scholarly journals iRGD Peptide-Mediated Liposomal Nanoparticles with Photoacoustic/Ultrasound Dual-Modality Imaging for Precision Theranostics Against Hepatocellular Carcinoma

2021 ◽  
Vol Volume 16 ◽  
pp. 6455-6475
Author(s):  
Huipu Li ◽  
Shasha Shi ◽  
Meng Wu ◽  
Wei Shen ◽  
Jianli Ren ◽  
...  
Author(s):  
David Corn ◽  
Jack Jesberger ◽  
Jeffrey Kolthammer ◽  
Christopher Flask ◽  
Zhenghong Lee

Nanoscale ◽  
2018 ◽  
Vol 10 (14) ◽  
pp. 6511-6523 ◽  
Author(s):  
Yong Han ◽  
Yanli An ◽  
Gang Jia ◽  
Xihui Wang ◽  
Chen He ◽  
...  

Hepatocellular carcinoma (HCC) is frequently metastatic once diagnosed and less likely to respond to curative surgery, emphasizing the need for the development of more sensitive and effective diagnostic and therapeutic strategies.


2020 ◽  
Vol 8 (15) ◽  
pp. 4322-4333
Author(s):  
Kang Chen ◽  
Qiaolin Li ◽  
Xingyang Zhao ◽  
Jinde Zhang ◽  
Haosong Ma ◽  
...  

Enhanced photoacoustic performance and therapeutic outcomes of melanin-based organic agents for dual-modality imaging and photothermal ablation of orthotopic hepatocellular carcinoma.


Theranostics ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 2161-2170 ◽  
Author(s):  
Marlène C. Hekman ◽  
Mark Rijpkema ◽  
Constantijn H. Muselaers ◽  
Egbert Oosterwijk ◽  
Christina A. Hulsbergen-Van de Kaa ◽  
...  

2015 ◽  
Vol 2 (Suppl 1) ◽  
pp. A89 ◽  
Author(s):  
Charalmpos Tsoukalas ◽  
Gautier Laurent ◽  
Gloria Jiménez Sánchez ◽  
Theodoros Tsotakos ◽  
Rana Bazzi ◽  
...  

2002 ◽  
Vol 1 (6) ◽  
pp. 449-458 ◽  
Author(s):  
Bruce H. Hasegawa ◽  
Kenneth H. Wong ◽  
Koji Iwata ◽  
William C. Barber ◽  
Andrew B. Hwang ◽  
...  

Dual-modality imaging is an in vivo diagnostic technique that obtains structural and functional information directly from patient studies in a way that cannot be achieved with separate imaging systems alone. Dual-modality imaging systems are configured by combining computed tomography (CT) with radionuclide imaging (using positron emission tomography (PET) or single-photon emission computed tomography (SPECT)) on a single gantry which allows both functional and structural imaging to be performed during a single imaging session without having the patient leave the imaging system. A SPECT/CT system developed at UCSF is being used in a study to determine if dual-modality imaging offers advantages for assessment of patients with prostate cancer using111 In-ProstaScint®, a radiolabeled antibody for the prostate-specific membrane antigen.111 In-ProstaScint® images are reconstructed using an iterative maximum-likelihood expectation-maximization (ML-EM) algorithm with correction for photon attenuation using a patient-specific map of attenuation coefficients derived from CT. The ML-EM algorithm accounts for the dual-photon nature of the111 In-labeled radionuclide, and incorporates correction for the geometric response of the radionuclide collimator. The radionuclide image then can be coregistered and overlaid in color on a grayscale CT image for improved localization of the functional information from SPECT. Radionuclide images obtained with SPECT/CT and reconstructed using ML-EM with correction for photon attenuation and collimator response improve image quality in comparison to conventional radionuclide images obtained with filtered backprojection reconstruction. These results illustrate the potential advantages of dual-modality imaging for improving the quality and the localization of radionuclide uptake for staging disease, planning treatment, and monitoring therapeutic response in patients with cancer.


2012 ◽  
Vol 163 (2) ◽  
pp. 249-255 ◽  
Author(s):  
Jaehong Key ◽  
Christy Cooper ◽  
Ah Young Kim ◽  
Deepika Dhawan ◽  
Deborah W. Knapp ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document