scholarly journals Virus-mimicking nano-constructs as a contrast agent for near infrared photoacoustic imaging

Nanoscale ◽  
2013 ◽  
Vol 5 (5) ◽  
pp. 1772 ◽  
Author(s):  
Sharad Gupta ◽  
Muhammad R. Chatni ◽  
Ayala L. N. Rao ◽  
Valentine I. Vullev ◽  
Lihong V. Wang ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Near Infrared ◽  
Photoacoustic Imaging

scholarly journals Polypyrrole–methylene blue nanoparticles as a single multifunctional nanoplatform for near-infrared photo-induced therapy and photoacoustic imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (56) ◽  
pp. 35027-35037 ◽  
Author(s):  
Thi Tuong Vy Phan ◽  
Subramaniyan Bharathiraja ◽  
Van Tu Nguyen ◽  
Madhappan Santha Moorthy ◽  
Panchanathan Manivasagan ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Contrast Agent ◽  
Near Infrared ◽  
Photoacoustic Imaging

A novel contrast agent with broad NIR absorbing properties for combined photo-induced therapy and photoacoustic imaging.

scholarly journals Photoacoustic molecular imaging using combined acupuncture and gold nanorods as a composite contrast agent

2019 ◽  
Vol 12 (03) ◽  
pp. 1941004
Author(s):  
Dan Wu ◽  
Xinxin Zhang ◽  
Jian Rong ◽  
Huabei Jiang
Keyword(s):  
Contrast Agent ◽  
Contrast Enhancement ◽  
Mouse Brain ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Local Concentration ◽  
Quantitative Results ◽  
Zusanli Acupoint

In this study, we developed a novel photoacoustic imaging technique based on poly (ethyleneglycol)-coated (PEGylated) gold nanorods (PEG-GNRs) (as the contrast agent) combined with traditional Chinese medicine (TCM) acupuncture (as the auxiliary method) for quantitatively monitoring contrast enhancement in the vasculature of a mouse brain in vivo. This study takes advantage of the strong near-infrared absorption (peak at [Formula: see text][Formula: see text]nm) of GNRs and the ability to adjust the hemodynamics of acupuncture. Experimental results show that photoacoustic tomography (PAT) successfully reveals the optical absorption variation of the vasculature of the mouse brain in response to intravenous administration of GNRs and acupuncture at the Zusanli acupoint (ST36) both individually and combined. The quantitative measurement of contrast enhancement indicates that the composite contrast agents (integration of acupuncture and GNRs) would greatly enhance the photoacoustic imaging contrast. The quantitative results also have the potential to estimate the local concentration of GNRs and even the real-time effects of acupuncture.

scholarly journals Near-infrared light-responsive liposomal contrast agent for photoacoustic imaging and drug release applications

2016 ◽  
Vol 22 (4) ◽  
pp. 041007 ◽  
Author(s):  
Kathyayini Sivasubramanian ◽  
Malathi Mathiyazhakan ◽  
Christian Wiraja ◽  
Paul Kumar Upputuri ◽  
Chenjie Xu ◽  
...  
Keyword(s):  
Drug Release ◽  
Contrast Agent ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Infrared Light ◽  
Near Infrared Light

Naphthalene-fused BODIPY near-infrared dye as a stable contrast agent for in vivo photoacoustic imaging

2016 ◽  
Vol 52 (77) ◽  
pp. 11504-11507 ◽  
Author(s):  
Yong Ni ◽  
Ravi K. Kannadorai ◽  
Juanjuan Peng ◽  
Sidney W.-K. Yu ◽  
Young-Tae Chang ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Near Infrared Dye

Naphthalene-fused BODIPY near infrared dye (Na-BD) was synthesized and used as a stable contrast agent for in vivo photoacoustic imaging.

Pyrazino[2,3-g]quinoxaline-Based Nanoparticles as Near-Infrared Phototheranostic Agents for Efficient Photoacoustic-Imaging-Guided Photothermal Therapy

2021 ◽  
Vol 4 (2) ◽  
pp. 2019-2029
Author(s):  
Li-Peng Zhang ◽  
Lin Kang ◽  
Xianqiang Li ◽  
Shiyang Liu ◽  
Tianlong Liu ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging

Ambient Oxygen-Doped Conjugated Polymer for pH-Activatable Aggregation-Enhanced Photoacoustic Imaging in the Second Near-Infrared Window

2021 ◽  
Vol 93 (6) ◽  
pp. 3189-3195
Author(s):  
Jiayingzi Wu ◽  
Liyan You ◽  
Saadia T. Chaudhry ◽  
Jiazhi He ◽  
Ji-Xin Cheng ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Ambient Oxygen ◽  
Infrared Window

scholarly journals Exploiting cyanine dye J-aggregates/monomer equilibrium in hydrophobic protein pockets for efficient multi-step phototherapy: An innovative concept for smart nanotheranostics

Nanoscale ◽  
2021 ◽  
Author(s):  
Matias Luis Picchio ◽  
Julian Bergueiro Álvarez ◽  
Stefanie Wedepohl ◽  
Roque J Minari ◽  
Cecilia Ines Alvarez Igarzabal ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Contrast Agent ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Cyanine Dye ◽  
Hydrophobic Protein ◽  
Nir Dyes ◽  
Protein Pockets ◽  
J Aggregates ◽  
Innovative Concept

After several decades of development in the field of near-infrared (NIR) dyes for photothermal therapy (PTT), indocyanine green (ICG) still remains the only FDA-approved NIR contrast agent. However, upon NIR...

scholarly journals Recent advances in applications of multimodal ultrasound-guided photoacoustic imaging technology

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Shanshan Wang ◽  
Yunfeng Zhao ◽  
Ye Xu
Keyword(s):  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Imaging Techniques ◽  
Color Doppler ◽  
Power Doppler ◽  
Infrared Region ◽  
Detection Methods ◽  
Imaging Mode ◽  
Nonlinear Imaging ◽  
The Relationship

Abstract Photoacoustic imaging (PAI) is often performed simultaneously with ultrasound imaging and can provide functional and cellular information regarding the tissues in the anatomical markers of the imaging. This paper describes in detail the basic principles of photoacoustic/ultrasound (PA/US) imaging and its application in recent years. It includes near-infrared-region PA, photothermal, photodynamic, and multimode imaging techniques. Particular attention is given to the relationship between PAI and ultrasonic imaging; the latest high-frequency PA/US imaging of small animals, which involves not only B-mode, but also color Doppler mode, power Doppler mode, and nonlinear imaging mode; the ultrasonic model combined with PAI, including the formation of multimodal imaging; the preclinical imaging methods; and the most effective detection methods for clinical research for the future.

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