A unique fluorescence biosensor for selective detection of tryptophan and histidine

The Analyst ◽  
2014 ◽  
Vol 139 (19) ◽  
pp. 4794-4798 ◽  
Author(s):  
Pinkesh G. Sutariya ◽  
Alok Pandya ◽  
Anand Lodha ◽  
Shobhana K. Menon
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
Emission Spectra ◽  
Selective Recognition ◽  
Selective Detection ◽  
Fluorescence Biosensor

A novel photoinduced electron transfer (PET) based substituted calix[4]arene fluoroionophore has been used for the selective recognition of tryptophan (l-Trp) and histidine (l-His) by emission spectra.

A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells

2016 ◽  
Vol 52 (51) ◽  
pp. 7982-7985 ◽  
Author(s):  
Lijuan Liang ◽  
Chang Liu ◽  
Xiaojie Jiao ◽  
Liancheng Zhao ◽  
Xianshun Zeng
Keyword(s):  
Electron Transfer ◽  
Acridine Orange ◽  
Fluorescent Probe ◽  
Photoinduced Electron Transfer ◽  
Living Cells ◽  
Selective Detection

A probe based on the phenothiazine–acridine orange conjugate (Ptz–AO) has been designed and synthesized for the sensitive and selective detection of HOCl.

A water-soluble sulfonate-BODIPY based fluorescent probe for selective detection of HOCl/OCl−in aqueous media

The Analyst ◽  
2014 ◽  
Vol 139 (12) ◽  
pp. 2986-2989 ◽  
Author(s):  
Jiyoung Kim ◽  
Youngmi Kim
Keyword(s):  
Electron Transfer ◽  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Photoinduced Electron Transfer ◽  
Aqueous Media ◽  
Water Soluble ◽  
Selective Detection ◽  
Buffer Solution ◽  
Aqueous Buffer ◽  
Aqueous Buffer Solution

A water-soluble sulfonate-BODIPY dye1was developed for the selective detection of HOCl/OCl−in aqueous buffer solution. The probe, which displays extremely weak fluorescence owing to efficient photoinduced electron transfer (PeT) from the pendant catechol donor, responds to HOCl/OCl−through a dramatic enhancement of its fluorescence intensity.

A highly selective colorimetric Cys sensor based on core-substituted naphthalene diimides

RSC Advances ◽  
2015 ◽  
Vol 5 (122) ◽  
pp. 100697-100701 ◽  
Author(s):  
Sharad R. Bobe ◽  
Rajesh S. Bhosale ◽  
Santosh P. Goskulwad ◽  
Avinash L. Puyad ◽  
Sheshanath V. Bhosale ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
Selective Detection ◽  
The Core ◽  
Naphthalene Diimides

This study presents the core-substituted naphthalenediimide based probe 1 for the selective detection of cysteine via photoinduced electron transfer (PET) effect.

Acridine derivative as a “turn on” probe for selective detection of picric acid via PET deterrence

RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 84319-84325 ◽  
Author(s):  
Santosh Chemate ◽  
Yogesh Erande ◽  
Dhanraj Mohbiya ◽  
Nagaiyan Sekar
Keyword(s):  
Electron Transfer ◽  
Photoinduced Electron Transfer ◽  
High Selectivity ◽  
Picric Acid ◽  
Nitroaromatic Compounds ◽  
Fluorescent Chemosensor ◽  
Selective Detection ◽  
Acridine Derivative ◽  
Turn On

A new acridine based photoinduced electron transfer based fluorescent chemosensor for the detection of nitroaromatic compounds is reported. The probe exhibited high selectivity and sensitivity for the detection of picric acid over trivial explosive in CH3OH.

Computationally Assisted Design of High Signal-to-Noise Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes

2020 ◽  
Author(s):  
Rishikesh Kulkarni ◽  
Anneliese Gest ◽  
Chun Kei Lam ◽  
Benjamin Raliski ◽  
Feroz James ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Dft Calculations ◽  
Photoinduced Electron Transfer ◽  
Density Functional ◽  
Embryonic Stem ◽  
High Sensitivity ◽  
Md Simulations ◽  
High Signal ◽  
Signal To Noise ◽  
Green Fluorescent

<p>High signal-to-noise optical voltage indicators will enable simultaneous interrogation of membrane potential in large ensembles of neurons. However, design principles for voltage sensors with high sensitivity and brightness remain elusive, limiting the applicability of voltage imaging. In this paper, we use molecular dynamics (MD) simulations and density functional theory (DFT) calculations to guide the design of a bright and sensitive green-fluorescent voltage-sensitive fluorophore, or VoltageFluor (VF dye), that uses photoinduced electron transfer (PeT) as a voltage-sensing mechanism. MD simulations predict an 11% increase in sensitivity due to membrane orientation, while DFT calculations predict an increase in fluorescence quantum yield, but a decrease in sensitivity due to a decrease in rate of PeT. We confirm these predictions by synthesizing a new VF dye and demonstrating that it displays the expected improvements by doubling the brightness and retaining similar sensitivity to prior VF dyes. Combining theoretical predictions and experimental validation has resulted in the synthesis of the highest signal-to-noise green VF dye to date. We use this new voltage indicator to monitor the electrophysiological maturation of human embryonic stem cell-derived medium spiny neurons. </p>

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