scholarly journals Electrospun porous La-Sr-Co-Ni-O nanofibers for highly sensitive non-enzymatic glucose detection

2022 ◽  
Author(s):  
Kasci D Pelucarte ◽  
Tashi A Hatchell ◽  
Gibin George ◽  
Sivasankara Rao Ede ◽  
Menuka Adhikari ◽  
...  
Keyword(s):  
Metal Oxides ◽  
Perovskite Structure ◽  
High Sensitivity ◽  
Environmental Applications ◽  
Glucose Detection ◽  
Glucose Biosensors ◽  
Highly Sensitive ◽  
Excellent Stability

Glucose biosensors are widely used for clinical, industrial, and environmental applications. Nonenzymatic electrochemical glucose biosensors based on metal oxides with a perovskite structure have exhibited high sensitivity, excellent stability, and...

scholarly journals Novel amperometric glucose biosensor based on MXene nanocomposite

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
R. B. Rakhi ◽  
Pranati Nayak ◽  
Chuan Xia ◽  
Husam N. Alshareef
Keyword(s):  
Au Nanoparticles ◽  
Synergistic Effects ◽  
High Sensitivity ◽  
Glucose Biosensor ◽  
Glucose Detection ◽  
Carbon Electrode ◽  
Potential Candidate ◽  
Amperometric Response ◽  
Excellent Stability ◽  
Electrochemical Transducer

Abstract A biosensor platform based on Au/MXene nanocomposite for sensitive enzymatic glucose detection is reported. The biosensor leverages the unique electrocatalytic properties and synergistic effects between Au nanoparticles and MXene sheets. An amperometric glucose biosensor is fabricated by the immobilization of glucose oxidase (GOx) enzyme on Nafion solubilized Au/ MXene nanocomposite over glassy carbon electrode (GCE). The biomediated Au nanoparticles play a significant role in facilitating the electron exchange between the electroactive center of GOx and the electrode. The GOx/Au/MXene/Nafion/GCE biosensor electrode displayed a linear amperometric response in the glucose concentration range from 0.1 to 18 mM with a relatively high sensitivity of 4.2 μAmM−1 cm−2 and a detection limit of 5.9 μM (S/N = 3). Furthermore, the biosensor exhibited excellent stability, reproducibility and repeatability. Therefore, the Au/MXene nanocomposite reported in this work is a potential candidate as an electrochemical transducer in electrochemical biosensors.

Low-cost and high sensitivity glucose sandwich detection using a plasmonic nanodisk metasurface

Nanoscale ◽  
2020 ◽  
Vol 12 (19) ◽  
pp. 10809-10815 ◽  
Author(s):  
Zhongwen Long ◽  
Yuzhang Liang ◽  
Lei Feng ◽  
Hui Zhang ◽  
Mingze Liu ◽  
...  
Keyword(s):  
Large Scale ◽  
Low Cost ◽  
High Sensitivity ◽  
Glucose Detection ◽  
Sensing Platform ◽  
Highly Sensitive

A low-cost, large scale plasmonic metasurface sensing platform shows enormous potential for highly sensitive and selective SERS-based glucose detection.

scholarly journals Enzyme immobilisation on poly-l-lysine-containing calcium phosphate particles for highly sensitive glucose detection

RSC Advances ◽  
2019 ◽  
Vol 9 (19) ◽  
pp. 10832-10841 ◽  
Author(s):  
Suzuka Kojima ◽  
Fukue Nagata ◽  
Masahiko Inagaki ◽  
Shinichi Kugimiya ◽  
Katsuya Kato
Keyword(s):  
Calcium Phosphate ◽  
Glucose Sensor ◽  
Enzyme Stability ◽  
High Sensitivity ◽  
Glucose Detection ◽  
Enzyme Immobilisation ◽  
Highly Sensitive ◽  
High Enzyme ◽  
Calcium Phosphate Particles

The as-synthesised poly-l-lysine-containing HAp with high enzyme stability could be a candidate for a glucose sensor with high sensitivity.

