scholarly journals Novel amperometric glucose biosensor based on MXene nanocomposite

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
R. B. Rakhi ◽  
Pranati Nayak ◽  
Chuan Xia ◽  
Husam N. Alshareef
Keyword(s):  
Au Nanoparticles ◽  
Synergistic Effects ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Carbon Electrode ◽  
Potential Candidate ◽  
Amperometric Response ◽  
Excellent Stability ◽  
Electrochemical Transducer

Abstract A biosensor platform based on Au/MXene nanocomposite for sensitive enzymatic glucose detection is reported. The biosensor leverages the unique electrocatalytic properties and synergistic effects between Au nanoparticles and MXene sheets. An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). The biomediated Au nanoparticles play a significant role in facilitating the electron exchange between the electroactive center of GOx and the electrode. The GOx/Au/MXene/Nafion/GCE biosensor electrode displayed a linear amperometric response in the glucose concentration range from 0.1 to 18 mM with a relatively high sensitivity of 4.2 μAmM−1 cm−2 and a detection limit of 5.9 μM (S/N = 3). Furthermore, the biosensor exhibited excellent stability, reproducibility and repeatability. Therefore, the Au/MXene nanocomposite reported in this work is a potential candidate as an electrochemical transducer in electrochemical biosensors.

Glucose Biosensor Based on Glucose Oxidase-Horseradish Peroxidase/Multiporous Tin Oxide (SnO2) Modified Electrode

2021 ◽  
Vol 21 (5) ◽  
pp. 3059-3064
Author(s):  
A. K. M. Kafi ◽  
Aizam Bin Kasri ◽  
Rajan Jose
Keyword(s):  
Horseradish Peroxidase ◽  
Glucose Oxidase ◽  
Tin Oxide ◽  
Electrode Potential ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Lower Detection Limit ◽  
Vis Spectroscopy ◽  
Lower Detection

The fabrication of a network of glucose oxidase-horseradish peroxidase/tin oxide (GOx-HRP/SnO2), immobilized onto a glassy carbon electrode (GCE) and its utilization as a biosensor for glucose detection is reported. The network established with GOx-HRP/SnO2 possess high sensitivity and stability by performing the electrocatalytic features in the sensing of glucose. The turbidity of fabrication had been scanned and analyzed using UV-vis spectroscopy. The morphology and composition of the fabricated GOx-HRP/SnO2 networks were characterized by scanning electron microscopy (SEM). Cyclic voltammetry and amperometry were employed to study the electrochemical properties of the proposed biosensor. The effect of applied electrode potential and pH were systemically investigated. The biosensor responds to glucose at work potential values between −400 mV, and exhibited a lower detection limit (0.025 mM) and long linear range (0.25 to 7.0 mM), and was resistant to common interferences.

Nanoporous copper oxide ribbon assembly of free-standing nanoneedles as biosensors for glucose

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5205-5215 ◽  
Author(s):  
Shaodong Sun ◽  
Yuexia Sun ◽  
Anran Chen ◽  
Xiaozhe Zhang ◽  
Zhimao Yang
Keyword(s):  
Detection Limit ◽  
High Sensitivity ◽  
Solution Phase ◽  
Glucose Detection ◽  
Two Dimensional ◽  
Free Standing ◽  
Amperometric Response ◽  
Nanoporous Copper ◽  
Green Solution ◽  
Promising Electrode Material

Two-dimensional (2D) hierarchical nanoporous CuO ribbons were successfully synthesized by a green solution-phase route. They serve as a promising electrode material for nonenzymatic glucose detection and show high sensitivity, a low detection limit, fast amperometric response and good selectivity.

scholarly journals Electrospun porous La-Sr-Co-Ni-O nanofibers for highly sensitive non-enzymatic glucose detection

2022 ◽  
Author(s):  
Kasci D Pelucarte ◽  
Tashi A Hatchell ◽  
Gibin George ◽  
Sivasankara Rao Ede ◽  
Menuka Adhikari ◽  
...  
Keyword(s):  
Metal Oxides ◽  
Perovskite Structure ◽  
High Sensitivity ◽  
Environmental Applications ◽  
Glucose Detection ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Excellent Stability

Glucose biosensors are widely used for clinical, industrial, and environmental applications. Nonenzymatic electrochemical glucose biosensors based on metal oxides with a perovskite structure have exhibited high sensitivity, excellent stability, and...

