scholarly journals Pyridinium-substituted tetraphenylethylene salt-based photosensitizers by varying counter anions: a highly efficient photodynamic therapy for cancer cell ablation and bacterial inactivation

2020 ◽  
Vol 8 (24) ◽  
pp. 5234-5244 ◽  
Author(s):  
Wei Xiong ◽  
Lingyun Wang ◽  
Xiaoli Chen ◽  
Hao Tang ◽  
Derong Cao ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cell ◽  
Bacterial Inactivation ◽  
Highly Efficient ◽  
Cell Ablation ◽  
Photodynamic Therapy Of Cancer

A highly efficient photodynamic therapy of cancer cell ablation and bacterial inactivation by two AIEgens was reported.

Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation

2016 ◽  
Vol 4 (1) ◽  
pp. 169-176 ◽  
Author(s):  
Youyong Yuan ◽  
Shidang Xu ◽  
Chong-Jing Zhang ◽  
Ruoyu Zhang ◽  
Bin Liu
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Normal Cell ◽  
Aggregation Induced Emission ◽  
Image Guided ◽  
Cell Ablation

The currently available photosensitizers (PSs) for photodynamic therapy (PDT) can easily lead to undesirable normal cell death due to their intrinsic photo-toxicity and lack of selectivity for cancer cells.

scholarly journals Highly Efficient Drug Delivery with Gold Nanoparticle Vectors for in Vivo Photodynamic Therapy of Cancer

2008 ◽  
Vol 130 (32) ◽  
pp. 10643-10647 ◽  
Author(s):  
Yu Cheng ◽  
Anna C. Samia ◽  
Joseph D. Meyers ◽  
Irene Panagopoulos ◽  
Baowei Fei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Gold Nanoparticle ◽  
Highly Efficient ◽  
Photodynamic Therapy Of Cancer

scholarly journals Investigation of Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) Porphyrazine for Application as Photosensitizer in Photodynamic Therapy of Cancer

2008 ◽  
Vol 2008 ◽  
pp. 1-7 ◽  
Author(s):  
Keiichi Sakamoto ◽  
Eiko Ohno-Okumura ◽  
Taku Kato ◽  
Masaki Watanabe ◽  
Michael J. Cook
Keyword(s):  
Cell Culture ◽  
Photodynamic Therapy ◽  
Cancer Cell ◽  
Dimethyl Sulfate ◽  
Cell Disruption ◽  
Monochloroacetic Acid ◽  
Cyclic Voltammograms ◽  
Produce Cell ◽  
Photodynamic Therapy Of Cancer ◽  
Before And After

The phthalocyanine analogue containing nonperipheral long alkyl-substituted benzenoid rings and pyridine rings, zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) porphyrazine, was synthesized. Zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) porphyrazine reacted with dimethyl sulfate and monochloroacetic acid to produce their quaternized products and diethyl sulfate to produce the sulfo-substituted products. All quaternized and sulfo-substituted showed amphiphilic character. Identical peaks in cyclic voltammograms appeared for these products before and after quaternization. During the evaluation of zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) porphyrazine for its photodynamic therapy of cancer (PDT) efficacy by cancer cell culture, the light exposed dimethyl sulfate quaternized zinc bis(1,4-didecylbenzo)-bis(2,3-pyrido) porphyrazines in IU-002 cells produce cell disruption that can be detected as a decrease in fluorescence.

G-quadruplex/protoporphyrin IX-functionalized silver nanoconjugates for targeted cancer cell photodynamic therapy

RSC Advances ◽  
2016 ◽  
Vol 6 (99) ◽  
pp. 96942-96945 ◽  
Author(s):  
Jun Ai ◽  
Jing Li ◽  
Lu Ga ◽  
Guohong Yun ◽  
Li Xu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cell Surface ◽  
Cancer Cells ◽  
Cancer Cell ◽  
Specific Interaction ◽  
Protoporphyrin Ix ◽  
Photodynamic Therapy Of Cancer ◽  
G Quadruplex ◽  
New Type ◽  
Targeted Photodynamic Therapy

A new type of G-quadruplex/protoporphyrin IX-functionalized silver nanoconjugate was prepared and used for the targeted photodynamic therapy of cancer cells via the specific interaction between AS1411 and the nucleolin on the cell surface.

Separately doped upconversion-C60 nanoplatform for NIR imaging-guided photodynamic therapy of cancer cells

2013 ◽  
Vol 49 (31) ◽  
pp. 3224-3226 ◽  
Author(s):  
Xiaomin Liu ◽  
Min Zheng ◽  
Xianggui Kong ◽  
Youlin Zhang ◽  
Qinghui Zeng ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Highly Efficient ◽  
Nir Imaging ◽  
Photodynamic Therapy Of Cancer

A highly efficient upconversion-C60 nanoplatform was demonstrated for NIR imaging-guided photodynamic therapy of cancer.

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