Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery

Nanoscale ◽  
2018 ◽  
Vol 10 (35) ◽  
pp. 16848-16856 ◽  
Author(s):  
Fatemeh Zabihi ◽  
Patrick Graff ◽  
Fabian Schumacher ◽  
Burkhard Kleuser ◽  
Sarah Hedtrich ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Penetration Enhancers ◽  
High Loading ◽  
Loading Capacity ◽  
Biocompatible Polymer ◽  
Dermal Drug Delivery

Due to the low cutaneous bioavailability of tacrolimus (TAC), penetration enhancers are used to improve its penetration into the skin.

Metal–organic frameworks: a universal strategy towards super-elastic hydrogels

2019 ◽  
Vol 10 (18) ◽  
pp. 2263-2272 ◽  
Author(s):  
Huaizhi Liu ◽  
Hao Peng ◽  
Yumeng Xin ◽  
Jiuyang Zhang
Keyword(s):  
Drug Delivery ◽  
Mechanical Performance ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
High Loading ◽  
Loading Capacity ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

We reported for the first time using metal–organic framework (MOF) nanoparticles as effective nanofillers to significantly enhance the mechanical performance of hydrogels. The MOF hydrogels have been developed for drug delivery materials with high loading capacity and much extended drug releasing profiles.

scholarly journals Bio-orthogonal triazolinedione (TAD) crosslinked protein nanocapsules affect protein adsorption and cell interaction

2020 ◽  
Vol 11 (23) ◽  
pp. 3821-3830 ◽  
Author(s):  
Marie-Luise Frey ◽  
Johanna Simon ◽  
Maximilian Brückner ◽  
Volker Mailänder ◽  
Svenja Morsbach ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Click Chemistry ◽  
Protein Adsorption ◽  
Drug Delivery Systems ◽  
Cell Interaction ◽  
Delivery Systems ◽  
High Loading ◽  
Loading Capacity ◽  
Low Toxicity

Albumin-based protein nanocarriers obtained by TAD click chemistry have been widely exploited as drug delivery systems, since they show excellent degradability, low toxicity, but at the same time provide high loading capacity and relevant uptake into cells.

ZIF-67@Co-LDH yolk–shell spheres with micro-/meso-porous structures as vehicles for drug delivery

2019 ◽  
Vol 6 (11) ◽  
pp. 3140-3145 ◽  
Author(s):  
Liyong Chen ◽  
Jinfeng Wang ◽  
Xiaoshuang Shen ◽  
Xuezhao Li ◽  
Chunying Duan
Keyword(s):  
Drug Delivery ◽  
High Loading ◽  
Loading Capacity ◽  
Porous Structures ◽  
Delivery Time

The encapsulated R6G molecules in ZIF-67@Co-LDH yolk–shell heterostructures are released with high loading capacity and long delivery time.

Fe3O4@nanogel via UOx/HRP initiated surface polymerization for pH sensitive drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (58) ◽  
pp. 53170-53174 ◽  
Author(s):  
Qing Wu ◽  
Zhaoqi Wang ◽  
Haixia Zhang ◽  
Rongrong Zhu ◽  
Shilong Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Free Radical ◽  
Drug Release ◽  
Radical Polymerization ◽  
High Loading ◽  
Core Shell ◽  
Loading Capacity ◽  
Ph Responsive ◽  
Surface Polymerization ◽  
New Strategy

This study describes a new strategy to fabricate core–shell nanogels by surface free-radical polymerization initiated by the cascade reaction of UOx and HRP, which showed excellent biocompatible, high loading capacity and pH-responsive drug release.

A combined experimental and computational study of novel nanocage-based metal–organic frameworks for drug delivery

2015 ◽  
Vol 44 (44) ◽  
pp. 19370-19382 ◽  
Author(s):  
Jian-Qiang Liu ◽  
Xue-Feng Li ◽  
Chu-Ying Gu ◽  
Júlio C. S. da Silva ◽  
Amanda L. Barros ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Slow Release ◽  
Computational Study ◽  
Metal Organic Frameworks ◽  
High Loading ◽  
Loading Capacity ◽  
Metal Organic

Experimental and computational characterization of three novel metal organic frameworks (MOFs) with high loading capacity for adsorption and slow release of the drug 5-fluoracil.

Sign in / Sign up

Export Citation Format

Share Document