scholarly journals Constructing a TiO2/PDA core/shell nanorod array electrode as a highly sensitive and stable photoelectrochemical glucose biosensor

RSC Advances ◽  
2020 ◽  
Vol 10 (17) ◽  
pp. 10017-10022 ◽  
Author(s):  
Wei Xu ◽  
Wenke Yang ◽  
Hongkai Guo ◽  
Lianyuan Ge ◽  
Jinchun Tu ◽  
...  
Keyword(s):  
Detection Limit ◽  
High Sensitivity ◽  
Nanorod Array ◽  
Glucose Biosensor ◽  
Core Shell ◽  
Glucose Biosensors ◽  
Low Detection Limit ◽  
Array Electrode ◽  
Highly Sensitive

Developing stable PEC glucose biosensors with high sensitivity and low detection limit is highly desirable in the biosensor field.

Cu nanoparticle decorated sulfur-based polymers for highly sensitive nonenzymatic glucose detection

2021 ◽  
Author(s):  
yuan liao ◽  
min liu ◽  
jie liu ◽  
Ji-Hua Zhu ◽  
Jingjiang Liu ◽  
...  
Keyword(s):  
High Sensitivity ◽  
Glucose Detection ◽  
Copper Nanoparticle ◽  
Highly Sensitive ◽  
Sensitivity And Selectivity ◽  
Cu Nanoparticle

A novel copper nanoparticle decorated sulfur-based polymers, Cu@S-co-BIM, was designed and constructed for chronoamperometry analysis of glucose with the high sensitivity and selectivity. S-co-BIM was synthesized by inverse vulcanization means...

High-sensitivity detection of gold labels by high-angle dark-field STEM imaging

1990 ◽  
Vol 48 (3) ◽  
pp. 892-893 ◽  
Author(s):  
Max T. Otten
Keyword(s):  
High Sensitivity ◽  
Dark Field ◽  
Bright Field ◽  
Backscattered Electron Imaging ◽  
Backscattered Electrons ◽  
Average Atomic Number ◽  
Highly Sensitive ◽  
Backscattered Electron ◽  
Electron Imaging ◽  
High Sensitivity Detection

Labelling of antibodies with small gold probes is a highly sensitive technique for detecting specific molecules in biological tissue. Larger gold probes are usually well visible in TEM or STEM Bright-Field images of unstained specimens. In stained specimens, however, the contrast of the stain is frequently the same as that of the gold labels, making it virtually impossible to identify the labels, especially when smaller gold labels are used to increase the sensitivity of the immunolabelling technique. TEM or STEM Dark-Field images fare no better (Figs. 1a and 2a), again because of the absence of a clear contrast difference between gold labels and stain.Potentially much more useful is backscattered-electron imaging, since this will show differences in average atomic number which are sufficiently large between the metallic gold and the stains normally used. However, for the thin specimens and at high accelerating voltages of the STEM, the yield of backscattered electrons is very small, resulting in a very weak signal. Consequently, the backscattered-electron signal is often too noisy for detecting small labels, even for large spot sizes.

scholarly journals Role of MRI evaluation in acute secondary inability to walk in children

2021 ◽  
Vol 52 (1) ◽  
Author(s):  
K. H. Sedeek ◽  
K. Aboualfotouh ◽  
S. M. Hassanein ◽  
N. M. Osman ◽  
M. H. Shalaby
Keyword(s):  
Transverse Myelitis ◽  
High Sensitivity ◽  
Acute Disseminated Encephalomyelitis ◽  
Limb Weakness ◽  
Non Invasive ◽  
Highly Sensitive ◽  
Common Causes ◽  
Bilateral Lower Limb ◽  
Severity Of The Disease

