Metal–organic frameworks: a universal strategy towards super-elastic hydrogels

2019 ◽  
Vol 10 (18) ◽  
pp. 2263-2272 ◽  
Author(s):  
Huaizhi Liu ◽  
Hao Peng ◽  
Yumeng Xin ◽  
Jiuyang Zhang
Keyword(s):  
Drug Delivery ◽  
Mechanical Performance ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
High Loading ◽  
Loading Capacity ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

We reported for the first time using metal–organic framework (MOF) nanoparticles as effective nanofillers to significantly enhance the mechanical performance of hydrogels. The MOF hydrogels have been developed for drug delivery materials with high loading capacity and much extended drug releasing profiles.

scholarly journals Recent Developments in the Synthesis and Applications of Metal Organic Framework: A Concise Review

2021 ◽  
Vol 33 (5) ◽  
pp. 956-962
Author(s):  
Chandan Adhikari ◽  
Rehana Farooq
Keyword(s):  
Drug Delivery ◽  
Porous Materials ◽  
Electrochemical Sensors ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Inorganic Materials ◽  
Synthetic Methods ◽  
Concise Review ◽  
Metal Organic ◽  
Organic Framework

Metal organic frameworks (MOFs) are one of those compounds which have drawn attention in various applications due to their several interesting properties like tunable shape, size, pore size, easy functionalization, high surface area, pore volume, etc. Metal organic frameworks due to their uniform structures, tunable porosity, wide variety and stability on various topology, geometry, dimension and chemical functions of the molecular network give a remarkable structural diversity in comparison to other porous materials. This enables scientists to handle numerous framework structures, porosity and functionality effectively. The unique structural architecture and tunable properties of MOF’s makes them an interesting hybrid material consisting of organic and inorganic materials. MOF can be randomly constructed like Lego bricks and superior in terms of versatility in comparisson to other porous materials. A number of MOFs containing a wide variety of metal e.g. zinc, copper, iron, aluminium, magnesium, chromium, zirconium, gadolinium, manganese are gaining rapid growth in commercial markets for gas storage, adsorption, separation and catalytic applications. This concise review emphasizes various synthetic methods e.g. solvothermal process, hydrothermal synthesis, electrochemical synthesis, microwave synthesis, sonochemical synthesis, mechanochemical synthesis, of metal organic framework developed in the last few decades. It also addresses various applications of metal organic framework e.g. hydrogen storage, gas adsorption, drug delivery systems and bioimaging agents, biocatalysts, biosensors, electrochemical sensors, etc. It also comments on various challenges and futuristic applications of metal organic frameworks in various field e.g. liquid wate management, gaseous waste management, sunlight assisted catalysis, water purification, building materials, electronic devices, battery technologies, targeted drug delivery, solar cells, etc. of science and technology in coming decades.

Progress of Stimuli-Responsive Nanoscale Metal Organic Frameworks as Controlled Drug Delivery Systems

2020 ◽  
Vol 17 ◽  
Author(s):  
Ailing Feng ◽  
Yanni Wang ◽  
Jinzi Ding ◽  
Rong Xu ◽  
Xiaodong Li
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Controlled Drug Delivery ◽  
Delivery Systems ◽  
Stimuli Responsive ◽  
Direct Assembly ◽  
Metal Organic ◽  
Organic Framework

Background: Development of controlled drug delivery systems can improve the pharmacokinetic characteristics of drug molecules in the human body, thereby significantly improving the utilization rate of drugs and reducing toxicity and side effects caused by high concentrations of drugs, which can occur when delivery is not controlled. Metal organic frameworks are a new class of very promising crystalline microporous materials, especially when the size is reduced to the nanometer range. Metal organic frameworks exhibit large specific surface areas, tunable compositions, and easy functionalization. In recent years, increasing number of studies have reported the remarkable advances in multifunctional nanoscale metal organic frameworks in drug delivery. Objective: Review the latest research involving advances in stimuli-responsive nanoscale metal organic frameworks as drug delivery systems in controlled-release drugs. Discussion: We first introduce the two main strategies associated with nanoscale metal organic frameworks used in drug loading: direct assembly and post-encapsulation. We next focus on the latest discoveries of nanoscale metal organic framework-based stimulus response systems for drug delivery, including pH, magnetics, light, ion, temperature, and other stimuli, as well as multiple stimulus-responsive drug delivery systems. Finally, we discuss the challenges and future development directions of nanoscale metal organic framework-based controlled drug release.

