Two-photon sensitized hollow Gd2O3:Eu3+nanocomposites for real-time dual-mode imaging and monitoring of anticancer drug release

2016 ◽  
Vol 52 (7) ◽  
pp. 1447-1450 ◽  
Author(s):  
Tingting Shen ◽  
Yu Zhang ◽  
Alexander M. Kirillov ◽  
Huijuan Cai ◽  
Kun Huang ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Dual Mode ◽  
Two Photon

scholarly journals NIR-Responsive Lysosomotropic Phototrigger: ʽAIE + ESIPTʼ Active Naphthalene Based Single Component Photoresponsive Nanocarrier with Two-Photon Uncaging and Real-Time Monitoring Ability

2021 ◽  
Author(s):  
Biswajit Roy ◽  
Rakesh Mengji ◽  
Samrat Roy ◽  
Bipul Pal ◽  
Avijit Jana ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Real Time ◽  
Near Infrared ◽  
Single Component ◽  
Photon Absorption ◽  
Real Time Monitoring ◽  
Two Photon ◽  
Nir Light

In recent times, organelle-targeted drug delivery systems gained tremendous attention due to the site specific delivery of active drug molecules resulting in enhanced bioefficacy. In this context, the phototriggered drug delivery system (DDS) for releasing an active molecule is superior as it provides spatial and temporal control over the release. So far, near infrared (NIR) light responsive organelle targeted DDS has not yet been developed. Hence, we introduced a two-photon NIR-light responsive lysosome targeted ʽAIE + ESIPTʼ active single component DDS based on naphthalene chromophore. The Two-photon absorption cross-section of our DDS is 142 GM at 850 nm. The DDS was converted into pure organic nanoparticles for biological applications. Our nano-DDS is capable of selective targeting, AIE-luminogenic imaging, and drug release within the lysosome. In vitro studies using cancerous cell lines showed that our single component photoresponsive nanocarrier exhibited enhanced cytotoxicity and real-time monitoring ability of the drug release.

scholarly journals Real-Time Monitoring of Anticancer Drug Release with Highly Fluorescent Star-Conjugated Copolymer as a Drug Carrier

2014 ◽  
Vol 15 (4) ◽  
pp. 1355-1364 ◽  
Author(s):  
Feng Qiu ◽  
Dali Wang ◽  
Qi Zhu ◽  
Lijuan Zhu ◽  
Gangsheng Tong ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Drug Carrier ◽  
Real Time Monitoring ◽  
Conjugated Copolymer

Real-time monitoring of anticancer drug release in vitro and in vivo on titania nanoparticles triggered by external glutathione

Talanta ◽  
2012 ◽  
Vol 88 ◽  
pp. 631-637 ◽  
Author(s):  
Mira Kim ◽  
Ji Hye Seo ◽  
Won Il Jeon ◽  
Mi-Yeon Kim ◽  
Keunchang Cho ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Titania Nanoparticles ◽  
Real Time Monitoring ◽  
Release In Vitro

Real-Time In Vivo Quantitative Monitoring of Drug Release by Dual-Mode Magnetic Resonance and Upconverted Luminescence Imaging

2014 ◽  
Vol 53 (18) ◽  
pp. 4551-4555 ◽  
Author(s):  
Jianan Liu ◽  
Jiwen Bu ◽  
Wenbo Bu ◽  
Shengjian Zhang ◽  
Limin Pan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Drug Release ◽  
Real Time ◽  
Dual Mode ◽  
Luminescence Imaging ◽  
Quantitative Monitoring

Anticancer Drug Release from a Mesoporous Silica Based Nanophotocage Regulated by Either a One- or Two-Photon Process

2010 ◽  
Vol 132 (31) ◽  
pp. 10645-10647 ◽  
Author(s):  
Qiuning Lin ◽  
Qi Huang ◽  
Chunyan Li ◽  
Chunyan Bao ◽  
Zhenzhen Liu ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Anticancer Drug ◽  
Two Photon ◽  
Photon Process

Redox/ATP switchable theranostic nanoparticles for real-time fluorescence monitoring of doxorubicin delivery

2018 ◽  
Vol 6 (14) ◽  
pp. 2089-2103 ◽  
Author(s):  
Yi Lin ◽  
Yidi Yang ◽  
Jianqin Yan ◽  
Jun Chen ◽  
Jun Cao ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Real Time Monitoring ◽  
The Real ◽  
Theranostic Nanoparticles ◽  
Doxorubicin Delivery

Redox/ATP switchable theranostic nanoparticles (TNs) with precise specificity and controllable mobility were developed for the real-time monitoring of anticancer drug release.

Real-Time In Vivo Quantitative Monitoring of Drug Release by Dual-Mode Magnetic Resonance and Upconverted Luminescence Imaging

2014 ◽  
Vol 126 (18) ◽  
pp. 4639-4643 ◽  
Author(s):  
Jianan Liu ◽  
Jiwen Bu ◽  
Wenbo Bu ◽  
Shengjian Zhang ◽  
Limin Pan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Drug Release ◽  
Real Time ◽  
Dual Mode ◽  
Luminescence Imaging ◽  
Quantitative Monitoring

Perylene-Derived Single-Component Organic Nanoparticles with Tunable Emission: Efficient Anticancer Drug Carriers with Real-Time Monitoring of Drug Release

ACS Nano ◽  
2014 ◽  
Vol 8 (6) ◽  
pp. 5939-5952 ◽  
Author(s):  
Avijit Jana ◽  
Kim Truc Nguyen ◽  
Xin Li ◽  
Pengcheng Zhu ◽  
Nguan Soon Tan ◽  
...  
Keyword(s):  
Drug Release ◽  
Real Time ◽  
Anticancer Drug ◽  
Drug Carriers ◽  
Single Component ◽  
Real Time Monitoring ◽  
Organic Nanoparticles ◽  
Tunable Emission
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