scholarly journals Sensitive electrochemical immunosensor based on three-dimensional nanostructure gold electrode

2015 ◽  
pp. 2219 ◽  
Author(s):  
Guangxian Zhong ◽  
Ruilong Lan ◽  
Wenxin Zhang ◽  
Feihuan Fu ◽  
Huaping Peng ◽  
...  
Keyword(s):  
Gold Electrode ◽  
Three Dimensional ◽  
Electrochemical Immunosensor

scholarly journals Sandwich Electrochemical Immunosensor for Early Detection of Tuberculosis Based on Graphene/Polyaniline-Modified Screen-Printed Gold Electrode

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 3926 ◽  
Author(s):  
Umi Mohd Azmi ◽  
Nor Yusof ◽  
Norzila Kusnin ◽  
Jaafar Abdullah ◽  
Siti Suraiya ◽  
...  
Keyword(s):  
Gold Electrode ◽  
Differential Pulse ◽  
Sample Volume ◽  
Electrochemical Immunosensor ◽  
X Ray ◽  
Sandwich Type ◽  
Pulse Voltammetry ◽  
Culture Filtrate Protein ◽  
Cast Technique ◽  
Screen Printed

A rapid and sensitive sandwich electrochemical immunosensor was developed based on the fabrication of the graphene/polyaniline (GP/PANI) nanocomposite onto screen-printed gold electrode (SPGE) for detection of tuberculosis biomarker 10-kDa culture filtrate protein (CFP10). The prepared GP/PANI nanocomposite was characterized using Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM). The chemical bonding and morphology of GP/PANI-modified SPGE were studied by Raman spectroscopy and FESEM coupled with energy dispersive X-ray spectroscopy, respectively. From both studies, it clearly showed that GP/PANI was successfully coated onto SPGE through drop cast technique. Cyclic voltammetry was used to study the electrochemical properties of the modified electrode. The effective surface area for GP/PANI-modified SPGE was enhanced about five times compared with bare SPGE. Differential pulse voltammetry was used to detect the CFP10 antigen. The GP/PANI-modified SPGE that was fortified with sandwich type immunosensor exhibited a wide linear range (20–100 ng/mL) with a low detection limit of 15 ng/mL. This proposed electrochemical immunosensor is sensitive, low sample volume, rapid and disposable, which is suitable for tuberculosis detection in real samples.

scholarly journals Dendrimers as Soft Nanomaterials for Electrochemical Immunosensors

Nanomaterials ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 1745 ◽  
Author(s):  
Alfredo Sánchez ◽  
Anabel Villalonga ◽  
Gonzalo Martínez-García ◽  
Concepción Parrado ◽  
Reynaldo Villalonga
Keyword(s):  
Pharmaceutical Analysis ◽  
State Of The Art ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
High Impact ◽  
Branched Polymers ◽  
Electrochemical Immunosensors ◽  
Signal Production ◽  
Poly Propylene ◽  
Affinity Biosensors

Electrochemical immunosensors are antibody-based affinity biosensors with a high impact on clinical, environmental, food, and pharmaceutical analysis. In general, the analytical performance of these devices is critically determined by the materials and reagents used for their construction, signal production and amplification. Dendrimers are monodisperse and highly branched polymers with three-dimensional structures widely employed as “soft” nanomaterials in electrochemical immunosensor technology. This review provides an overview on the state-of-the-art in dendrimer-based electrochemical immunosensors, focusing on those using polyamidoamine and poly (propylene imine) dendrimers. Special emphasis is given to the most original methods recently reported for the construction of immunosensor architectures incorporating dendrimers, as well as to novel sensing approaches based on dendrimer-assisted signal enhancement strategies.

An electrochemical immunosensor for ochratoxin A based on immobilization of antibodies on diazonium-functionalized gold electrode

2009 ◽  
Vol 54 (8) ◽  
pp. 2180-2184 ◽  
Author(s):  
Abd-Elgawad Radi ◽  
Xavier Muñoz-Berbel ◽  
Montserrat Cortina-Puig ◽  
Jean-Louis Marty
Keyword(s):  
Ochratoxin A ◽  
Gold Electrode ◽  
Electrochemical Immunosensor
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