3D hierarchical tubular micromotors with highly selective recognition and capture for antibiotics

2020 ◽  
Vol 8 (5) ◽  
pp. 2809-2819 ◽  
Author(s):  
Xingmei Bing ◽  
Xiaolei Zhang ◽  
Jia Li ◽  
Dickon H. L. Ng ◽  
Wenning Yang ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Scientific Community ◽  
Selective Recognition

Self-propelled micro/nanomotors attract a great deal of attention from the scientific community due to their great potential in environmental and biomedical applications.

scholarly journals Graphene-based polymeric nano-composites: an introspection into functionalization, processing techniques and biomedical applications

2019 ◽  
Vol 9 (3) ◽  
pp. 3926-3933 ◽  
Keyword(s):  
Mechanical Properties ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Polymeric Materials ◽  
Biomedical Domain ◽  
Polymeric Nanocomposites ◽  
Polymeric Matrices ◽  
Functional Capabilities ◽  
Superior Mechanical Properties ◽  
Processing Techniques

Although, there have been numerous efforts in synthesis of polymers, their mechanical properties have limited their applications. Graphene has been investigated for excellent properties such as superior mechanical properties, high thermal conductivity that has attracted the attention of scientific community to employ graphene as a filler material in polymeric matrices to form composites with multi-functional capabilities. The excellent properties possessed by Graphene has motivated users to fabricate flexible nanocomposites that can be used for applications requiring superior mechanical, chemical and thermal performances. Characteristics of both the components if explored synergistically through proper structural and interfacial organization. The investigation in this direction has resulted into combination of graphene with variety of polymeric materials and hence the development of different graphene-based nanocomposites. The present work reviews the application of graphene-based nanocomposites in the biomedical domain. With this objective, the polymeric matrices suitable for biomedical applications as well as the techniques of producing graphene polymeric nanocomposites have been discussed. Finally the application particularly in biosensing, wound healing and drug delivery system has been discussed.

scholarly journals The Usages and Potential Uses of Alginate for Healthcare Applications

2021 ◽  
Vol 8 ◽  
Author(s):  
M. Z. I. Mollah ◽  
H. M. Zahid ◽  
Z. Mahal ◽  
Mohammad Rashed Iqbal Faruque ◽  
M. U. Khandaker
Keyword(s):  
Tissue Engineering ◽  
Human Health ◽  
Tissue Regeneration ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Active Sites ◽  
Healthcare Sector ◽  
Healthcare Applications ◽  
Bioactive Component ◽  
Cell Implantation

Due to their unique properties, alginate-based biomaterials have been extensively used to treat different diseases, and in the regeneration of diverse organs. A lot of research has been done by the different scientific community to develop biofilms for fulfilling the need for sustainable human health. The aim of this review is to hit upon a hydrogel enhancing the scope of utilization in biomedical applications. The presence of active sites in alginate hydrogels can be manipulated for managing various non-communicable diseases by encapsulating, with the bioactive component as a potential site for chemicals in developing drugs, or for delivering macromolecule nutrients. Gels are accepted for cell implantation in tissue regeneration, as they can transfer cells to the intended site. Thus, this review will accelerate advanced research avenues in tissue engineering and the potential of alginate biofilms in the healthcare sector.

Biomedical Applications of Clay

2013 ◽  
Vol 66 (11) ◽  
pp. 1315 ◽  
Author(s):  
Wojciech Chrzanowski ◽  
Sally Yunsun Kim ◽  
Ensanya Ali Abou Neel
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Clay Nanocomposites ◽  
Structural Flexibility ◽  
Small Particle Size ◽  
Composition And Structure ◽  
Scope Of Application ◽  
Clay Layers

Traditional applications of clay mineral mainly revolved around cosmetics and industrial products, but their scope of application is continuously expanding into pharmaceutics including drug delivery and tissue engineering. The interest in clays amongst the scientific community has increased dramatically in recent years due to its composition and structure which can be easily modified to serve different purposes. Largely due to structural flexibility and its small particle size, clay nanostructure can be modified to tune rheological and mechanical properties, and can entrap moisture to suit a particular application. Additionally, interest in the synthesis of polymer-clay nanocomposites in tissue engineering is growing as it is cheap, easily available, and environmentally-friendly. The structure of clay allows the interclaysion of different biomolecules between the clay layers. These biomolecules can be released in a controlled manner which can be utilised in drug delivery and cosmetic applications.

scholarly journals Functional Mesoporous Silica Nanocomposites: Biomedical applications and Biosafety.

2019 ◽  
Vol 20 (4) ◽  
pp. 929 ◽  
Author(s):  
Rafael R. Castillo ◽  
María Vallet-Regí
Keyword(s):  
Chemical Composition ◽  
Mesoporous Silica ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Coating Material ◽  
Present Review ◽  
Silica Nanocomposites ◽  
Functional Composites ◽  
The Creation ◽  
New Generation

The rise and development of nanotechnology has enabled the creation of a wide number of systems with new and advantageous features to treat cancer. However, in many cases, the lone application of these new nanotherapeutics has proven not to be enough to achieve acceptable therapeutic efficacies. Hence, to avoid these limitations, the scientific community has embarked on the development of single formulations capable of combining functionalities. Among all possible components, silica—either solid or mesoporous—has become of importance as connecting and coating material for these new-generation therapeutic nanodevices. In the present review, the most recent examples of fully inorganic silica-based functional composites are visited, paying particular attention to those with potential biomedical applicability. Additionally, some highlights will be given with respect to their possible biosafety issues based on their chemical composition.

scholarly journals Applications and Nanotoxicity of Carbon Nanotubes and Graphene in Biomedicine

