scholarly journals Tumor microenvironment-triggered fabrication of gold nanomachines for tumor-specific photoacoustic imaging and photothermal therapy

2017 ◽  
Vol 8 (7) ◽  
pp. 4896-4903 ◽  
Author(s):  
Zhengze Yu ◽  
Meimei Wang ◽  
Wei Pan ◽  
Hongyu Wang ◽  
Na Li ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Diagnosis And Therapy ◽  
Theranostic Agent ◽  
Tumor Selective ◽  
Dna Nanomachine

An alpha-cyclodextrin (α-CD)-based gold/DNA nanomachine was developed as a novel theranostic agent for tumor-selective diagnosis and therapy.

scholarly journals Development of tungsten bronze nanorods for redox-enhanced photoacoustic imaging-guided photothermal therapy of tumors

RSC Advances ◽  
2018 ◽  
Vol 8 (47) ◽  
pp. 26713-26719 ◽  
Author(s):  
Hongbo Gao ◽  
Xiangming Fang ◽  
Jing Xiang ◽  
Xiaohang Liu ◽  
JianPing Zhang ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Tungsten Bronze ◽  
Redox Status

Although various kinds of nanomaterials have been used as anticancer theranostics by exploiting the tumor microenvironment, relatively few nanomaterials can be efficiently activated by the tumor redox status for imaging and therapy.

Enzyme-responsive copper sulphide nanoparticles for combined photoacoustic imaging, tumor-selective chemotherapy and photothermal therapy

2013 ◽  
Vol 49 (33) ◽  
pp. 3455 ◽  
Author(s):  
Zhengbao Zha ◽  
Shuhai Zhang ◽  
Zijian Deng ◽  
Yanyan Li ◽  
Changhui Li ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Copper Sulphide ◽  
Selective Chemotherapy ◽  
Tumor Selective

scholarly journals In situ formation of pH-responsive Prussian blue for photoacoustic imaging and photothermal therapy of cancer

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18270-18276 ◽  
Author(s):  
Ming Cheng ◽  
Wei Peng ◽  
Peng Hua ◽  
Zhengrong Chen ◽  
Jia Sheng ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ph Responsive ◽  
Background Signal ◽  
Normal Tissues ◽  
Theranostic Agent ◽  
In Situ Formation

Dual pH-responsive theranostic agent reduces the background signal in photoacoustic imaging and non-specific heating of normal tissues in photothermal therapy.

Tumor microenvironment-activated NIR-II reagents for tumor imaging and therapy

2020 ◽  
Vol 8 (22) ◽  
pp. 4738-4747 ◽  
Author(s):  
Xue Zhang ◽  
Lu An ◽  
Qiwei Tian ◽  
Jiaomin Lin ◽  
Shiping Yang
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Tumor Diagnosis ◽  
Diagnosis And Treatment ◽  
Recent Advances

This review summarizes the recent advances of tumor microenvironment-activated NIR-II agents for tumor diagnosis and treatment, including smart NIR-II fluorescence imaging, photoacoustic imaging, photothermal therapy and photodynamic therapy.

scholarly journals A dual-functional benzobisthiadiazole derivative as an effective theranostic agent for near-infrared photoacoustic imaging and photothermal therapy

2016 ◽  
Vol 4 (9) ◽  
pp. 1696-1703 ◽  
Author(s):  
Shuo Huang ◽  
Paul Kumar Upputuri ◽  
Hui Liu ◽  
Manojit Pramanik ◽  
Mingfeng Wang
Keyword(s):  
Small Molecules ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Photoacoustic Signal ◽  
Colloidal Nanoparticles ◽  
Theranostic Agent ◽  
Dual Functional ◽  
Narrow Bandgap ◽  
Theranostic Agents

Colloidal nanoparticles of BBT-based narrow-bandgap small molecules as theranostic agents show a strong near-infrared photoacoustic signal and high photothermal conversion efficiency.

scholarly journals A tumor microenvironment–induced absorption red-shifted polymer nanoparticle for simultaneously activated photoacoustic imaging and photothermal therapy

2021 ◽  
Vol 7 (12) ◽  
pp. eabe3588
Author(s):  
Shulong Wang ◽  
Liangliang Zhang ◽  
Jingjin Zhao ◽  
Min He ◽  
Yong Huang ◽  
...  
Keyword(s):  
Absorption Spectrum ◽  
Tumor Microenvironment ◽  
Redox Reaction ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Imaging ◽  
Photoacoustic Imaging ◽  
Diagnosis And Treatment ◽  
Induced Absorption

Tumor microenvironment–responsive therapy has enormous application potential in the diagnosis and treatment of cancer. The glutathione (GSH) level has been shown to be significantly increased in tumor tissues. Thus, GSH can be used as an effective endogenous molecule for diagnosis and tumor microenvironment–activated therapy. In this study, we prepared a tumor microenvironment–induced, absorption spectrum red-shifted, iron-copper co-doped polyaniline nanoparticle (Fe-Cu@PANI). The Cu(II) in this nanoparticle can undergo a redox reaction with GSH in tumors. The redox reaction induces a red shift in the absorption spectrum of the Fe-Cu@PANI nanoparticles from the visible to the near-infrared region accompanying with the etching of this nanoparticle, which simultaneously activates tumor photoacoustic imaging and photothermal therapy, thereby improving the accuracy of in vivo tumor imaging and the efficiency of photothermal therapy. The nanoparticle prepared in this study has broad application prospects in the diagnosis and treatment of cancer.

PEGylated WS2Nanosheets as a Multifunctional Theranostic Agent for in vivo Dual-Modal CT/Photoacoustic Imaging Guided Photothermal Therapy

2013 ◽  
Vol 26 (12) ◽  
pp. 1886-1893 ◽  
Author(s):  
Liang Cheng ◽  
Jingjing Liu ◽  
Xing Gu ◽  
Hua Gong ◽  
Xiaoze Shi ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Theranostic Agent
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