scholarly journals Synthesis and super-resolution imaging performance of a refractive-index-controllable microsphere superlens

2015 ◽  
Vol 3 (41) ◽  
pp. 10907-10915 ◽  
Author(s):  
Haie Zhu ◽  
Bing Yan ◽  
Shuxue Zhou ◽  
Zengbo Wang ◽  
Limin Wu
Keyword(s):  
Refractive Index ◽  
Super Resolution ◽  
Resolution Imaging ◽  
Imaging Performance

scholarly journals Controlling the non-linear emission of upconversion nanoparticles to enhance super-resolution imaging performance

Nanoscale ◽  
2020 ◽  
Vol 12 (39) ◽  
pp. 20347-20355
Author(s):  
Simone De Camillis ◽  
Peng Ren ◽  
Yueying Cao ◽  
Martin Plöschner ◽  
Denitza Denkova ◽  
...  
Keyword(s):  
Super Resolution ◽  
Upconversion Nanoparticles ◽  
Non Linear ◽  
Resolution Imaging ◽  
Imaging Performance ◽  
Luminescence Characteristics

Convenient design of fully Yb-based upconversion nanoparticles enables control of their luminescence characteristics and enhances super-resolution imaging performance.

scholarly journals Coated High-Refractive-Index Barium Titanate Glass Microspheres for Optically Trapped Microsphere Super-Resolution Microscopy: A Simulation Study

Photonics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 84
Author(s):  
Xi Liu ◽  
Song Hu ◽  
Yan Tang
Keyword(s):  
Refractive Index ◽  
Barium Titanate ◽  
Optical Trapping ◽  
Super Resolution ◽  
High Refractive Index ◽  
Trapping Efficiency ◽  
Single Beam ◽  
Imaging Performance ◽  
Super Resolution Microscopy ◽  
Optically Trapped

As water is normally used as the immersion medium in optically trapped microsphere microscopy, the high-refractive-index barium titanate glass (BTG) microsphere shows a better imaging performance than the low-index polystyrene (PS) or melamine formaldehyde (MF) microsphere, but it is difficult to be trapped by single-beam optical trapping due to its overly high refractive index. In this study, coated BTG microspheres with a PS coating have been computationally explored for the combination of optical trapping with microsphere-assisted microscopy. The PS coating thickness affects both the optical trapping efficiency and photonic nanojet (PNJ) property of the coated BTG sphere. Compared to the uncoated BTG sphere, the coated BTG sphere with a proper PS coating thickness has a highly improved trapping efficiency which enables single-beam optical trapping, and a better PNJ with a higher optical intensity Imax and a narrower full width at half maximum (FWHM) corresponding to better imaging performance. These coated BTG spheres also have an advantage in trapping efficiency and imaging performance over conventional PS and MF spheres. The coated BTG microsphere is highly desirable for optically trapped microsphere super-resolution microscopy and potentially beneficial to other research areas, such as nanoparticle detection.

scholarly journals A stable, high refractive index, switching buffer for super-resolution imaging

2018 ◽  
Author(s):  
Tobias M.P. Hartwich ◽  
Kenny Kwok Hin Chung ◽  
Lena Schroeder ◽  
Joerg Bewersdorf ◽  
Christian Soeller ◽  
...  
Keyword(s):  
Refractive Index ◽  
Super Resolution ◽  
High Refractive Index ◽  
Dye Molecules ◽  
Switching Speed ◽  
Dark State ◽  
Oxygen Scavenging ◽  
Index Matching ◽  
Improved Stability ◽  
Resolution Imaging

AbstractdSTORM super-resolution imaging relies on switching buffers to enable dye molecules to enter and exit a metastable dark state. Current buffers have a very limited shelf life of approximately 1 day and poorly match sample refractive index, impacting negatively on measurement reproducibility and image fidelity. We present a buffer based on chemical, rather than enzymatic, oxygen scavenging which exhibits dramatically improved stability, switching speed, contrast, and index matching.

A polymer index-matched to water enables diverse applications in fluorescence microscopy

Lab on a Chip ◽  
2021 ◽  
Vol 21 (8) ◽  
pp. 1549-1562
Author(s):  
Xiaofei Han ◽  
Yijun Su ◽  
Hamilton White ◽  
Kate M. O'Neill ◽  
Nicole Y. Morgan ◽  
...  
Keyword(s):  
Refractive Index ◽  
Fluorescence Microscopy ◽  
Biological Samples ◽  
Super Resolution ◽  
Resolution Imaging

Diffraction-limited and super-resolution imaging of biological samples using refractive-index matched polymers in microdevices.

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