A Novel and Simple Electrochemical Glucose Biosensor Based on a Silicon Nanowire Array Electrode

2014 ◽  
Author(s):  
Che-Wei Hsu ◽  
Wen-Chao Feng ◽  
Kang J. Chang ◽  
Gou-Jen Wang
Keyword(s):  
Low Cost ◽  
Silicon Nanowire ◽  
Nanowire Array ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Redox Peak ◽  
Array Electrode ◽  
Silicon Nanowire Array ◽  
Very High

In this study, a novel and simple electrochemical glucose biosensor based on a silicon nanowire array (SNA) electrode was proposed. Metal-assisted etching (MAE) method using an AgNO3 and HF mixing solution as the etchant was employed to grow the silicon nanowire array (SNA) electrode. A thin gold shell is then sputtered over each silicon nanowire. Potassium ferricyanide, glucose oxidase (GOx), and a Nafion thin film were then sequentially coated onto the fabricated SNA for glucose detection. The processing time of the MAE and sputtering as well as the GOx concentration were optimized in terms of the redox peak currents of the SNA electrode. Compared with the corresponding plane gold electrode, the effective sensing area of the synthesized SNA electrode was measured to be 6.12 folds. Actual glucose detections demonstrated that the proposed SNA array electrode could operate in a linear range of 0.55 mM-11.02 mM and a very high sensitivity of 346 μA mM−1 cm−2. The proposed SNA electrode based glucose biosensor possesses advantages of simple fabrication process, low cost, and high sensitivity. It is feasible for future clinical applications.

scholarly journals Enhancement of amperometric response of glucose biosensor by electrodeposition of silver nanoparticles onto chitosan-modified electrode

2017 ◽  
Author(s):  
Hossein Zare ◽  
Ghasem Najafpour ◽  
Mohsen Jahanshahi ◽  
Mostafa Rahimnejad ◽  
Mohsen Rezvani
Keyword(s):  
Silver Nanoparticles ◽  
Modified Electrode ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Single Pulse ◽  
Glucose Biosensor ◽  
Amperometric Response ◽  
Highly Sensitive ◽  
Menten Constant ◽  
Electrodeposition Of Silver

A highly sensitive biosensor based on silver nanoparticles (AgNPs) was fabricated for glucose detection in aqueous phase. Firstly, a platinum (Pt) electrode was modified with the mixture of glucose oxidase and chitosan. AgNPs were electrodeposited into the modified electrode by single pulse potentiostatic method at –0.4 V. The electrochemical performance of the modified electrode was evaluated by cyclic voltammetry and amperometry. The fabricated biosensor had a high sensitivity of 58.6 μA mM−1 cm−2 and detection limit of 4.4 μM glucose at a signal to noise ratio of 3. In addition, the biosensor showed a short response time less than 5 s and a wide linear range of 0.05-11.5 mM. The apparent Michaelis–Menten constant (KM) was found to be 9.14 mM. In addition, thermal stability and anti-interference ability of the biosensor were investigated. The results demonstrated that AgNPs enhanced the analytical performance of the biosensor.

Rapid sub-micromolar amperometric enzyme biosensing with free substrate access but without nanomaterial signalling support: oxidase-based glucose detection as a proof-of-principle example

2020 ◽  
Vol 56 (52) ◽  
pp. 7132-7135
Author(s):  
Kittiya Sakdaphetsiri ◽  
Thana Thaweeskulchai ◽  
Albert Schulte
Keyword(s):  
Glucose Oxidase ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Gelatin Films ◽  
Pt Electrodes ◽  
Vapor Treatment ◽  
Proof Of Principle

Reported is a high-sensitivity glucose biosensor with a simple since nanomaterial-free layout of the signalling platform. Drop-dried glucose oxidase was covalently fixed to drop-dried gelatin films on Pt-electrodes, by glutaraldehyde vapor treatment.

