Red-Emitting Upconverting Nanoparticles for Photodynamic Therapy in Cancer Cells Under Near-Infrared Excitation

Small ◽  
2012 ◽  
Vol 9 (11) ◽  
pp. 1929-1938 ◽  
Author(s):  
Gan Tian ◽  
Wenlu Ren ◽  
Liang Yan ◽  
Shan Jian ◽  
Zhanjun Gu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Near Infrared ◽  
Infrared Excitation

scholarly journals Upconversion: Red-Emitting Upconverting Nanoparticles for Photodynamic Therapy in Cancer Cells Under Near-Infrared Excitation (Small 11/2013)

Small ◽  
2013 ◽  
Vol 9 (11) ◽  
pp. 1928-1928 ◽  
Author(s):  
Gan Tian ◽  
Wenlu Ren ◽  
Liang Yan ◽  
Shan Jian ◽  
Zhanjun Gu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Near Infrared ◽  
Infrared Excitation

Photosensitizer coated upconversion nanoparticles for triggering reactive oxygen species under 980 nm near-infrared excitation

2019 ◽  
Vol 7 (46) ◽  
pp. 7306-7313 ◽  
Author(s):  
Jinhua Wu ◽  
Shanshan Du ◽  
Yuhua Wang
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Rare Earth ◽  
Near Infrared ◽  
Reactive Oxygen ◽  
Great Promise ◽  
Upconversion Nanoparticles ◽  
Oxygen Species ◽  
Infrared Excitation

Rare-earth-based upconversion nanotechnology has recently shown great promise for photodynamic therapy (PDT).

Efficient Upconverting Nanophosphors for Imaging and Photodynamic Therapy

2012 ◽  
Vol 1471 ◽  
Author(s):  
Brian G. Yust ◽  
Gangadharan Ajith Kumar ◽  
Lawrence C. Mimun ◽  
Dhiraj K. Sardar
Keyword(s):  
Photodynamic Therapy ◽  
Rare Earth ◽  
Biomedical Applications ◽  
Near Infrared ◽  
High Efficiency ◽  
Synthesis Method ◽  
Spectroscopic Properties ◽  
Sodium Potassium ◽  
Infrared Excitation ◽  
Upconverting Nanophosphors

ABSTRACTErbium-Ytterbium codoped nanophosphor systems are explored for high efficiency upconversion. The NIR to visible upconversion from 1550 nm and 980 nm excitation are of particular interest to us for biomedical applications such as imaging, sensing, and photodynamic therapy. Variations in synthesis method and rare earth concentration are carried out in sodium, potassium, and transition metal based phosphor materials. The spectroscopic properties of the material dry and in biologically appropriate solution are taken. After bioconjugation, these particles will be used in a mouse model to demonstrate that cancer imaging with a near-infrared excitation source is possible.

Amphiphilic copolymer coated upconversion nanoparticles for near-infrared light-triggered dual anticancer treatment

Nanoscale ◽  
2014 ◽  
Vol 6 (24) ◽  
pp. 14903-14910 ◽  
Author(s):  
Shun Yang ◽  
Najun Li ◽  
Zhuang Liu ◽  
Wenwei Sha ◽  
Dongyun Chen ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Controlled Release ◽  
Cancer Cells ◽  
Self Assembly ◽  
Near Infrared ◽  
Amphiphilic Copolymer ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Assembly Process ◽  
Anticancer Treatment

The light-triggered controlled release of anticancer drugs accompanied with NIR-responsive photodynamic therapy was performed via a self-assembly process. Under 980 nm laser, the cancer cells could be effectively inhibited by released drugs and singlet oxygen simultaneously.

Activatable photodynamic destruction of cancer cells by NIR dye/photosensitizer loaded liposomes

2015 ◽  
Vol 51 (16) ◽  
pp. 3340-3342 ◽  
Author(s):  
Ahu Yuan ◽  
Xiaolei Tang ◽  
Xuefeng Qiu ◽  
Ke Jiang ◽  
Jinhui Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Indocyanine Green ◽  
Cancer Cells ◽  
Near Infrared ◽  
Chlorin E6 ◽  
Nir Dye

The phototoxicity of Chlorin e6 (Ce6) for photodynamic therapy (PDT) was found to be effectively suppressed by indocyanine green (ICG), a near infrared (NIR) dye.

A Janus upconverting nanoplatform with biodegradability for glutathione depletion, near-infrared light induced photodynamic therapy and accelerated excretion

2020 ◽  
Vol 8 (40) ◽  
pp. 9251-9257
Author(s):  
Hang Zhou ◽  
Qunying Li ◽  
Xi Cheng ◽  
Chao Zhang ◽  
Jiawei Sun ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Near Infrared ◽  
Glutathione Depletion ◽  
Infrared Light ◽  
Oxygen Species ◽  
Tissue Penetration ◽  
Excitation Light ◽  
The Poor

The major limitations of photodynamic therapy (PDT) are the poor tissue penetration of excitation light and the neutralization of reactive oxygen species (ROS) generated by overexpressed glutathione (GSH) in cancer cells.

Sign in / Sign up

Export Citation Format

Share Document