scholarly journals Effects of deoxygenation on active and passive Ca2+ transport and cytoplasmic Ca2+ buffering in normal human red cells.

1993 ◽  
Vol 464 (1) ◽  
pp. 529-544 ◽  
Author(s):  
T Tiffert ◽  
Z Etzion ◽  
R M Bookchin ◽  
V L Lew
Blood ◽  
1961 ◽  
Vol 17 (1) ◽  
pp. 83-96 ◽  
Author(s):  
STANLEY YACHNIN ◽  
MITSUKO T. LAFORET ◽  
FRANK H. GARDNER

Abstract 1. Treatment of normal human red cells with various proteolytic enzymes, cholera vibrio filtrate, influenza virus, and periodate ion results in red cells susceptible to acid hemolysis in compatible normal human serum. 2. The kinetics of hemolysis of these artificially altered red cells resembles in many respects those observed in paroxysmal nocturnal hemoglobinuria (PNH). 3. While the observed differences in behavior between these artificially altered cells and PNH cells do not allow direct comparison, it is felt that these models may offer some clues in the understanding of PNH cell hemolysis, and some insight into the nature of the red cell lesion in paroxysmal nocturnal hemoglobinuria.


1971 ◽  
Vol 45 (4) ◽  
pp. 245-249 ◽  
Author(s):  
S. Ferrone ◽  
G. Lambertenghi-Deliliers ◽  
T. Ranzi

Blood ◽  
1965 ◽  
Vol 25 (4) ◽  
pp. 502-510 ◽  
Author(s):  
GIROLAMO SIRCHIA ◽  
SOLDANO FERRONE ◽  
FRANCESCO MERCURIALI

Abstract Treatment of normal human red cells with AET and cysteine, under suitable experimental conditions, modifies them in such a way that their behavior in in vitro hemolysis tests becomes similar to that of the erythrocytes of paroxysmal nocturnal hemoglobinuria. It is felt that alteration of the red cells is due to the -SH groups possessed by both substances. A possible mechanism of action is hypothesized.


1966 ◽  
Vol 22 (1) ◽  
pp. 32-33 ◽  
Author(s):  
G. D'Amico ◽  
G. Sirchia ◽  
S. Ferrone ◽  
M. Romagnoni

1996 ◽  
Vol 491 (3) ◽  
pp. 773-777 ◽  
Author(s):  
J E Raftos ◽  
R M Bookchin ◽  
V L Lew

1979 ◽  
Vol 76 (7) ◽  
pp. 3382-3386 ◽  
Author(s):  
N. S. Kosower ◽  
E. M. Kosower ◽  
G. L. Newton ◽  
H. M. Ranney

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