Low Potential Stable Glucose Detection at Carbon Nanotube Modified Gold Electrodes

2003 ◽  
Vol 788 ◽  
Author(s):  
S. G. Wang ◽  
Qing Zhang ◽  
Ruili Wang ◽  
D. J. Yang ◽  
S. F. Yoon ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Electron Transfer ◽  
Carbon Nanotube ◽  
Glucose Biosensor ◽  
Electrochemical Reactions ◽  
Gold Electrodes ◽  
Glucose Detection ◽  
Amperometric Response ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes

ABSTRACTThe subtle electronic properties and large electroactive surface of carbon nanotubes (CNTs) suggest that they have the ability to promote electron-transfer and favor electrocatalytic behavior in electrochemical reactions when they are employed as an electrode. In this paper, CNT-modified gold electrodes for glucose biosensor have been fabricated using multi-walled carbon nanotubes. The CNT-based electrode exhibits a strong and stable amperometric response toward glucose even at a low potential of +0.35 V versus Ag/AgCl in comparison with the glassy carbon-based electrode.

scholarly journals Flexible Metal/Polymer Composite Films Embedded with Silver Nanowires as a Stretchable and Conductive Strain Sensor for Human Motion Monitoring

Micromachines ◽  
2019 ◽  
Vol 10 (6) ◽  
pp. 372 ◽  
Author(s):  
Jinjin Luan ◽  
Qing Wang ◽  
Xu Zheng ◽  
Yao Li ◽  
Ning Wang
Keyword(s):  
Polymer Composite ◽  
Silver Nanowires ◽  
Composite Films ◽  
Strain Sensor ◽  
High Sensitivity ◽  
Human Motion ◽  
Applied Strain ◽  
Potential Candidate ◽  
Flexible Metal ◽  
Metal Polymer

To avoid conductive failure due to the cracks of the metal thin film under external loads for the wearable strain sensor, a stretchable metal/polymer composite film embedded with silver nanowires (AgNWs) was examined as a potential candidate. The combination of Ag film and AgNWs enabled the fabrication of a conductive film that was applied as a high sensitivity strain sensor, with gauge factors of 7.1 under the applied strain of 0–10% and 21.1 under the applied strain of 10–30%. Furthermore, the strain sensor was demonstrated to be highly reversible and remained stable after 1000 bending cycles. These results indicated that the AgNWs could act as elastic conductive bridges across cracks in the metal film to maintain high conductivity under tensile and bending loads. As such, the strain sensor engineered herein was successfully applied in the real-time detection and monitoring of large motions of joints and subtle motions of the mouth.

Temperature-induced amperometric glucose biosensor based on a poly(N-vinylcaprolactam)/graphene oxide composite film

The Analyst ◽  
2019 ◽  
Vol 144 (6) ◽  
pp. 1960-1967 ◽  
Author(s):  
Chao Chen ◽  
Pengcheng Zhao ◽  
Meijun Ni ◽  
Chunyan Li ◽  
Yixi Xie ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Composite Film ◽  
Glucose Oxidase ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Glucose Biosensor ◽  
Carbon Electrode ◽  
Oxide Composite

A temperature-induced sensing film consisting of poly(N-vinylcaprolactam) (PVCL), graphene oxide (GO) and glucose oxidase (GOD) was fabricated and used to modify a glassy carbon electrode (GCE).

Synergistic effects of SnO2 and Au nanoparticles decorated on WS2 nanosheets for flexible, room-temperature CO gas sensing

2021 ◽  
Vol 332 ◽  
pp. 129493
Author(s):  
Jae-Hun Kim ◽  
Jin-Young Kim ◽  
Ali Mirzaei ◽  
Hyoun Woo Kim ◽  
Sang Sub Kim
Keyword(s):  
Room Temperature ◽  
Au Nanoparticles ◽  
Gas Sensing ◽  
Synergistic Effects ◽  
Ws2 Nanosheets ◽  
Co Gas
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