese hamster cell mutant, V-C8, a model for analysis of Brca2 function

2006 ◽  
Vol 600 (1-2) ◽  
pp. 79-88 ◽  
Author(s):  
Wouter W. Wiegant ◽  
René M. Overmeer ◽  
Barbara C. Godthelp ◽  
Paul P.W. van Buul ◽  
Małgorzata Z. Zdzienicka
Keyword(s):  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Cell Mutant

Genetic diversity of mitomycin C-hypersensitive Chinese hamster cell mutants: A new complementation group with chromosomal instability

1993 ◽  
Vol 19 (5) ◽  
pp. 431-437 ◽  
Author(s):  
W. J. I. Overkamp ◽  
M. A. Rooimans ◽  
I. Neuteboom ◽  
P. Telleman ◽  
F. Arwert ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Mitomycin C ◽  
Chromosomal Instability ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Complementation Group

A novel type of X-ray-sensitive Chinese hamster cell mutant with radioresistant DNA synthesis and hampered DNA double-strand break repair

1995 ◽  
Vol 337 (2) ◽  
pp. 119-129 ◽  
Author(s):  
Gerald W.C.T Verhaegh ◽  
Wim Jongmans ◽  
Bruno Morolli ◽  
Nicolaas G.J Jaspers ◽  
Govert P van der Schans ◽  
...  
Keyword(s):  
Dna Synthesis ◽  
Chinese Hamster ◽  
Strand Break ◽  
Chinese Hamster Cell ◽  
Double Strand Break ◽  
Double Strand Break Repair ◽  
Cell Mutant ◽  
X Ray ◽  
Dna Double Strand Break ◽  
Break Repair

scholarly journals Identification and characterization of a third complementation group of emetine-resistant Chinese hamster cell mutants.

1981 ◽  
Vol 1 (1) ◽  
pp. 58-65 ◽  
Author(s):  
J J Wasmuth ◽  
J M Hill ◽  
L S Vock
Keyword(s):  
Chinese Hamster Ovary ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Resistant Cell ◽  
Complementation Group ◽  
Ovary Cells ◽  
Complementation Groups ◽  
Resistant Mutants ◽  
Biosynthetic Machinery

We have isolated emetine-resistant cell lines from Chinese hamster peritoneal fibroblasts and have shown that they represent a third distinct class or complementation group of emetine-resistant mutants, as determined by three different criteria. These mutants, like those belonging to the two other complementation groups we have previously defined, which were isolated from Chinese hamster lung and Chinese hamster ovary cells, have alterations that directly affect the protein biosynthetic machinery. So far, there is absolute cell line specificity with respect to the three complementation groups, in that all the emetine-resistant mutants we have isolated from Chinese hamster lung cells belong to one complementation group, all those we have isolated from Chinese hamster ovary cells belong to a second complementation group, and all those isolated from Chinese hamster peritoneal cells belong to a third complementation group. Thus, in cultured Chinese hamster cells, mutations in at least three different loci, designated emtA, emtB, and emtC, encoding for different components of the protein biosynthetic machinery, can give rise to the emetine-resistant phenotype.

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