Provisional assignment ofMPI, PKM2, PGM3, andME1 to Chinese hamster chromosome 4

1984 ◽  
Vol 10 (1) ◽  
pp. 109-111 ◽  
Author(s):  
Raymond L. Stallings ◽  
Gerald M. Adair ◽  
Michael J. Siciliano
Keyword(s):  
Chinese Hamster ◽  
Chromosome 4 ◽  
Chinese Hamster Chromosome

Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4

1985 ◽  
Vol 11 (4) ◽  
pp. 391-395
Author(s):  
C. Edgar Hildebrand ◽  
Raymond L. Stallings ◽  
Frank J. Gonzalez ◽  
Daniel W. Nebert
Keyword(s):  
Gene Family ◽  
Chinese Hamster ◽  
Chromosome 4 ◽  
Cytochrome P 450 ◽  
Chinese Hamster Chromosome

Chromosome polymorphism involving heterochromatic blocks in Chinese hamster chromosome 9

1984 ◽  
Vol 38 (4) ◽  
pp. 257-264 ◽  
Author(s):  
F.A. Ray ◽  
M.F. Bartholdi ◽  
P.M. Kraemer ◽  
L.S. Cram
Keyword(s):  
Chinese Hamster ◽  
Chromosome 9 ◽  
Chromosome Polymorphism ◽  
Chinese Hamster Chromosome

GNAI3, GNAT2, AMPD2, GSTM are clustered in 120 kb of Chinese hamster Chromosome 1q

1996 ◽  
Vol 7 (6) ◽  
pp. 429-432 ◽  
Author(s):  
B. Baron ◽  
M. A. Fernandez ◽  
S. Carignon ◽  
F. Toledo ◽  
G. Buttin ◽  
...  
Keyword(s):  
Chinese Hamster ◽  
Chromosome 1Q ◽  
Chinese Hamster Chromosome

Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5

1982 ◽  
Vol 2 (10) ◽  
pp. 1220-1228
Author(s):  
S Dana ◽  
J J Wasmuth
Keyword(s):  
Human Chromosome ◽  
Mammalian Species ◽  
Chinese Hamster ◽  
Trna Synthetase ◽  
Gene Organization ◽  
Deletion Mapping ◽  
Chromosome 2 ◽  
Chromosome 5 ◽  
Human Chromosome 5 ◽  
Chinese Hamster Chromosome

Chinese hamster-human interspecific hybrid cells, which contain human chromosome 5 and express four genes linked on that chromosome, were subjected to selective conditions requiring them to retain one of the four linked genes, leuS (encoding leucyl-tRNA synthetase), but lose another, either emtB (encoding ribosomal protein S14) or chr. Cytogenetic and biochemical analyses of spontaneous segregants isolated by using these unique selective pressures have enabled us to determine the order and regional location of the leuS, hexB, emtB, and chr genes on human chromosome 5. These segregants arise primarily by terminal deletions of various portions of the long arm of chromosome 5. Our results indicate that the order of at least three of these genes is the same on human chromosome 5 and Chinese hamster chromosome 2. Thus, there appears to be extensive homology between Chinese hamster chromosome 2 and human chromosome 5, which represents an extreme example of the conservation of gene organization between very divergent mammalian species. In addition, these hybrids and selective conditions provide a very simple and quantitative means to assess the potency of various agents suspected of inducing gross chromosomal damage.

scholarly journals GENETIC ANALYSIS OF A MOUSE t COMPLEX LOCUS THAT IS HOMOLOGOUS TO A KIDNEY cDNA CLONE

Genetics ◽  
1986 ◽  
Vol 114 (3) ◽  
pp. 993-1006
Author(s):  
Elizabeth A Mann ◽  
Lee M Silver ◽  
Rosemary W Elliott
Keyword(s):  
Cdna Clone ◽  
Chinese Hamster ◽  
Chromosome 17 ◽  
Chromosome 4 ◽  
Wild Type ◽  
Hybrid Analysis ◽  
T Complex ◽  
Proximal Half ◽  
Length Polymorphisms ◽  
Complex Locus

