scholarly journals In situ formation of pH-responsive Prussian blue for photoacoustic imaging and photothermal therapy of cancer

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18270-18276 ◽  
Author(s):  
Ming Cheng ◽  
Wei Peng ◽  
Peng Hua ◽  
Zhengrong Chen ◽  
Jia Sheng ◽  
...  
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ph Responsive ◽  
Background Signal ◽  
Normal Tissues ◽  
Theranostic Agent ◽  
In Situ Formation

Dual pH-responsive theranostic agent reduces the background signal in photoacoustic imaging and non-specific heating of normal tissues in photothermal therapy.

scholarly journals Precision Photothermal Therapy and Photoacoustic Imaging by In Situ Activatable Thermoplasmonics

2021 ◽  
Author(s):  
Yahua Liu ◽  
Fengye Mo ◽  
Jialing Hu ◽  
Qunying Jiang ◽  
Xiuyuan Wang ◽  
...  
Keyword(s):  
Side Effects ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Clinical Translation ◽  
Great Promise ◽  
Disease Treatment ◽  
Normal Tissues

Phototherapy holds great promise for disease treatment; however, traditional “always-on” photoagents have been restricted for clinical translation due to nonspecific response and side effects on normal tissues. Here, we show...

A photo-stable and reversible pH-responsive nano-agent based on the NIR phenazine dye for photoacoustic imaging-guided photothermal therapy

2019 ◽  
Vol 55 (73) ◽  
pp. 10940-10943 ◽  
Author(s):  
Yongchao Yan ◽  
Hao Fu ◽  
Jian Wang ◽  
Chuanrong Chen ◽  
Qi Wang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Weak Acid ◽  
Ph Responsive ◽  
Agent Based ◽  
Nir Absorption ◽  
Acid Environment

A photo-stable and reversible pH-responsive phenazine dye displayed an obvious NIR absorption in a weak acid environment of tumor. The dye assembled into nanoparticles was developed for photoacoustic imaging-guided photothermal therapy in mice.

In situ crystal growth of gold nanocrystals on upconversion nanoparticles for synergistic chemo-photothermal therapy

Nanoscale ◽  
2017 ◽  
Vol 9 (35) ◽  
pp. 12885-12896 ◽  
Author(s):  
Ruoyan Wei ◽  
Wensong Xi ◽  
Haifang Wang ◽  
Jinliang Liu ◽  
Torsten Mayr ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Photothermal Therapy ◽  
Upconversion Nanoparticles ◽  
Ph Responsive ◽  
Gold Nanocrystals

A multifunctional nanocomposite was synthesized by linking pH-responsive prodrug onto gold nanocrystals that were grown in situ on the surface of upconversion nanoparticles, which is bioimaging-guided multifunctional synergistic therapy agent.

Prussian blue-coated lanthanide-doped core/shell/shell nanocrystals for NIR-II image-guided photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (45) ◽  
pp. 22079-22088 ◽  
Author(s):  
Xin Wang ◽  
Hui Li ◽  
Feng Li ◽  
Xiaojun Han ◽  
Guanying Chen
Keyword(s):  
Prussian Blue ◽  
Photothermal Therapy ◽  
Core Shell ◽  
Image Guided ◽  
Theranostic Agent

A lanthanide-based theranostic agent for image-guided photothermal therapy.

scholarly journals Multifunctional bioactive Nd-Ca-Si glasses for fluorescence thermometry, photothermal therapy, and burn tissue repair

2020 ◽  
Vol 6 (32) ◽  
pp. eabb1311
Author(s):  
Lingling Ma ◽  
Yanling Zhou ◽  
Zhaowenbin Zhang ◽  
Yaqin Liu ◽  
Dong Zhai ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Treatment Temperature ◽  
Temperature Monitoring ◽  
Tumor Treatment ◽  
Treatment Technology ◽  
Excessive Heat ◽  
Normal Tissues ◽  
Normal Tissue Damage ◽  
Photothermal Property

Photothermal therapy (PTT), an emerging tumor treatment technology, has attracted tremendous interest, but excessive heat will cause damage to surrounding healthy tissues. Therefore, in situ temperature monitoring during PTT is of great importance to determine optimal treatment temperature and repair heat-damaged normal tissues. Here, we report the preparation of multifunctional Nd-Ca-Si silicate glasses and glass/alginate composite hydrogels that not only have photothermal property but also emit fluorescence under 808-nm laser irradiation, and its fluorescence intensity is linearly correlated with in situ temperature. With this feature, optimal PTT temperature for effective tumor treatment with minimal normal tissue damage can be obtained. In addition, because of the bioactive silicate components, the composite hydrogel has bioactivity to repair heat damage caused by PTT. This implantable multifunctional material with unique temperature monitoring, photothermal function, and wound healing bioactivity can be used for localized thermal therapy.

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