Improvement of DNA damage protection and antioxidant activity of biotransformed pearl millet (Pennisetum glaucum) cultivar PUSA-415 using Aspergillus oryzae MTCC 3107

2016 ◽  
Vol 8 ◽  
pp. 221-227 ◽  
Author(s):  
Raj Kumar Salar ◽  
Sukhvinder Singh Purewal
Keyword(s):  
Dna Damage ◽  
Antioxidant Activity ◽  
Pearl Millet ◽  
Aspergillus Oryzae ◽  
Pennisetum Glaucum ◽  
Dna Damage Protection ◽  
Damage Protection

Solid-state fermentation of pearl millet with Aspergillus oryzae and Rhizopus azygosporus: effects on bioactive profile and DNA damage protection activity

2019 ◽  
Vol 14 (1) ◽  
pp. 150-162 ◽  
Author(s):  
Sukhvinder Singh Purewal ◽  
Raj Kumar Salar ◽  
Manpreet Singh Bhatti ◽  
Kawaljit Singh Sandhu ◽  
Surender Kumar Singh ◽  
...  
Keyword(s):  
Dna Damage ◽  
Solid State ◽  
Pearl Millet ◽  
Aspergillus Oryzae ◽  
Solid State Fermentation ◽  
Protection Activity ◽  
Dna Damage Protection ◽  
Damage Protection

Fermented pearl millet: a product with enhanced bioactive compounds and DNA damage protection activity

2019 ◽  
Vol 13 (2) ◽  
pp. 1479-1488 ◽  
Author(s):  
Sukhvinder Singh Purewal ◽  
Kawaljit Singh Sandhu ◽  
Raj Kumar Salar ◽  
Pinderpal Kaur
Keyword(s):  
Dna Damage ◽  
Pearl Millet ◽  
Bioactive Compounds ◽  
Protection Activity ◽  
Dna Damage Protection ◽  
Damage Protection

Enhanced total phenolic and isoflavone aglycone content, antioxidant activity and DNA damage protection of soybeans processed by solid state fermentation with Rhizopus oligosporus RT-3

RSC Advances ◽  
2016 ◽  
Vol 6 (35) ◽  
pp. 29741-29756 ◽  
Author(s):  
Yu Xiao ◽  
Juan Fan ◽  
Yulian Chen ◽  
Xin Rui ◽  
Qiuqin Zhang ◽  
...  
Keyword(s):  
Dna Damage ◽  
Antioxidant Activity ◽  
Solid State ◽  
Solid State Fermentation ◽  
Total Phenolic ◽  
Rhizopus Oligosporus ◽  
Short Time ◽  
Dna Damage Protection ◽  
Damage Protection

In this study,Rhizopus oligosporusRT-3, which was first isolated in our group, was used for solid state fermentation of soybeans (R. oligosporus-fermented soybeans, RFS) in a short time (22 h).

scholarly journals COMPARATIVE STUDY AGAINST OXIDATIVE STRESS AND DNA DAMAGE PROTECTION ACTIVITY OF THE DIFFERENT EXTRACTS OF TUBERS OF ARISAEMA TORTUOSUM (WALL.) SCHOTT.

2019 ◽  
pp. 166-170
Author(s):  
PRIYANKA CHAKRABORTY ◽  
NRIPENDRA NATH BALA ◽  
SUDIPTA DAS
Keyword(s):  
Dna Damage ◽  
Antioxidant Activity ◽  
Comparative Study ◽  
Methanolic Extract ◽  
Total Phenolic ◽  
Flavonoid Compounds ◽  
Protection Activity ◽  
Dna Damage Protection ◽  
Damage Protection

Objective: Our main aim is to evaluate the comparative in vitro antioxidant and DNA damage protection activity study with different extracts of tubers of Arisaema tortuosum. Methods: A. tortuosum (Wall.) Schott. (Araceae family) is commonly known as whipcord cobra lily, used in India as traditional medicine. In vitro, antioxidant activity was done by six methods including determination of total phenolic and total flavonoid compounds. The DNA damage was estimated by standard diphenylamine reaction. Results: Methanolic extract of tubers of A. tortuosum has been found rich in phenolic and flavonoid compounds when compared with other extracts. Methanolic extract of rhizomes of A. tortuosum showed potent antioxidant activity at a concentration of 400 μg/mL and potent the DNA damage protecting activity at a concentration of 50 μg/mL. Conclusion: Comparative study against oxidative damage and protection to the DNA damage protection activity of the different extracts of tubers of A. tortuosum (Wall.) Schott. showed that methanolic extract is most potent, though ethyl acetate extract also showed activity.

scholarly journals Evaluation of Antioxidant and DNA Damage Protection Activity of the Hydroalcoholic Extract ofDesmostachya bipinnataL. Stapf

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Upendarrao Golla ◽  
Solomon Sunder Raj Bhimathati
Keyword(s):  
Dna Damage ◽  
Antioxidant Activity ◽  
Yeast Cells ◽  
Dependent Manner ◽  
Hydroalcoholic Extract ◽  
Dose Dependent ◽  
Protection Activity ◽  
Dna Damage Protection ◽  
Damage Protection

Desmostachya bipinnataStapf (Poaceae/Gramineae) is an official drug of ayurvedic pharmacopoeia. Various parts of this plant were used extensively in traditional and folklore medicine to cure various human ailments. The present study was aimed to evaluate the antioxidant and DNA damage protection activity of hydroalcoholic extract ofDesmostachya bipinnatabothin vitroandin vivo, to provide scientific basis for traditional usage of this plant. The extract showed significant antioxidant activity in a dose-dependent manner with an IC50value of264.18±3.47 μg/mL in H2O2scavenging assay and prevented the oxidative damage to DNA in presence of DNA damaging agent (Fenton’s reagent) at a concentration of 50 μg/mL. Also, the presence of extract protected yeast cells in a dose-dependent manner against DNA damaging agent (Hydroxyurea) in spot assay. Moreover, the presence of extract exhibited significant antioxidant activityin vivoby protecting yeast cells against oxidative stressing agent (H2O2). Altogether, the results of current study revealed thatDesmostachya bipinnatais a potential source of antioxidants and lends pharmacological credence to the ethnomedical use of this plant in traditional system of medicine, justifying its therapeutic application for free-radical-induced diseases.

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