Paper-based electrochemical immunosensor for carcinoembryonic antigen based on three dimensional flower-like gold electrode and gold-silver bimetallic nanoparticles

2014 ◽  
Vol 147 ◽  
pp. 650-656 ◽  
Author(s):  
Guoqiang Sun ◽  
Ya-nan Ding ◽  
Chao Ma ◽  
Yan Zhang ◽  
Shenguang Ge ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Gold Electrode ◽  
Bimetallic Nanoparticles ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Gold Silver

scholarly journals Sensitive electrochemical immunosensor based on three-dimensional nanostructure gold electrode

2015 ◽  
pp. 2219 ◽  
Author(s):  
Guangxian Zhong ◽  
Ruilong Lan ◽  
Wenxin Zhang ◽  
Feihuan Fu ◽  
Huaping Peng ◽  
...  
Keyword(s):  
Gold Electrode ◽  
Three Dimensional ◽  
Electrochemical Immunosensor

scholarly journals An Electrochemical Immunosensor for Sensitive Detection of the Tumor Marker Carcinoembryonic Antigen (CEA) Based on Three-Dimensional Porous Nanoplatinum/Graphene

Micromachines ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 660 ◽  
Author(s):  
Aihua Jing ◽  
Qiong Xu ◽  
Wenpo Feng ◽  
Gaofeng Liang
Keyword(s):  
Tumor Marker ◽  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Platinum Metal ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Diagnosis Of Cancer ◽  
Wet Chemical ◽  
Secondary Antibodies

Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. The quantitative detection of a low concentration of CEA has important medical significance. In this study, three-dimensional porous graphene-oxide-supported platinum metal nanoparticles (3DPt/HGO) composites were prepared by a wet chemical method and modified on an electrode with enhanced conductivity, a large surface area, and good adsorption of immobilizing antibodies (Ab1). Horseradish peroxidase (HRP)-functionalized Au nanoparticles were fabricated to label the secondary antibodies (Ab2). The proposed immunosensor showed a good linear relationship in the range of 0.001–150 ng/mL for CEA and a detection limit of 0.0006 ng/mL. The immunosensor had high sensitivity, good stability and reproducibility, and has great application prospects for the clinical diagnosis of cancer.

Application of three-dimensional flower-like nanomaterials in the fabrication of sandwich-type electrochemical immunosensors

RSC Advances ◽  
2015 ◽  
Vol 5 (107) ◽  
pp. 88160-88165 ◽  
Author(s):  
Yulan Wang ◽  
Yan Li ◽  
Lihua Hu ◽  
Xiang Ren ◽  
Bin Du ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Electrochemical Immunosensors ◽  
Sandwich Type

A novel and ultrasensitive sandwich-type electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA) in this work.

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Multi-walled carbon nanotubes–chitosan with a branched structure modified with ferrocenecarboxylic acid for carcinoembryonic antigen detection

2015 ◽  
Vol 7 (23) ◽  
pp. 10032-10039 ◽  
Author(s):  
Taotao Feng ◽  
Xiuwen Qiao ◽  
Haining Wang ◽  
Zhao Sun ◽  
Chenglin Hong
Keyword(s):  
Carbon Nanotubes ◽  
Carcinoembryonic Antigen ◽  
Modified Electrode ◽  
Electrochemical Immunosensor ◽  
Antigen Detection ◽  
Multi Walled Carbon Nanotubes ◽  
Ferrocenecarboxylic Acid ◽  
Branched Structure ◽  
Walled Carbon Nanotubes

A novel electrochemical immunosensor for the detection of CEA was proposed based on Fc-COOH connected to the branched structure of a MWCNT–CS complex modified electrode.

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