scholarly journals Framework disorder and its effect on selective hysteretic sorption of a T-shaped azole-based metal–organic framework

IUCrJ ◽  
2019 ◽  
Vol 6 (1) ◽  
pp. 85-95 ◽  
Author(s):  
Sujuan Wang ◽  
Zhang-Wen Wei ◽  
Jianyong Zhang ◽  
Long Jiang ◽  
Dingxin Liu ◽  
...  
Keyword(s):  
Room Temperature ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Structural Disorder ◽  
Gas Sorption ◽  
Temperature Dependent ◽  
Disordered Structure ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

Metal–organic frameworks with highly ordered porosity have been studied extensively. In this paper, the effect of framework (pore) disorder on the gas sorption of azole-based isoreticular Cu(II) MOFs with rtl topology and characteristic 1D tubular pore channels is investigated for the first time. In contrast to other isoreticular rtl metal–organic frameworks, the Cu(II) metal–organic framework based on 5-(1H-imidazol-1-yl)isophthalate acid has a crystallographically identifiable disordered framework without open N-donor sites. The framework provides a unique example for investigating the effect of pore disorder on gas sorption that can be systematically evaluated. It exhibits remarkable temperature-dependent hysteretic CO2 sorption up to room temperature, and shows selectivity of CO2 over H2, CH4 and N2 at ambient temperature. The unique property of the framework is its disordered structure featuring distorted 1D tubular channels and DMF-guest-remediated defects. The results imply that structural disorder (defects) may play an important role in the modification of the performance of the material.

Metal organic framework derived Nb2O5@C nanoparticles grown on reduced graphene oxide for high-energy lithium ion capacitors

2019 ◽  
Vol 55 (18) ◽  
pp. 2692-2695 ◽  
Author(s):  
Xinyan Jiao ◽  
Qingli Hao ◽  
Xifeng Xia ◽  
Zongdeng Wu ◽  
Wu Lei
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Lithium Ion ◽  
High Energy ◽  
Reduced Graphene ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

For the first time, M-Nb2O5@C/rGO composites are fabricated by annealing the precursor of GO supported Nb-metal organic frameworks.

Silver nanoparticles prepared by gamma irradiation across metal–organic framework templates

RSC Advances ◽  
2015 ◽  
Vol 5 (14) ◽  
pp. 10707-10715 ◽  
Author(s):  
Li He ◽  
Ludovic F. Dumée ◽  
Dan Liu ◽  
Leonora Velleman ◽  
Fenghua She ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Gamma Irradiation ◽  
Room Temperature ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Single Step ◽  
Metal Organic ◽  
First Time ◽  
Organic Framework

In this study, we demonstrate for the first time the successful fabrication of well-dispersed ultrafine silver nanoparticles inside metal–organic frameworks through a single step gamma irradiation at room temperature.

Ultra-thin metal-organic framework nanosheets for chemo-photodynamic synergistic therapy

2021 ◽  
Author(s):  
Rui Zeng ◽  
Tingting He ◽  
Lu Lu ◽  
Ke Li ◽  
Zhong Luo ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Photodynamic Therapy ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Thin Metal ◽  
Metal Organic ◽  
Organic Framework

Synergistic therapy, such as chemo-photodynamic therapy, has been arousing because of its efficiency against cancers. Although the metal-organic frameworks have been widely studied in the field of drug delivery, the...

