Morphofunctional characteristics of connective tissue in emotionally stressed august and wistar rats

1995 ◽  
Vol 119 (6) ◽  
pp. 548-550 ◽  
Author(s):  
V. V. Serov ◽  
I. V. Tomilina ◽  
K. V. Sudakov
Keyword(s):  
Connective Tissue ◽  
Wistar Rats ◽  
August And Wistar Rats

scholarly journals A Comparative Study of Biocompatibility in Rat Connective Tissue of a New Mineral Trioxide Compound (Theracal) versus MTA and a Bioactive G3 Glass

2021 ◽  
Vol 10 (12) ◽  
pp. 2536
Author(s):  
Jesús Mena-Álvarez ◽  
Cristina Rico-Romano ◽  
Carlos Gutiérrez-Ortega ◽  
Pablo Arias-Sanz ◽  
Javier Castro-Urda
Keyword(s):  
Connective Tissue ◽  
Inflammatory Reaction ◽  
Direct Contact ◽  
Wistar Rats ◽  
Tissue Response ◽  
New Mineral ◽  
Exact Test ◽  
Dorsal Area ◽  
Subcutaneous Connective Tissue ◽  
Hematoxylin Eosin

The aim of this paper was to assess the differences in tissue response to implantation during 15, 30 and 45 days in the subcutaneous connective tissue of Wistar rats from three biomaterials: Angelus MTA®, Theracal LC®, and Angelus MTA® to which 25% bioglass G3 was added. Twenty-four Wistar rats were used, the materials were inserted into the rat’s dorsal area in silicone tubes 5 mm long by 1.5 mm diameter. Histological reaction was assessed at 15, 30, and 45 days after implantation. They were then stained with hematoxylin eosin and evaluated by two observers. Data were analyzed using Fisher’s exact test and Mann–Whitney’s U test was used to determine the association between variables. Angelus MTA induced the formation of dystrophic calcifications twice as much as Theracal LC (p < 0.05). The addition of G3 did not affect the greater or lesser occurrence of calcifications (p > 0.05). Theracal LC and MTA plus G3 caused an inflammatory reaction, which was chronic at 15 days and decreased in intensity, almost disappearing after 45 days. Theracal LC, as well as Angelus MTA plus G3, were well tolerated when implanted in the subcutaneous connective tissue of rat. Histologically, no inconvenience was found for the use by direct contact of Theracal LC, and the mixture of MTA with 25% bioactive glass G3, in the tissue of Wistar rats.

Differences between August and Wistar rats in stress reactions and in the development of adaptation to stress

1996 ◽  
Vol 122 (2) ◽  
pp. 790-792
Author(s):  
M. G. Pshennikova ◽  
L. Yu. Golubeva ◽  
B. A. Kuznetsova ◽  
M. V. Shimkovich ◽  
E. V. Malysheva ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Adaptation To Stress ◽  
Stress Reactions ◽  
August And Wistar Rats

Implications of Creatinine and ALP in the Induction of Osteoporosis by Ovariectomy in Female Wistar Rats

2017 ◽  
Vol 68 (8) ◽  
pp. 1799-1803
Author(s):  
Adela Cristina Lazar ◽  
Radu Lacatus ◽  
Robert Purdoiu ◽  
Lucia Bel ◽  
Orsolya Sarpataki ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Connective Tissue ◽  
Wistar Rats ◽  
Inflammatory Infiltrate ◽  
Mononuclear Cells ◽  
Treatment Plan ◽  
Accurate Information ◽  
Fibrous Connective Tissue ◽  
Microscopic Evaluation ◽  
Female Wistar Rats

Histological and biochemical assessment of maxillary bone necrosis induced by therapy with two bisphosphonate types used to treat osteoporosis induced in female Wistar rats, evaluation of effects on creatinine and ALP values at different time intervals. Female Wistar rats were ovariectomized to induce osteoporosis. Blood tests for ALP and creatinine were conducted. They received two types of bisphosphonates. Dental extraction was performed in each rat separately; finally, the rats were euthanized. Microscopic evaluation of the tissue fragments collected from the groups of rats was performed for the following parameters: degree of osteonecrosis, bone resorption, inflammatory infiltrate with neutrophils and mononuclear cells, number of osteoclasts, degree of proliferation of fibrous connective tissue, and local neovascularization. The biochemical and subsequently histological investigations for osteonecrosis of the jaw associated with bisphosphonate therapy in rats with induced osteoporosis provide accurate information about the extent of osteonecrosis, bone resorption, inflammatory infiltrate with mononuclear cells and neutrophils, number of osteoclasts, degree of proliferation of fibrous connective tissue, and local neovascularization. This is necessary for positive and differential diagnosis and for the treatment plan.

