Smart pH/Redox Dual-Responsive Nanogels for On-Demand Intracellular Anticancer Drug Release

2016 ◽  
Vol 8 (12) ◽  
pp. 7729-7738 ◽  
Author(s):  
Hao Yang ◽  
Qin Wang ◽  
Shan Huang ◽  
Ai Xiao ◽  
Fuying Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
On Demand ◽  
Dual Responsive

Folate-conjugated dually responsive micelles for targeted anticancer drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (42) ◽  
pp. 35658-35667 ◽  
Author(s):  
Lingling Zhao ◽  
Yajuan Zhang ◽  
Jia Shao ◽  
Hongze Liang ◽  
Haining Na ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Anticancer Activity ◽  
Anticancer Drug ◽  
Anticancer Drug Delivery ◽  
Dual Responsive

Folate-conjugated dual-responsive micelles were developed, sustained and sensitive drug release from the drug loaded micelles was observed. Folate-targeted micelles showed higher anticancer activity and enhanced cellar uptake than non-targeted ones.

ATP triggered drug release and DNA co-delivery systems based on ATP responsive aptamers and polyethylenimine complexes

2016 ◽  
Vol 4 (21) ◽  
pp. 3832-3841 ◽  
Author(s):  
Guan-Hai Wang ◽  
Guo-Liang Huang ◽  
Yi Zhao ◽  
Xing-Xiang Pu ◽  
Tong Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
Delivery Systems ◽  
On Demand ◽  
Triggered Drug Release

An ATP-responsive nanocarrier based on PEI and aptamers complexes was designed for anticancer drug and DNA co-delivery. The nanocarrier displayed on-demand drug release and effective gene capability.

Cancer cell membrane-coated nanogels as redox/pH dual-responsive drug carrier for tumor-targeted therapy

2021 ◽  
Author(s):  
Junjie Deng ◽  
Weide Xu ◽  
Jilong Wang ◽  
Qinghua Li ◽  
Chenghu Wu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Therapy ◽  
Side Effects ◽  
Drug Release ◽  
Cell Membrane ◽  
Cancer Cell ◽  
Drug Carrier ◽  
On Demand ◽  
Dual Responsive

Nanocarriers have shown great advantages in increasing the efficiency of drug delivery and reducing the side effects. However, the lack of targeting and on-demand drug release will seriously limit their...

scholarly journals Anticancer Drug Release System Based on Hollow Silica Nanocarriers Triggered by Tumor Cellular Microenvironments

ACS Omega ◽  
2020 ◽  
Author(s):  
Shaoxin Deng ◽  
Cheng-Xing Cui ◽  
Lingyao Duan ◽  
Linfeng Hu ◽  
Xiaoxun Yang ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
Hollow Silica ◽  
Release System ◽  
Drug Release System ◽  
Cellular Microenvironments

scholarly journals Polymerisation-induced self-assembly (PISA) as a straightforward formulation strategy for stimuli-responsive drug delivery systems and biomaterials: recent advances

2021 ◽  
Vol 9 (1) ◽  
pp. 38-50
Author(s):  
Hien Phan ◽  
Vincenzo Taresco ◽  
Jacques Penelle ◽  
Benoit Couturaud
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Amphiphilic Block Copolymers ◽  
Stimuli Responsive ◽  
Site Specific ◽  
On Demand ◽  
Redox Agents

Stimuli-responsive amphiphilic block copolymers obtained by PISA have emerged as promising nanocarriers for enhancing site-specific and on-demand drug release in response to a range of stimuli such as pH, redox agents, light or temperature.

scholarly journals Controlled drug release to cancer cells from modular one-photon visible light-responsive micellar system

2016 ◽  
Vol 52 (69) ◽  
pp. 10525-10528 ◽  
Author(s):  
Saemi O. Poelma ◽  
Seung Soo Oh ◽  
Sameh Helmy ◽  
Abigail S. Knight ◽  
G. Leslie Burnett ◽  
...  
Keyword(s):  
Drug Release ◽  
Visible Light ◽  
Small Molecules ◽  
Cancer Cells ◽  
Controlled Drug Release ◽  
Micellar System ◽  
On Demand ◽  
System P

We present a one-photon visible light-responsive micellar system for efficient, on-demand delivery of small molecules.

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