Abstract Background Acute bilateral lower limb weakness is a common problem in children which necessitates a rapid method for diagnosis. MRI is a non-invasive imaging technique that produces high-quality images of the internal structure of the brain and spinal cord. Results MRI was very helpful in reaching rapid and prompt diagnosis in children with acute inability to walk. Acute disseminated encephalomyelitis (ADEM), Guillain–Barré syndrome (GBS), and acute transverse myelitis (ATM) were the most common causes in our study. MRI proved to be of high sensitivity in detecting the lesions and reaching the diagnosis in ADEM and GBS; however, there was no significant relation between the lesions’ size, enhancement pattern, and severity of the disease or prognosis, yet in ATM the site of the lesion and number of cord segment affection were significantly related to the severity of the disease and prognosis. Conclusion MRI is a quick tool to reach the diagnosis of children with acute secondary inability to walk, and to eliminate other differential diagnosis which is essential for proper treatment and rapid full recovery. It is highly sensitive in detecting the lesions, their site and size.

scholarly journals Highly sensitive detection of nitrobenzene by a series of fluorescent 2D zinc(ii) metal–organic frameworks with a flexible triangular ligand

RSC Advances ◽  
2021 ◽  
Vol 11 (39) ◽  
pp. 23975-23984
Author(s):  
Xue Yang ◽  
Yixia Ren ◽  
Hongmei Chai ◽  
Xiufang Hou ◽  
Zhixiang Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Metal Organic Frameworks ◽  
High Sensitivity ◽  
Fluorescent Sensors ◽  
Sensitive Detection ◽  
Donor Ligands ◽  
Highly Sensitive ◽  
Metal Organic ◽  
Highly Sensitive Detection

Four fluorescent 2D Zn-MOFs based on a flexible triangular ligand and linear N-donor ligands are hydrothermally prepared and used to detect nitrobenzene in aqueous solution with high sensitivity, demonstrating their potential as fluorescent sensors.

Rapid, highly sensitive and quantitative detection of interleukin 6 based on SERS magnetic immunoassay

2021 ◽  
Vol 13 (15) ◽  
pp. 1823-1831
Author(s):  
Xiaomei Wang ◽  
Li Ma ◽  
Shijiao Sun ◽  
Tingwei Liu ◽  
Hao Zhou ◽  
...  
Keyword(s):  
Interleukin 6 ◽  
High Sensitivity ◽  
Quantitative Detection ◽  
Detection Time ◽  
Highly Sensitive ◽  
Sandwich Method

We have developed a SERS magnetic immunoassay method based on the principle of sandwich method for rapid and quantitative detection of IL-6. The developed SERS method has the advantages of high sensitivity and detection time is only 15 min.

scholarly journals Highly Sensitive Fluorescent Detection of Acetylcholine Based on the Enhanced Peroxidase-Like Activity of Histidine Coated Magnetic Nanoparticles

Nanomaterials ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 1207
Author(s):  
Hong Jae Cheon ◽  
Quynh Huong Nguyen ◽  
Moon Il Kim
Keyword(s):  
Magnetic Nanoparticles ◽  
High Sensitivity ◽  
High Specificity ◽  
Choline Oxidase ◽  
Fluorescent Detection ◽  
One Pot ◽  
Site Structure ◽  
Specificity And Sensitivity ◽  
Highly Sensitive ◽  
Peroxidase Mimics

Inspired by the active site structure of natural horseradish peroxidase having iron as a pivotal element with coordinated histidine residues, we have developed histidine coated magnetic nanoparticles (His@MNPs) with relatively uniform and small sizes (less than 10 nm) through one-pot heat treatment. In comparison to pristine MNPs and other amino acid coated MNPs, His@MNPs exhibited a considerably enhanced peroxidase-imitating activity, approaching 10-fold higher in catalytic reactions. With the high activity, His@MNPs then were exploited to detect the important neurotransmitter acetylcholine. By coupling choline oxidase and acetylcholine esterase with His@MNPs as peroxidase mimics, target choline and acetylcholine were successfully detected via fluorescent mode with high specificity and sensitivity with the limits of detection down to 200 and 100 nM, respectively. The diagnostic capability of the method is demonstrated by analyzing acetylcholine in human blood serum. This study thus demonstrates the potential of utilizing His@MNPs as peroxidase-mimicking nanozymes for detecting important biological and clinical targets with high sensitivity and reliability.

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