Theranostic micelles based on upconversion nanoparticles for dual-modality imaging and photodynamic therapy in hepatocellular carcinoma

Nanoscale ◽  
2018 ◽  
Vol 10 (14) ◽  
pp. 6511-6523 ◽  
Author(s):  
Yong Han ◽  
Yanli An ◽  
Gang Jia ◽  
Xihui Wang ◽  
Chen He ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Photodynamic Therapy ◽  
Therapeutic Strategies ◽  
Upconversion Nanoparticles ◽  
Curative Surgery ◽  
Dual Modality ◽  
Dual Modality Imaging

Hepatocellular carcinoma (HCC) is frequently metastatic once diagnosed and less likely to respond to curative surgery, emphasizing the need for the development of more sensitive and effective diagnostic and therapeutic strategies.

Upconversion Nanoparticles Conjugated with Gd3+-DOTA and RGD for Targeted Dual-Modality Imaging of Brain Tumor Xenografts

2013 ◽  
Vol 2 (11) ◽  
pp. 1501-1512 ◽  
Author(s):  
Jiefu Jin ◽  
Zhenhua Xu ◽  
Yue Zhang ◽  
Yan-Juan Gu ◽  
Michael Hon-Wah Lam ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Upconversion Nanoparticles ◽  
Tumor Xenografts ◽  
Dual Modality ◽  
Dual Modality Imaging

Abstract 5297: Dual-modality imaging of hepatocellular carcinoma

2011 ◽  
Author(s):  
David Corn ◽  
Jack Jesberger ◽  
Jeffrey Kolthammer ◽  
Christopher Flask ◽  
Zhenghong Lee
Keyword(s):  
Hepatocellular Carcinoma ◽  
Dual Modality ◽  
Dual Modality Imaging

Core–shell hybrid upconversion nanoparticles carrying stable nitroxide radicals as potential multifunctional nanoprobes for upconversion luminescence and magnetic resonance dual-modality imaging

Nanoscale ◽  
2015 ◽  
Vol 7 (12) ◽  
pp. 5249-5261 ◽  
Author(s):  
Chuan Chen ◽  
Ning Kang ◽  
Ting Xu ◽  
Dong Wang ◽  
Lei Ren ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Upconversion Luminescence ◽  
Upconversion Nanoparticles ◽  
Core Shell ◽  
Nitroxide Radicals ◽  
Dual Modality ◽  
Dual Modality Imaging ◽  
Stable Nitroxide

A nitroxide radicals doped SiO2 was coated on upconversion nanoparticles to generate novel UCNP@TEMPO@SiO2 nanoprobes for dual-modality imaging.

Biocompatible melanin based theranostic agent for in vivo detection and ablation of orthotopic micro-hepatocellular carcinoma

2020 ◽  
Vol 8 (15) ◽  
pp. 4322-4333
Author(s):  
Kang Chen ◽  
Qiaolin Li ◽  
Xingyang Zhao ◽  
Jinde Zhang ◽  
Haosong Ma ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Dual Modality ◽  
Theranostic Agent ◽  
Photothermal Ablation ◽  
In Vivo Detection ◽  
Therapeutic Outcomes ◽  
Dual Modality Imaging

Enhanced photoacoustic performance and therapeutic outcomes of melanin-based organic agents for dual-modality imaging and photothermal ablation of orthotopic hepatocellular carcinoma.

Construction of a near-infrared responsive upconversion nanoplatform against hypoxic tumors via NO-enhanced photodynamic therapy

Nanoscale ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 7875-7887 ◽  
Author(s):  
Ying Lan ◽  
Xiaohui Zhu ◽  
Ming Tang ◽  
Yihan Wu ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Upconversion Nanoparticles

A near-infrared (NIR) activated theranostic nanoplatform based on upconversion nanoparticles (UCNPs) is developed in order to overcome the hypoxia-associated resistance in photodynamic therapy by photo-release of NO upon NIR illumination.

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