Cognitive Agents for Sense and Respond Logistics

Author(s):  
Kshanti Greene ◽  
David G. Cooper ◽  
Anna L. Buczak ◽  
Michael Czajkowski ◽  
Jeffrey L. Vagle ◽  
...  
Author(s):  
Ewart J. de Visser ◽  
Frank Krueger ◽  
Patrick McKnight ◽  
Steven Scheid ◽  
Melissa Smith ◽  
...  
Keyword(s):  

2019 ◽  
Author(s):  
Liem Viet Ngo ◽  
Tania Bucic ◽  
Ashish Sinha ◽  
Vinh Nhat Lu
Keyword(s):  

Cancers ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 350
Author(s):  
Julianty Frost ◽  
Mark Frost ◽  
Michael Batie ◽  
Hao Jiang ◽  
Sonia Rocha

Hypoxia—reduction in oxygen availability—plays key roles in both physiological and pathological processes. Given the importance of oxygen for cell and organism viability, mechanisms to sense and respond to hypoxia are in place. A variety of enzymes utilise molecular oxygen, but of particular importance to oxygen sensing are the 2-oxoglutarate (2-OG) dependent dioxygenases (2-OGDs). Of these, Prolyl-hydroxylases have long been recognised to control the levels and function of Hypoxia Inducible Factor (HIF), a master transcriptional regulator in hypoxia, via their hydroxylase activity. However, recent studies are revealing that dioxygenases are involved in almost all aspects of gene regulation, including chromatin organisation, transcription and translation. We highlight the relevance of HIF and 2-OGDs in the control of gene expression in response to hypoxia and their relevance to human biology and health.


BIOspektrum ◽  
2021 ◽  
Vol 27 (4) ◽  
pp. 385-389
Author(s):  
Kai Weissenbruch ◽  
Marc Hippler ◽  
Martin Bastmeyer

AbstractThe ability of cells to sense and respond to extracellular forces is critical for cellular and tissue homeostasis. Tension or compression act on our body ubiquitously and cells respond to such mechanical cues by producing intracellular forces on their own. In this article, we briefly highlight the cellular and physical basis driving these phenomena and discuss our recent technical advance to stimulate and monitor the cellular mechanoresponse on a molecular scale.


2011 ◽  
Vol 34 (2) ◽  
pp. 78-79 ◽  
Author(s):  
John Fox

AbstractMercier and Sperber (M&S) suggest that human reasoning is reflective and has evolved to support social interaction. Cognitive agents benefit from being able to reflect on their beliefs whether they are acting alone or socially. A formal framework for argumentation that has emerged from research on artificial cognitive systems that parallels M&S's proposals may shed light on mental processes that underpin social interactions.


2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Soumya Bhattacharjee ◽  
Kaushik Renganaath ◽  
Rajesh Mehrotra ◽  
Sandhya Mehrotra

The complexity and diversity of eukaryotic organisms are a feat of nature’s engineering. Pulling the strings of such an intricate machinery requires an even more masterful and crafty approach. Only the number and type of responses that they generate exceed the staggering proportions of environmental signals perceived and processed by eukaryotes. Hence, at first glance, the cell’s sparse stockpile of controlling factors does not seem remotely adequate to carry out this response. The question as to how eukaryotes sense and respond to environmental cues has no single answer. It is an amalgamation, an interplay between several processes, pathways, and factors—a combinatorial control. A short description of some of the most important elements that operate this entire conglomerate is given in this paper.


2015 ◽  
Vol 7 (12) ◽  
pp. 1611-1621 ◽  
Author(s):  
Kyle E. Broaders ◽  
Alec E. Cerchiari ◽  
Zev J. Gartner

Epithelia have the capacity to sense and respond to substrate topography through the coupling of tensions at the cell–cell, cell–substrate, and cell–medium interfaces.


2014 ◽  
Vol 1 (1) ◽  
Author(s):  
Markus RM Fiedler ◽  
Annett Lorenz ◽  
Benjamin M Nitsche ◽  
Cees AMJJ van den Hondel ◽  
Arthur FJ Ram ◽  
...  

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