Cation transport in normal human red cells treated with sulfhydryl compounds

1966 ◽  
Vol 22 (1) ◽  
pp. 32-33 ◽  
Author(s):  
G. D'Amico ◽  
G. Sirchia ◽  
S. Ferrone ◽  
M. Romagnoni
Keyword(s):  
Cation Transport ◽  
Red Cells ◽  
Normal Human ◽  
Sulfhydryl Compounds ◽  
Human Red Cells

scholarly journals The Action of Two Sulfhydryl Compounds on Normal Human Red Cells

Blood ◽  
1965 ◽  
Vol 25 (4) ◽  
pp. 502-510 ◽  
Author(s):  
GIROLAMO SIRCHIA ◽  
SOLDANO FERRONE ◽  
FRANCESCO MERCURIALI
Keyword(s):  
Mechanism Of Action ◽  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Red Cells ◽  
Experimental Conditions ◽  
Sh Groups ◽  
Normal Human ◽  
Sulfhydryl Compounds ◽  
Human Red Cells

Abstract Treatment of normal human red cells with AET and cysteine, under suitable experimental conditions, modifies them in such a way that their behavior in in vitro hemolysis tests becomes similar to that of the erythrocytes of paroxysmal nocturnal hemoglobinuria. It is felt that alteration of the red cells is due to the -SH groups possessed by both substances. A possible mechanism of action is hypothesized.

scholarly journals Observations on Certain Enzyme Activities of Normal Human Red Cells Treated with Sulfhydryl Compounds

Blood ◽  
1966 ◽  
Vol 28 (1) ◽  
pp. 98-101 ◽  
Author(s):  
GIROLAMO SIRCHIA ◽  
SOLDANO FERRONE ◽  
ROBERTO MILANI ◽  
FRANCESCO MERCURIALI
Keyword(s):  
Methylene Blue ◽  
Enzyme Activities ◽  
Lactic Acid Production ◽  
Acetylcholinesterase Activity ◽  
Red Cells ◽  
O2 Uptake ◽  
Normal Human ◽  
Glucose 6 Phosphate Dehydrogenase ◽  
Sulfhydryl Compounds ◽  
Human Red Cells

Abstract Some enzyme activities of normal human red cells treated with AET and cysteine have been investigated. Treated red cells showed low acetylcholinesterase activity and low O2 uptake in the presence of methylene blue; on the contrary, glucose-6-phosphate-dehydrogenase activity and lactic acid production in the presence of glucose were found to be normal. Results are briefly discussed.

scholarly journals The Action of Two Sulfhydryl Compounds on Normal Human Red Cells

Blood ◽  
1965 ◽  
Vol 26 (2) ◽  
pp. 234-234
Author(s):  
GIROLAMO SIRCHIA ◽  
SOLDANO FERRONE ◽  
FRANCESCO MERCURIALI
Keyword(s):  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Red Cells ◽  
First Line ◽  
Normal Human ◽  
Sulfhydryl Compounds ◽  
Human Red Cells

Abstract In the paper by G. Sirchia, S. Ferrone and F. Mercuriali: "The Action of Two Sulfhydryl Compounds on Normal Human Red Cells. Relationship to Red Cells of Paroxysmal Nocturnal Hemoglobinuria," published in BLOOD 25:502, 1965, a misprint appears. The first line on page 503 reads "for exactly 19 minutes" instead of "for exactly 9 minutes."

pH Dependent Hemolytic Systems. I. Their Relationship to Paroxysmal Nocturnal Hemoglobinuria

Blood ◽  
1961 ◽  
Vol 17 (1) ◽  
pp. 83-96 ◽  
Author(s):  
STANLEY YACHNIN ◽  
MITSUKO T. LAFORET ◽  
FRANK H. GARDNER
Keyword(s):  
Paroxysmal Nocturnal Hemoglobinuria ◽  
Proteolytic Enzymes ◽  
Red Cells ◽  
Red Cell ◽  
Cholera Vibrio ◽  
Normal Human ◽  
Ph Dependent ◽  
Kinetics Of ◽  
Insight Into ◽  
Human Red Cells

Abstract 1. Treatment of normal human red cells with various proteolytic enzymes, cholera vibrio filtrate, influenza virus, and periodate ion results in red cells susceptible to acid hemolysis in compatible normal human serum. 2. The kinetics of hemolysis of these artificially altered red cells resembles in many respects those observed in paroxysmal nocturnal hemoglobinuria (PNH). 3. While the observed differences in behavior between these artificially altered cells and PNH cells do not allow direct comparison, it is felt that these models may offer some clues in the understanding of PNH cell hemolysis, and some insight into the nature of the red cell lesion in paroxysmal nocturnal hemoglobinuria.

Normal Human Red Cells Treated in vitro with Cephalothin

1971 ◽  
Vol 45 (4) ◽  
pp. 245-249 ◽  
Author(s):  
S. Ferrone ◽  
G. Lambertenghi-Deliliers ◽  
T. Ranzi
Keyword(s):  
Red Cells ◽  
Normal Human ◽  
Human Red Cells
Sign in / Sign up

Export Citation Format

Share Document