Activity of Heme Synthesis Enzymes in the Bone Marrow and Liver of August and Wistar Rats During the Neonatal Period and After Acute Postnatal Hypoxia

2015 ◽  
Vol 160 (2) ◽  
pp. 193-195
Author(s):  
S. I. Kolesnikov ◽  
A. S. Popova ◽  
L. I. Krupitskaya ◽  
A. I. Sinitskii ◽  
L. I. Kolesnikova
Keyword(s):  
Bone Marrow ◽  
Wistar Rats ◽  
Neonatal Period ◽  
August And Wistar Rats ◽  
Heme Synthesis

scholarly journals Biocompatibility of two types of resins for prosthetic usage

2010 ◽  
Vol 10 (2) ◽  
Author(s):  
Sigmar M. Rode ◽  
Bruno N. Cavalcanti ◽  
Vanessa Ferrielo ◽  
Miriam R. Faria ◽  
Nelson Villa
Keyword(s):  
Connective Tissue ◽  
Light Microscopy ◽  
Visible Light ◽  
Wistar Rats ◽  
Base Material ◽  
Microscopy Observation ◽  
Denture Base ◽  
Biological Compatibility ◽  
Materials Used ◽  
Compatibility Of Materials

The purpose of the present study was evaluate the biological compatibility of materials used to manufacture prosthetic appliances. A heat-polymerized colorless resin and one visible light-cured denture base material were tested by the implantation of probe discs, in the dorsal connective tissue of 12 Wistar rats. The animals were sacrificed at 7, 14, 21 and 28 days after implantation. The specimens were prepared for light microscopy observation. It was noted that either after light microscopy observations, both resins demonstrated a good level of biocompatibility within the connective tissue of the dorsum of the animals studied.

scholarly journals TOXIC-ALIMENTARY MODEL OF LIVER CIRRHOSIS IN RATS

2018 ◽  
pp. 62-66
Author(s):  
B. B. Osipov ◽  
A. N. Lyzikov ◽  
A. G. Skuratov ◽  
A. A. Prizentsov
Keyword(s):  
Liver Cirrhosis ◽  
Carbon Tetrachloride ◽  
Liver Fibrosis ◽  
Liver Injury ◽  
Connective Tissue ◽  
Wistar Rats ◽  
Control Group ◽  
Injection Control ◽  
Toxic Liver Injury ◽  
Experimental Group

Objective: to design an experimental model of liver cirrhosis in rats and to compare it with the carbon tetrachloride model of liver injury. Material and methods. White Wistar rats (n=30) were used as objects for modeling of toxic liver injury. The modeling was performed by the designed toxic-alimentary method (experimental group, n=15) and by means of the carbon tetrachloride injection (control group, n=15). The animals were sacrificed at different terms (8, 12 weeks after start of the modeling and 3 months after termination of the modeling), and the morphological and morphometric state of the liver was studied. Results. The designed toxic-alimentary model of liver injury leads to liver cirrhosis 8 weeks after start of the modeling (reproducibility - 93.3 %). The reproducibility of liver cirrhosis in case of using the carbon tetrachloride model 8 weeks after start of the modeling is 26.7%, which is proved by statistically lower thickness of connective-tissue septa in the liver in the control group in comparison with the experimental group (p=0.016, Mann Whitney U test). The designed toxic-alimentary method ensures shorter timing of the modeling of liver cirrhosis (from 12 weeks in the control group to 8 weeks in the experimental group) and also lower reversibility of liver fibrosis signs 3 months after termination of the modeling in comparison with the carbon tetrachloride model of liver injury. Conclusions. The designed toxic-alimentary model of liver injury leads to liver cirrhosis 8 weeks after start of the modeling. The developed model ensures shorter timing of the modeling of liver cirrhosis, increased reproducibility as well as lower reversibility of liver fibrosis signs 3 months after termination of the modeling in comparison with the carbon tetrachloride model of liver injury.

scholarly journals Comparison of Rat Connective Tissue Response to BioMTA, Angelus MTA, and Root MTA

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Marzieh Alimohammadi ◽  
Sina Mirzaee-Rad ◽  
Farideh Feizi ◽  
Hadi Shirzad Juybari ◽  
Akam Saeidi ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Wistar Rats ◽  
Tissue Response ◽  
Fibrous Capsule ◽  
Control Group ◽  
Capsule Formation ◽  
Significant Difference ◽  
Male Wistar Rats ◽  
The Difference ◽  
Fibrous Capsule Formation

