scholarly journals Enteroaggregative Escherichia coli as a Cause of Traveler's Diarrhea: Clinical Response to Ciprofloxacin

1999 ◽  
Vol 29 (2) ◽  
pp. 335-338 ◽  
Author(s):  
Mariela Glandt ◽  
Javier A. Adachi ◽  
John J. Mathewson ◽  
Zhi‐Dong Jiang ◽  
Daniel DiCesare ◽  
...  
2019 ◽  
Vol 8 (27) ◽  
Author(s):  
Denish Piya ◽  
Lauren Lessor ◽  
Mei Liu ◽  
Jason J. Gill

ABSTRACT Here, we describe the complete genome sequence of siphophage LL5. LL5 is a T1-like phage isolated against enterotoxigenic Escherichia coli, which causes traveler’s diarrhea. LL5 is included as a component phage in the commercial prebiotic product PreforPro.


1976 ◽  
Vol 3 (5) ◽  
pp. 486-495
Author(s):  
G K Morris ◽  
M H Merson ◽  
D A Sack ◽  
J G Wells ◽  
W T Martin ◽  
...  

A laboratory investigation was conducted on cultures collected from travelers before, during, and after a trip to Mexico to characterize the etiology of traveler's diarrhea. Four laboratory methods for detecting enterotoxigenicity of Escherichia coli were evaluated: the infant mouse assay, the Chinese hamster ovary (CHO) cell assay, the Y1 adrenal cell assay, and the rabbit ileal loop. Although a number of common enteric pathogens were identified as a cause of traveler's diarrhea, including six serotypes of Salmonella, two serotypes of Shigella, Vibrio parahaemolyticus, Giardia lamblia, and Entamoeba histolytica, enterotoxigenic Escherichia coli was most commonly isolated. Strains were identified that produced only heat-labile enterotoxin (LT), only heat-stable enterotoxin (ST), or both LT and ST. The infant mouse assay yielded results falling into two distinct groups, providing a clear separation of positive and negative cultures. The CHO assay also formed two groups, with positive cultures producing 11% or more of the elongated cells. There was good agreement between the CHO and the Y1 adrenal cell assays for detection of LT. The adrenal cell system for detection of LT was more suitable than the CHO assay for processing large numbers of specimens because of the miniculture modification of this method utilized in this study. The infant mouse method was a simple and reliable method for detecting ST.


2010 ◽  
Vol 138 (5) ◽  
pp. S-582
Author(s):  
Sandra C. Kim ◽  
Susan L. Tonkonogy ◽  
Ward Jarvis ◽  
R. Balfour Sartor ◽  
James P. Nataro

2008 ◽  
Vol 15 (8) ◽  
pp. 1194-1198 ◽  
Author(s):  
Jose Flores ◽  
Herbert L. DuPont ◽  
Stephanie A. Lee ◽  
Jaime Belkind-Gerson ◽  
Mercedes Paredes ◽  
...  

ABSTRACT Up to 60% of U.S. visitors to Mexico develop traveler's diarrhea (TD), mostly due to enterotoxigenic Escherichia coli (ETEC) strains that produce heat-labile (LT) and/or heat-stable (ST) enterotoxins. Distinct single-nucleotide polymorphisms (SNPs) within the interleukin-10 (IL-10) promoter have been associated with high, intermediate, or low production of IL-10. We conducted a prospective study to investigate the association of SNPs in the IL-10 promoter and the occurrence of TD in ETEC LT-exposed travelers. Sera from U.S. travelers to Mexico collected on arrival and departure were studied for ETEC LT seroconversion by using cholera toxin as the antigen. Pyrosequencing was performed to genotype IL-10 SNPs. Stools from subjects who developed diarrhea were also studied for other enteropathogens. One hundred twenty-one of 569 (21.3%) travelers seroconverted to ETEC LT, and among them 75 (62%) developed diarrhea. Symptomatic seroconversion was more commonly seen in subjects who carried a genotype producing high levels of IL-10; it was seen in 83% of subjects with the GG genotype versus 54% of subjects with the AA genotype at IL-10 gene position −1082 (P, 0.02), in 71% of those with the CC genotype versus 33% of those with the TT genotype at position −819 (P, 0.005), and in 71% of those with the CC genotype versus 38% of those with the AA genotype at position −592 (P, 0.02). Travelers with the GCC haplotype were more likely to have symptomatic seroconversion than those with the ATA haplotype (71% versus 38%; P, 0.002). Travelers genetically predisposed to produce high levels of IL-10 were more likely to experience symptomatic ETEC TD.


2011 ◽  
Vol 55 (9) ◽  
pp. 4402-4404 ◽  
Author(s):  
Mar Solé ◽  
Cristina Pitart ◽  
Ignasi Roca ◽  
Anna Fàbrega ◽  
Pilar Salvador ◽  
...  

ABSTRACTA carbapenem-resistantEscherichia colistrain (DVR22) was recovered from a stool specimen from a patient with traveler's diarrhea who had traveled to India. Molecular screening led to the first identification of NDM-1 in Spain. TheblaNDM-1gene was located in a conjugative plasmid of ca. 300 kb that also contained theblaCTX-M-15,blaTEM-1, ΔblaDHA-1, andarmAgenes. In addition,blaNDM-1was preceded by an ISAba125insertion element only found inAcinetobacterspp.


2021 ◽  
Author(s):  
Bo Yang ◽  
Zheng Huang ◽  
Zhujun He ◽  
Yue Yue ◽  
Yonghua Zhou ◽  
...  

Enterotoxigenic Escherichia coli (ETEC) is the main bacterial cause for diarrhea among children in the developing countries and traveler’s diarrhea. In this study, mice model was used to evaluate the...


1997 ◽  
Vol 35 (9) ◽  
pp. 2279-2282 ◽  
Author(s):  
J Vila ◽  
M Vargas ◽  
J Ruiz ◽  
F Gallardo ◽  
M T Jimenez de Anta ◽  
...  

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