Hydrolytic and enzymatic degradation of poly(γ-glutamic acid) hydrogels and their application in slow-release systems for proteins

1996 ◽  
Vol 4 (4) ◽  
pp. 253-260 ◽  
Author(s):  
Kesuo Fan ◽  
Denis Gonzales ◽  
Martin Sevoian
Keyword(s):  
Glutamic Acid ◽  
Enzymatic Degradation ◽  
Slow Release

scholarly journals Polypseudorotaxane Formation of Randomly-Pegylated Insulin with Cyclodextrins: Slow Release and Resistance to Enzymatic Degradation

2009 ◽  
Vol 57 (5) ◽  
pp. 541-544 ◽  
Author(s):  
Taishi Higashi ◽  
Fumitoshi Hirayama ◽  
Shogo Misumi ◽  
Keiichi Motoyama ◽  
Hidetoshi Arima ◽  
...  
Keyword(s):  
Enzymatic Degradation ◽  
Slow Release ◽  
Pegylated Insulin

Enzymatic degradation of synthetic poly(.ALPHA.-amino acid) fibers. [1]. Poly(L-glutamic acid) fiber.

1987 ◽  
Vol 43 (9) ◽  
pp. 462-470 ◽  
Author(s):  
Toshio Hayashi ◽  
Juzo Takahashi ◽  
Akio Nakajima
Keyword(s):  
Amino Acid ◽  
Glutamic Acid ◽  
Enzymatic Degradation ◽  
Alpha Amino Acid

Nachweis und Bestimmung eines Hyaluronat-Protein-Komplexes in der Peritonealflüssigkeit von Ratten nach Injektion von Phytohämagglutinin / Occurence and Estimation of a Hyaluronate Protein Complex in the Peritoneal Fluid of Rats after Injection of Phytohemagglutinin

1972 ◽  
Vol 27 (4) ◽  
pp. 414-419 ◽  
Author(s):  
H. Greiling ◽  
W. Mohr ◽  
G. Beneke
Keyword(s):  
Amino Acids ◽  
Glutamic Acid ◽  
Aspartic Acid ◽  
Protein Complex ◽  
Intraperitoneal Injection ◽  
Peritoneal Fluid ◽  
Enzymatic Degradation ◽  
Cetylpyridinium Chloride ◽  
Maximum Amount

In the peritoneal fluid of rats hyaluronate is produced after intraperitoneal injection of phytohemagglutinin.The hyaluronate concentration was quantitated spectrophotometrically after enzymatic degradation by hyaluronatlyase and a maximum amount of 90 mg% hyaluronate was found after intraperitoneal injection. The production of hyaluronate after phytohemagglutinin injection is dependent on the time and concentration of the phytohemagglutinin. Maximum hyaluronate synthesis is about 48 h after phytohemagglutinin, after this time the hyaluronate concentration is decreased.After phytohemagglutinin stimulation we isolated a hyaluronate protein complex from the peritoneal fluid by cetylpyridinium chloride precipitation followed by chromatography on Biogel P-150. The dominating amino acids were aspartic acid and glutamic acid.

In vitro Enzymatic Degradation of Nanoparticles Prepared from Hydrophobically-Modified Poly(γ-glutamic acid)

2005 ◽  
Vol 5 (7) ◽  
pp. 598-602 ◽  
Author(s):  
Takami Akagi ◽  
Mariko Higashi ◽  
Tatsuo Kaneko ◽  
Toshiyuki Kida ◽  
Mitsuru Akashi
Keyword(s):  
Glutamic Acid ◽  
Enzymatic Degradation ◽  
Hydrophobically Modified

Polymer Drugs and Polymeric Drugs X: Slow Release of 5-Fluorouracil from Biodegradable Poly(γ-Glutamic Acid) and its Benzyl Ester Matrices

1998 ◽  
Vol 13 (4) ◽  
pp. 270-278 ◽  
Author(s):  
Akio Kishida ◽  
Kazunori Murakami ◽  
Hidetada Goto ◽  
Mitsuru Akashi ◽  
Hidetoshi Kubota ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Slow Release ◽  
Benzyl Ester ◽  
Polymeric Drugs ◽  
Biodegradable Poly ◽  
Polymer Drugs

Hydrolytic and Enzymatic Degradation of Nanoparticles Based on Amphiphilic Poly(γ-glutamic acid)-graft-l-Phenylalanine Copolymers

2006 ◽  
Vol 7 (1) ◽  
pp. 297-303 ◽  
Author(s):  
Takami Akagi ◽  
Mariko Higashi ◽  
Tatsuo Kaneko ◽  
Toshiyuki Kida ◽  
Mitsuru Akashi
Keyword(s):  
Glutamic Acid ◽  
Enzymatic Degradation
Sign in / Sign up

Export Citation Format

Share Document