ABSTRACT A mouse kidney cDNA clone, pMK174, identifies restriction fragment length polymorphisms (RFLPs) that map to two unlinked loci. One, designated D17Rp17, has been mapped near quaking, (qk), on chromosome 17 using three sets of recombinant inbred (RI) strains. A study of several t haplotypes resulted in the identification of t-specific alleles of D17Rp17 that map to the proximal half of the t complex. Neither t-specific nor wild-type D17Rp17 alleles are present in chromosomes carrying either the T Orleans (TtOrl) or the T hairpin tail (Thp) deletions. Comparison with other molecular markers indicates that pMK174 identifies a new proximal t complex locus, Rp17. The second locus identified by pMK174, termed D4Rp18, is tentatively assigned to chromosome 4 by mouse-Chinese hamster somatic cell hybrid analysis.

Assignment of genes encoding metallothioneins I and II to Chinese hamster chromosome 3: evidence for the role of chromosome rearrangement in gene amplification

1984 ◽  
Vol 4 (12) ◽  
pp. 2932-2936
Author(s):  
R L Stallings ◽  
A C Munk ◽  
J L Longmire ◽  
C E Hildebrand ◽  
B D Crawford
Keyword(s):  
Cell Lines ◽  
Chromosome Rearrangement ◽  
Cdna Probe ◽  
Chinese Hamster ◽  
Chinese Hamster Cell ◽  
Chromosome 3 ◽  
Chromosome 3P ◽  
Genes Encoding ◽  
Cytogenetic Analyses ◽  
Chinese Hamster Chromosome

Cadmium resistant (Cdr) variants with coordinately amplified metallothionein I and II (MTI and MTII) genes have been derived from both Chinese hamster ovary and near-euploid Chinese hamster cell lines. Cytogenetic analyses of Cdr variants consistently revealed breakage and rearrangement involving chromosome 3p. In situ hybridization with a Chinese hamster MT-encoding cDNA probe localized amplified MT gene sequences near the translocation breakpoint involving chromosome 3p. These observations suggested that both functionally related, isometallothionein loci are linked on Chinese hamster chromosome 3. Southern blot analyses of DNAs isolated from a panel of Chinese hamster X mouse somatic cell hybrids which segregate hamster chromosomes confirmed that both MTI and MTII are located on chromosome 3. We speculate that rearrangement of chromosome 3p could be causally involved with the amplification of MT genes in Cdr hamster cell lines.

scholarly journals Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5.

1982 ◽  
Vol 2 (10) ◽  
pp. 1220-1228 ◽  
Author(s):  
S Dana ◽  
J J Wasmuth
Keyword(s):  
Human Chromosome ◽  
Mammalian Species ◽  
Chinese Hamster ◽  
Trna Synthetase ◽  
Gene Organization ◽  
Deletion Mapping ◽  
Chromosome 2 ◽  
Chromosome 5 ◽  
Human Chromosome 5 ◽  
Chinese Hamster Chromosome

Chinese hamster-human interspecific hybrid cells, which contain human chromosome 5 and express four genes linked on that chromosome, were subjected to selective conditions requiring them to retain one of the four linked genes, leuS (encoding leucyl-tRNA synthetase), but lose another, either emtB (encoding ribosomal protein S14) or chr. Cytogenetic and biochemical analyses of spontaneous segregants isolated by using these unique selective pressures have enabled us to determine the order and regional location of the leuS, hexB, emtB, and chr genes on human chromosome 5. These segregants arise primarily by terminal deletions of various portions of the long arm of chromosome 5. Our results indicate that the order of at least three of these genes is the same on human chromosome 5 and Chinese hamster chromosome 2. Thus, there appears to be extensive homology between Chinese hamster chromosome 2 and human chromosome 5, which represents an extreme example of the conservation of gene organization between very divergent mammalian species. In addition, these hybrids and selective conditions provide a very simple and quantitative means to assess the potency of various agents suspected of inducing gross chromosomal damage.

Sign in / Sign up

Export Citation Format

Share Document