2012 ◽  
Vol 2012 ◽  
pp. 1-19 ◽  
Author(s):  
Caitlin Fisher ◽  
Amanda E. Rider ◽  
Zhao Jun Han ◽  
Shailesh Kumar ◽  
Igor Levchenko ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanostructures ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Research Progress ◽  
Great Promise ◽  
Carbon Structures ◽  
Safety And Toxicity ◽  
Therapeutic Tools ◽  
Biomedical Fields

Owing to their unique mechanical, electrical, optical, and thermal properties, carbon nanostructures including carbon nanotubes and graphenes show great promise for advancing the fields of biology and medicine. Many reports have demonstrated the promise of these carbon nanostructures and their hybrid structures (composites with polymers, ceramics, and metal nanoparticles, etc.) for a variety of biomedical areas ranging from biosensing, drug delivery, and diagnostics, to cancer treatment, tissue engineering, and bioterrorism prevention. However, the issue of the safety and toxicity of these carbon nanostructures, which is vital to their use as diagnostic and therapeutic tools in biomedical fields, has not been completely resolved. This paper aims to provide a summary of the features of carbon nanotube and graphene-based materials and current research progress in biomedical applications. We also highlight the current opinions within the scientific community on the toxicity and safety of these carbon structures.

scholarly journals Antibody-Conjugated Nanoparticles for Biomedical Applications

2009 ◽  
Vol 2009 ◽  
pp. 1-24 ◽  
Author(s):  
Manuel Arruebo ◽  
Mónica Valladares ◽  
África González-Fernández
Keyword(s):  
Immune System ◽  
Physicochemical Properties ◽  
Thermal Imaging ◽  
Biomedical Applications ◽  
Drug Carrier ◽  
Diagnostic Procedures ◽  
Selective Recognition ◽  
Magnetic Characteristics ◽  
Recent Developments ◽  
Hybrid Product

Nanoscience and Nanotechnology have found their way into the fields of Biotechnology and Medicine. Nanoparticles by themselves offer specific physicochemical properties that they do not exhibit in bulk form, where materials show constant physical properties regardless of size. Antibodies are nanosize biological products that are part of the specific immune system. In addition to their own properties as pathogens or toxin neutralizers, as well as in the recruitment of immune elements (complement, improving phagocytosis, cytotoxicity antibody dependent by natural killer cells, etc.), they could carry several elements (toxins, drugs, fluorochroms, or even nanoparticles, etc.) and be used in several diagnostic procedures, or even in therapy to destroy a specific target. The conjugation of antibodies to nanoparticles can generate a product that combines the properties of both. For example, they can combine the small size of nanoparticles and their special thermal, imaging, drug carrier, or magnetic characteristics with the abilities of antibodies, such as specific and selective recognition. The hybrid product will show versatility and specificity. In this review, we analyse both antibodies and nanoparticles, focusing especially on the recent developments for antibody-conjugated nanoparticles, offering the researcher an overview of the different applications and possibilities of these hybrid carriers.

scholarly journals Perceptions and Misconceptions in Molecular Recognition: Key Factors in Self-Assembling Multivalent (SAMul) Ligands/Polyanions Selectivity

Molecules ◽  
2020 ◽  
Vol 25 (4) ◽  
pp. 1003
Author(s):  
Domenico Marson ◽  
Erik Laurini ◽  
Suzana Aulic ◽  
Maurizio Fermeglia ◽  
Sabrina Pricl
Keyword(s):  
Gene Delivery ◽  
Molecular Recognition ◽  
Nucleic Acids ◽  
Biomedical Applications ◽  
Cell Membranes ◽  
Selective Recognition ◽  
Key Factors ◽  
Self Assembling ◽  
Self Assembled ◽  
Critical Aspects

Biology is dominated by polyanions (cell membranes, nucleic acids, and polysaccharides just to name a few), and achieving selective recognition between biological polyanions and synthetic systems currently constitutes a major challenge in many biomedical applications, nanovectors-assisted gene delivery being a prime example. This review work summarizes some of our recent efforts in this field; in particular, by using a combined experimental/computation approach, we investigated in detail some critical aspects in self-assembled nanomicelles and two major polyanions—DNA and heparin.

scholarly journals Overview on the Antimicrobial Activity and Biocompatibility of Sputtered Carbon-Based Coatings

Processes ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 1428
Author(s):  
Isabel Carvalho ◽  
Lisa Rodrigues ◽  
Maria José Lima ◽  
Sandra Carvalho ◽  
Sandra M. A. Cruz
Keyword(s):  
Mechanical Properties ◽  
Medical Devices ◽  
Biofilm Formation ◽  
Biomedical Applications ◽  
Scientific Community ◽  
Chemical Elements ◽  
Water Remediation ◽  
Hazardous Chemical ◽  
Real Risk ◽  
Carbon Based

Due to their outstanding properties, carbon-based structures have received much attention from the scientific community. Their applications are diverse and include use in coatings on self-lubricating systems for anti-wear situations, thin films deposited on prosthetic elements, catalysis structures, or water remediation devices. From these applications, the ones that require the most careful testing and improvement are biomedical applications. The biocompatibility and antibacterial issues of medical devices remain a concern, as several prostheses still fail after several years of implantation and biofilm formation remains a real risk to the success of a device. Sputtered deposition prevents the introduction of hazardous chemical elements during the preparation of coatings, and this technique is environmentally friendly. In addition, the mechanical properties of C-based coatings are remarkable. In this paper, the latest advances in sputtering methods and biocompatibility and antibacterial action for diamond-based carbon (DLC)-based coatings are reviewed and the greater outlook is then discussed.

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