Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process

2010 ◽  
Vol 132 (31) ◽  
pp. 10645-10647 ◽  
Author(s):  
Qiuning Lin ◽  
Qi Huang ◽  
Chunyan Li ◽  
Chunyan Bao ◽  
Zhenzhen Liu ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Anticancer Drug ◽  
Two Photon ◽  
Photon Process

Coumarin-containing photo-responsive nanocomposites for NIR light-triggered controlled drug release via a two-photon process

2013 ◽  
Vol 1 (43) ◽  
pp. 5942 ◽  
Author(s):  
Weidong Ji ◽  
Najun Li ◽  
Dongyun Chen ◽  
Xiuxiu Qi ◽  
Wenwei Sha ◽  
...  
Keyword(s):  
Drug Release ◽  
Controlled Drug Release ◽  
Two Photon ◽  
Nir Light ◽  
Photon Process

Disulfide-gated mesoporous silica nanoparticles designed for two-photon-triggered drug release and imaging

2015 ◽  
Vol 3 (31) ◽  
pp. 6456-6461 ◽  
Author(s):  
Jonas G. Croissant ◽  
Christian Qi ◽  
Olivier Mongin ◽  
Vincent Hugues ◽  
Mireille Blanchard-Desce ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Cancer Cell ◽  
Mesoporous Silica Nanoparticles ◽  
Cell Killing ◽  
Two Photon ◽  
Triggered Drug Release

We report two-photon cancer cell killing through mesoporous silica nanogates.

Two-photon sensitized hollow Gd2O3:Eu3+nanocomposites for real-time dual-mode imaging and monitoring of anticancer drug release

2016 ◽  
Vol 52 (7) ◽  
pp. 1447-1450 ◽  
Author(s):  
Tingting Shen ◽  
Yu Zhang ◽  
Alexander M. Kirillov ◽  
Huijuan Cai ◽  
Kun Huang ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Dual Mode ◽  
Two Photon

scholarly journals Autonomous in Vitro Anticancer Drug Release from Mesoporous Silica Nanoparticles by pH-Sensitive Nanovalves

2010 ◽  
Vol 132 (36) ◽  
pp. 12690-12697 ◽  
Author(s):  
Huan Meng ◽  
Min Xue ◽  
Tian Xia ◽  
Yan-Li Zhao ◽  
Fuyuhiko Tamanoi ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Anticancer Drug ◽  
Mesoporous Silica Nanoparticles ◽  
Ph Sensitive

Mesoporous Silica Molecular Sieve based Nanocarriers: Transpiring Drug Dissolution Research

2017 ◽  
Vol 23 (3) ◽  
pp. 467-480 ◽  
Author(s):  
Satyanarayan Pattnaik ◽  
Kamla Pathak
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Molecular Sieves ◽  
Release Kinetics ◽  
Drug Loading ◽  
Scale Up ◽  
Water Soluble ◽  
Drug Dissolution ◽  
Water Soluble Drugs ◽  
Loading Methods

Background: Improvement of oral bioavailability through enhancement of dissolution for poorly soluble drugs has been a very promising approach. Recently, mesoporous silica based molecular sieves have demonstrated excellent properties to enhance the dissolution velocity of poorly water-soluble drugs. Description: Current research in this area is focused on investigating the factors influencing the drug release from these carriers, the kinetics of drug release and manufacturing approaches to scale-up production for commercial manufacture. Conclusion: This comprehensive review provides an overview of different methods adopted for synthesis of mesoporous materials, influence of processing factors on properties of these materials and drug loading methods. The drug release kinetics from mesoporous silica systems, the manufacturability and stability of these formulations are reviewed. Finally, the safety and biocompatibility issues related to these silica based materials are discussed.

Facile synthesis of organosilica-capped mesoporous silica nanocarriers with selective redox-triggered drug release properties for safe tumor chemotherapy

2019 ◽  
Vol 7 (5) ◽  
pp. 1825-1832 ◽  
Author(s):  
Luying Shen ◽  
Shan Pan ◽  
Dechao Niu ◽  
Jianping He ◽  
Xiaobo Jia ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Facile Synthesis ◽  
Triggered Drug Release ◽  
Facile Route

We develop a facile route to synthesize organosilica-capped mesoporous silica nanocarriers for efficient and safe redox-triggered tumor chemotherapy.

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