A scalable formation of nano-SnO2 anode derived from tin metal–organic frameworks for lithium-ion battery

RSC Advances ◽  
2015 ◽  
Vol 5 (89) ◽  
pp. 72825-72829 ◽  
Author(s):  
Zixu Sun ◽  
Can Cao ◽  
Wei-Qiang Han
Keyword(s):  
Lithium Ion Battery ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Lithium Ion ◽  
Metal Organic ◽  
Tin Metal ◽  
First Time ◽  
Organic Framework

In this work, for the first time, we synthesize a SnO2 nanomaterial through the calcination of tin metal–organic framework (MOF) precursors.

Nontoxic and renewable metal–organic framework based on α-cyclodextrin with efficient drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (86) ◽  
pp. 82977-82983 ◽  
Author(s):  
Jing-Quan Sha ◽  
Xiao-Hua Zhong ◽  
Lian-He Wu ◽  
Guo-Dong Liu ◽  
Ning Sheng
Keyword(s):  
Drug Delivery ◽  
Sustained Release ◽  
Metal Organic Framework ◽  
Drug Loading ◽  
Loading Capacity ◽  
Left Handed ◽  
Metal Organic ◽  
Organic Framework

Two new nontoxic α-CD based compounds were synthesized by different method, which contain different left-handed helix and exhibit efficient drug loading capacity and sustained release behaviors.

A combined experimental and computational study of novel nanocage-based metal–organic frameworks for drug delivery

2015 ◽  
Vol 44 (44) ◽  
pp. 19370-19382 ◽  
Author(s):  
Jian-Qiang Liu ◽  
Xue-Feng Li ◽  
Chu-Ying Gu ◽  
Júlio C. S. da Silva ◽  
Amanda L. Barros ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Slow Release ◽  
Computational Study ◽  
Metal Organic Frameworks ◽  
High Loading ◽  
Loading Capacity ◽  
Metal Organic

Experimental and computational characterization of three novel metal organic frameworks (MOFs) with high loading capacity for adsorption and slow release of the drug 5-fluoracil.

Magnetic Ordering via Itinerant Ferromagnetism in a Metal-Organic Framework

2020 ◽  
Author(s):  
Jesse Park ◽  
Brianna Collins ◽  
Lucy Darago ◽  
Tomce Runcevski ◽  
Michael Aubrey ◽  
...  
Keyword(s):  
Charge Transport ◽  
Magnetic Order ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Magnetic Ordering ◽  
Double Exchange ◽  
Itinerant Ferromagnetism ◽  
Organic Solids ◽  
Metal Organic ◽  
Organic Framework

<b>Materials that combine magnetic order with other desirable physical attributes offer to revolutionize our energy landscape. Indeed, such materials could find transformative applications in spintronics, quantum sensing, low-density magnets, and gas separations. As a result, efforts to design multifunctional magnetic materials have recently moved beyond traditional solid-state materials to metal–organic solids. Among these, metal–organic frameworks in particular bear structures that offer intrinsic porosity, vast chemical and structural programmability, and tunability of electronic properties. Nevertheless, magnetic order within metal–organic frameworks has generally been limited to low temperatures, owing largely to challenges in creating strong magnetic exchange in extended metal–organic solids. Here, we employ the phenomenon of itinerant ferromagnetism to realize magnetic ordering at <i>T</i><sub>C</sub> = 225 K in a mixed-valence chromium(II/III) triazolate compound, representing the highest ferromagnetic ordering temperature yet observed in a metal–organic framework. The itinerant ferromagnetism is shown to proceed via a double-exchange mechanism, the first such observation in any metal–organic material. Critically, this mechanism results in variable-temperature conductivity with barrierless charge transport below <i>T</i><sub>C</sub> and a large negative magnetoresistance of 23% at 5 K. These observations suggest applications for double-exchange-based coordination solids in the emergent fields of magnetoelectrics and spintronics. Taken together, the insights gleaned from these results are expected to provide a blueprint for the design and synthesis of porous materials with synergistic high-temperature magnetic and charge transport properties. </b>

Sign in / Sign up

Export Citation Format

Share Document