pH/NIR-Responsive Polypyrrole-Functionalized Fibrous Localized Drug-Delivery Platform for Synergistic Cancer Therapy

2018 ◽  
Vol 10 (24) ◽  
pp. 20256-20270 ◽  
Author(s):  
Arjun Prasad Tiwari ◽  
Tae In Hwang ◽  
Jung-Mi Oh ◽  
Bikendra Maharjan ◽  
Sungkun Chun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Delivery Platform ◽  
Localized Drug Delivery

scholarly journals Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy

2018 ◽  
Vol 9 ◽  
Author(s):  
Sangram Raut ◽  
Linda Mooberry ◽  
Nirupama Sabnis ◽  
Ashwini Garud ◽  
Akpedje Serena Dossou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Biological Barriers ◽  
Delivery Platform

Precise delivery of a multifunctional nanosystem for MRI-guided cancer therapy and monitoring of tumor response by functional diffusion-weighted MRI

2019 ◽  
Vol 7 (18) ◽  
pp. 2926-2937 ◽  
Author(s):  
Zeyu Xiao ◽  
Leung Chan ◽  
Dong Zhang ◽  
Cuiqing Huang ◽  
Chaoming Mei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Mr Imaging ◽  
High Efficiency ◽  
Tumor Response ◽  
Diffusion Weighted Mri ◽  
Diffusion Weighted ◽  
Delivery Platform ◽  
Mri Guided ◽  
Cancer Theranostics

Herein we synthesize a cRGD peptide-conjugated PLGA nanosystem which is a high-efficiency drug-delivery platform for MR imaging-guided cancer theranostics.

Redox-Responsive Polyphosphate Nanosized Assemblies: A Smart Drug Delivery Platform for Cancer Therapy

2011 ◽  
Vol 12 (6) ◽  
pp. 2407-2415 ◽  
Author(s):  
Jinyao Liu ◽  
Yan Pang ◽  
Wei Huang ◽  
Zhaoyang Zhu ◽  
Xinyuan Zhu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Redox Responsive ◽  
Delivery Platform ◽  
Smart Drug ◽  
Smart Drug Delivery

Charge reversal induced colloidal hydrogel acts as a multi-stimuli responsive drug delivery platform for synergistic cancer therapy

2019 ◽  
Vol 6 (4) ◽  
pp. 711-716 ◽  
Author(s):  
Gang He ◽  
Sheng Chen ◽  
Yunjun Xu ◽  
Zhaohua Miao ◽  
Yan Ma ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Stimuli Responsive ◽  
Gelatin Nanoparticles ◽  
Charge Reversal ◽  
Delivery Platform ◽  
A Charge

A charge reversal induced colloidal hydrogel composed of amphoteric gelatin nanoparticles (Gela NPs) and melanin-like polydopamine nanoparticles (PDA NPs) was developed for synergistic cancer therapy.

Glutathione-responsive nanoscale MOFs for effective intracellular delivery of the anticancer drug 6-mercaptopurine

2020 ◽  
Vol 56 (47) ◽  
pp. 6448-6451 ◽  
Author(s):  
Ming Gong ◽  
Jian Yang ◽  
Yongsheng Li ◽  
Jinlou Gu
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drug ◽  
Disulfide Bonds ◽  
Intracellular Delivery ◽  
Delivery Platform

A glutathione-responsive drug-delivery platform based on nanoMOFs was developed for selective cancer therapy through the introduction of disulfide bonds.

Synthesis, characterization, and formulation of poly-puerarin as a biodegradable and biosafe drug delivery platform for anti-cancer therapy

2019 ◽  
Vol 7 (5) ◽  
pp. 2152-2164 ◽  
Author(s):  
Tianqi Yi ◽  
Jun Huang ◽  
Xuewen Chen ◽  
Haiyun Xiong ◽  
Yang Kang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Tumour Therapy ◽  
Anti Cancer ◽  
Delivery Platform

Poly-puerarin, a novel biodegradable biomaterial as a drug delivery platform in anti-tumour therapy.

scholarly journals Systemic and Local Silk-Based Drug Delivery Systems for Cancer Therapy

Cancers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 5389
Author(s):  
Anna Florczak ◽  
Tomasz Deptuch ◽  
Kamil Kucharczyk ◽  
Hanna Dams-Kozlowska
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Kinase Inhibitors ◽  
Drug Carrier ◽  
Inorganic Nanoparticles ◽  
Entire Body ◽  
Delivery Platform ◽  
Particle Preparation ◽  
Systemic Drug Delivery

For years, surgery, radiotherapy, and chemotherapy have been the gold standards to treat cancer, although continuing research has sought a more effective approach. While advances can be seen in the development of anticancer drugs, the tools that can improve their delivery remain a challenge. As anticancer drugs can affect the entire body, the control of their distribution is desirable to prevent systemic toxicity. The application of a suitable drug delivery platform may resolve this problem. Among other materials, silks offer many advantageous properties, including biodegradability, biocompatibility, and the possibility of obtaining a variety of morphological structures. These characteristics allow the exploration of silk for biomedical applications and as a platform for drug delivery. We have reviewed silk structures that can be used for local and systemic drug delivery for use in cancer therapy. After a short description of the most studied silks, we discuss the advantages of using silk for drug delivery. The tables summarize the descriptions of silk structures for the local and systemic transport of anticancer drugs. The most popular techniques for silk particle preparation are presented. Further prospects for using silk as a drug carrier are considered. The application of various silk biomaterials can improve cancer treatment by the controllable delivery of chemotherapeutics, immunotherapeutics, photosensitizers, hormones, nucleotherapeutics, targeted therapeutics (e.g., kinase inhibitors), and inorganic nanoparticles, among others.

Polymeric prodrugs conjugated with reduction-sensitive dextran–camptothecin and pH-responsive dextran–doxorubicin: an effective combinatorial drug delivery platform for cancer therapy

2016 ◽  
Vol 7 (25) ◽  
pp. 4198-4212 ◽  
Author(s):  
Dongling Cao ◽  
Jinlin He ◽  
Jiaying Xu ◽  
Mingzu Zhang ◽  
Lin Zhao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Anticancer Activity ◽  
Ph Responsive ◽  
Delivery Platform ◽  
Stimuli Sensitive

Two types of stimuli-sensitive polymeric prodrugs for combinatorial cancer therapy have been prepared and found to exhibit favorable anticancer activity in vitro and in vivo.

Sign in / Sign up

Export Citation Format

Share Document