Due to the widespread use of MTA in dentistry and various brands of this product, we decided to compare the three brands available in the country market by their biocompatibility. We divided 20 male Wistar rats into four groups. After local anesthesia and washing, we made two incisions on both sides (4 incisions in total). The experimental groups were Angelus MTA (Angelus, Brazil), BioMTA (CERKAMED, Poland), Root MTA (Dr. Lotfi, Tabriz, Iran), and the control group. The resulting paste was placed in a tube and implanted subcutaneously into male Wistar rats. Wistar rats were sacrificed 7, 15, 30, and 60 days later, with high anesthetic doses. The sample implanted in 10% formalin was stabilized after tissue processing and H&E staining under a microscope. The inflammatory reaction in the tissues received different scores at the beginning of the tube opening. BioMTA had the highest inflammatory response among the groups, but the difference was not statistically significant ( p  > 0.05). Also, there was no significant difference between the groups’ granulation and calcification ( p  < 0.05). There was a significant difference between BioMTA, Angelus MTA, Root MTA, and control groups in fibrous capsule formation ( p  < 0.05). Angelus MTA showed the lowest mean fibrous capsule formation in all periods. The effects of Angelus MTA, Root MTA, and BioMTA on connective tissue were investigated and compared. According to this study, these materials have good biocompatibility. According to the findings and statistical analysis, Angelus MTA has the most biocompatibility.

The Dura as Anti-Adhesive Coating Polypropylene Implant for Laparoscopic Hernioplasty

10.12737/5948 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-5
Author(s):  
Воробейчук ◽  
G. Vorobeychuk ◽  
Драйер ◽  
M. Drayer ◽  
Тлибекова ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Wistar Rats ◽  
Research Work ◽  
Parietal Peritoneum ◽  
Grid Structure ◽  
Adhesive Properties ◽  
Internal Organs ◽  
Laparoscopic Hernioplasty ◽  
Adhesive Coating

This study presents the results of investigation of anti-adhesive properties of the dura combined with polypropylene implant, and a composite mash with a hydrogellayer Parietex Composite. 40 Wistar rats were used for this research work. The study showed that the use of the dura as an anti-adhesive coating prevents fusion of the internal organs with the implant, and the polypropylene used as a mash basis, firmly fuses with the parietal peritoneum, promoting in growth of connective tissue in the grid structure. These results are comparable to results obtained using Parietex Composite.

scholarly journals Expanded polytetrafluoroethylene and polypropylene in the repairing of abdominal wall defects in Wistar rats: comparative study

2006 ◽  
Vol 21 (6) ◽  
pp. 409-415 ◽  
Author(s):  
Armando José d'Acampora ◽  
Fabrícia Slomski Joli ◽  
Ricardo Tramonte
Keyword(s):  
Connective Tissue ◽  
Abdominal Wall ◽  
Polypropylene Mesh ◽  
Wistar Rats ◽  
Fibrous Tissue ◽  
Microscopic Analysis ◽  
Surrounding Tissue ◽  
Control Group ◽  
Abdominal Wall Defects ◽  
Surgical Wound

PURPOSE: To compare the use of polypropylene and PTFE meshes in the treatment of incisional hernias made experimentally on Wistar rats. METHODS: The experiment used 24 Wistar rats divided into three cohorts: C-A (ressection of a segment of abdominal wall), E-A (ressection and placement of PTFEe mesh), E-B (resection and placement of polypropylene mesh). After 28 days, the mesh and the surrounding tissue were removed and submitted to macroscopic analysis (assessment of the abdominal wall for presence of abscess in the surgical wound and/or skin necrosis, and adhesions) as well as microscopic analysis (presence of fibrosis, necrosis and abscess, counting of macrophages, mononuclears and polymorphonuclears). RESULTS: Adhesions and abscesses in the surgical wound were observed more commonly associated to the group treated with PTFEe. The size of the fibrous tissue was greater in the group treated with polypropylene. Cohort E-A showed PTFEe mesh enveloped by organized fine connective tissue. No groups presented necrosis on the site of the insertion. The highest mononuclear inflammatory reaction occurred in association to PTFEe when compared to the control group, but the findings for the polypropylene mesh were also significant when compared to the control group. In the analysis of the results obtained for cohorts E-A and E-B, a minimal occurrence of polymorphonuclears was noticed in both groups, which indicates low tissue reactivity to both materials used in the present experiment. CONCLUSION: Even with epithelization and proliferation of connective tissue, anchorage between PTFEe and abdominal wall is insufficient, which can result in reherniations.

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