Sandwich-type electrochemical immunosensor constructed using three-dimensional lamellar stacked CoS2@C hollow nanotubes prepared by template-free method to detect carcinoembryonic antigen

2019 ◽  
Vol 1088 ◽  
pp. 54-62 ◽  
Author(s):  
Chaoyun Ma ◽  
Chulei Zhao ◽  
Wenjun Li ◽  
Yiju Song ◽  
Chenglin Hong ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Sandwich Type ◽  
Template Free

Application of three-dimensional flower-like nanomaterials in the fabrication of sandwich-type electrochemical immunosensors

RSC Advances ◽  
2015 ◽  
Vol 5 (107) ◽  
pp. 88160-88165 ◽  
Author(s):  
Yulan Wang ◽  
Yan Li ◽  
Lihua Hu ◽  
Xiang Ren ◽  
Bin Du ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Electrochemical Immunosensors ◽  
Sandwich Type

A novel and ultrasensitive sandwich-type electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA) in this work.

A three-dimensional CoNi-MOF nanosheet array-based immunosensor for sensitive monitoring of human chorionic gonadotropin with core–shell ZnNi-MOF@Nile Blue nanotags

The Analyst ◽  
2020 ◽  
Vol 145 (24) ◽  
pp. 8097-8103
Author(s):  
Wenbo Lu ◽  
Zi-Ang Chen ◽  
Ming Wei ◽  
Xiaowei Cao ◽  
Xuping Sun
Keyword(s):  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Nile Blue ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Core Shell ◽  
Nanosheet Array ◽  
Sandwich Type

A sandwich-type electrochemical immunosensor for HCG detection based on a CoNi-MOF nanosheet-array and Nile Blue@ZnNi-MOF spheres is successfully exploited.

scholarly journals An Electrochemical Immunosensor for Sensitive Detection of the Tumor Marker Carcinoembryonic Antigen (CEA) Based on Three-Dimensional Porous Nanoplatinum/Graphene

Micromachines ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 660 ◽  
Author(s):  
Aihua Jing ◽  
Qiong Xu ◽  
Wenpo Feng ◽  
Gaofeng Liang
Keyword(s):  
Tumor Marker ◽  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Platinum Metal ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Diagnosis Of Cancer ◽  
Wet Chemical ◽  
Secondary Antibodies

Carcinoembryonic antigen (CEA) is an important broad-spectrum tumor marker. The quantitative detection of a low concentration of CEA has important medical significance. In this study, three-dimensional porous graphene-oxide-supported platinum metal nanoparticles (3DPt/HGO) composites were prepared by a wet chemical method and modified on an electrode with enhanced conductivity, a large surface area, and good adsorption of immobilizing antibodies (Ab1). Horseradish peroxidase (HRP)-functionalized Au nanoparticles were fabricated to label the secondary antibodies (Ab2). The proposed immunosensor showed a good linear relationship in the range of 0.001–150 ng/mL for CEA and a detection limit of 0.0006 ng/mL. The immunosensor had high sensitivity, good stability and reproducibility, and has great application prospects for the clinical diagnosis of cancer.

Sandwich-type electrochemical immunosensor for carcinoembryonic antigen detection based on the cooperation of a gold–vertical graphene electrode and gold@silica–methylene blue

2020 ◽  
Vol 8 (2) ◽  
pp. 298-307 ◽  
Author(s):  
Siyu Zheng ◽  
Mingji Li ◽  
Hongji Li ◽  
Cuiping Li ◽  
Penghai Li ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Immunosensor ◽  
Antigen Detection ◽  
Graphene Electrode ◽  
Sandwich Type

In this study, a sandwich-type electrochemical (EC) immunosensor was proposed to detect a carcinoembryonic antigen (CEA) based on Au–graphene and Au@SiO2–methylene blue (MB).

A sandwich-type electrochemical immunosensor using polythionine/AuNPs nanocomposites as label for ultrasensitive detection of carcinoembryonic antigen

2019 ◽  
Vol 9 (5) ◽  
pp. 444-450 ◽  
Author(s):  
Yuxuan Lai ◽  
Hao Huang ◽  
Zhihuan Xia ◽  
Song Li ◽  
Yan Deng ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Surface Area ◽  
Chemical Reduction ◽  
Electrochemical Immunosensor ◽  
Cancer Diagnostics ◽  
Active Surface Area ◽  
Layer By Layer ◽  
Glass Carbon Electrode ◽  
Wide Range ◽  
Sandwich Type

A sandwich-type electrochemical immunosensor was developed in this study for sensitive detection of carcinoembryonic antigen (CEA) based on rGO/CS/AuNPs as a sensing platform and PTh-Au composites as signal labels. Reduced graphene oxide (rGO), Chitosan (CS) and AuNPs were layer by layer modified on glass carbon electrode (GCE), which effectively enhanced electron transfer and provided excellent large electrochemical active surface area. Polythionine-Au composites prepared by chemical reduction method greatly amplified electrochemical signal with high conductivity and large surface area. The prepared immunosensor showed high sensitivity, good stability and selectivity for detection of CEA with a wide range of 0.3 ng/mL to 30 ng/mL (R2 = 0.9972) and a detection limit as low as 0.1471 pg/mL. Furthermore, this sandwich-type immunosensor might be as a versatile platform for reliable early cancer diagnostics clinical.

Sensitive detection of carcinoembryonic antigen (CEA) by a sandwich-type electrochemical immunosensor using MOF-Ce@HA/Ag-HRP-Ab2 as a nanoprobe

2020 ◽  
Vol 31 (18) ◽  
pp. 185605 ◽  
Author(s):  
Wenjun Li ◽  
Chaoyun Ma ◽  
Yiju Song ◽  
Chenglin Hong ◽  
Xiuwen Qiao ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Electrochemical Immunosensor ◽  
Sensitive Detection ◽  
Sandwich Type
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