A highly selective colorimetric Cys sensor based on core-substituted naphthalene diimides

RSC Advances ◽  
2015 ◽  
Vol 5 (122) ◽  
pp. 100697-100701 ◽  
Author(s):  
Sharad R. Bobe ◽  
Rajesh S. Bhosale ◽  
Santosh P. Goskulwad ◽  
Avinash L. Puyad ◽  
Sheshanath V. Bhosale ◽  
...  

This study presents the core-substituted naphthalenediimide based probe 1 for the selective detection of cysteine via photoinduced electron transfer (PET) effect.

2016 ◽  
Vol 52 (51) ◽  
pp. 7982-7985 ◽  
Author(s):  
Lijuan Liang ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Liancheng Zhao ◽  
Xianshun Zeng

A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl.


The Analyst ◽  
2014 ◽  
Vol 139 (12) ◽  
pp. 2986-2989 ◽  
Author(s):  
Jiyoung Kim ◽  
Youngmi Kim

A water-soluble sulfonate-BODIPY dye1was developed for the selective detection of HOCl/OCl−in aqueous buffer solution. The probe, which displays extremely weak fluorescence owing to efficient photoinduced electron transfer (PeT) from the pendant catechol donor, responds to HOCl/OCl−through a dramatic enhancement of its fluorescence intensity.


The Analyst ◽  
2014 ◽  
Vol 139 (19) ◽  
pp. 4794-4798 ◽  
Author(s):  
Pinkesh G. Sutariya ◽  
Alok Pandya ◽  
Anand Lodha ◽  
Shobhana K. Menon

A novel photoinduced electron transfer (PET) based substituted calix[4]arene fluoroionophore has been used for the selective recognition of tryptophan (l-Trp) and histidine (l-His) by emission spectra.


RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 84319-84325 ◽  
Author(s):  
Santosh Chemate ◽  
Yogesh Erande ◽  
Dhanraj Mohbiya ◽  
Nagaiyan Sekar

A new acridine based photoinduced electron transfer based fluorescent chemosensor for the detection of nitroaromatic compounds is reported. The probe exhibited high selectivity and sensitivity for the detection of picric acid over trivial explosive in CH3OH.


2020 ◽  
Author(s):  
Rishikesh Kulkarni ◽  
Anneliese Gest ◽  
Chun Kei Lam ◽  
Benjamin Raliski ◽  
Feroz James ◽  
...  

<p>High signal-to-noise optical voltage indicators will enable simultaneous interrogation of membrane potential in large ensembles of neurons. However, design principles for voltage sensors with high sensitivity and brightness remain elusive, limiting the applicability of voltage imaging. In this paper, we use molecular dynamics (MD) simulations and density functional theory (DFT) calculations to guide the design of a bright and sensitive green-fluorescent voltage-sensitive fluorophore, or VoltageFluor (VF dye), that uses photoinduced electron transfer (PeT) as a voltage-sensing mechanism. MD simulations predict an 11% increase in sensitivity due to membrane orientation, while DFT calculations predict an increase in fluorescence quantum yield, but a decrease in sensitivity due to a decrease in rate of PeT. We confirm these predictions by synthesizing a new VF dye and demonstrating that it displays the expected improvements by doubling the brightness and retaining similar sensitivity to prior VF dyes. Combining theoretical predictions and experimental validation has resulted in the synthesis of the highest signal-to-noise green VF dye to date. We use this new voltage indicator to monitor the electrophysiological maturation of human embryonic stem cell-derived medium spiny neurons. </p>


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