In situ photocrosslinkable hyaluronic acid-based surgical glue with tunable mechanical properties and high adhesive strength

2018 ◽  
Vol 57 (4) ◽  
pp. 522-530 ◽  
Author(s):  
Ajeesh Chandrasekharan ◽  
Keum-Yong Seong ◽  
Sang-Gu Yim ◽  
Sodam Kim ◽  
Sungbaek Seo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Adhesive Strength ◽  
Tunable Mechanical Properties ◽  
High Adhesive Strength

3D Printing of an In Situ Grown MOF Hydrogel with Tunable Mechanical Properties

2020 ◽  
Vol 12 (29) ◽  
pp. 33267-33275 ◽  
Author(s):  
Wangqu Liu ◽  
Ozan Erol ◽  
David H. Gracias
Keyword(s):  
Mechanical Properties ◽  
3D Printing ◽  
Tunable Mechanical Properties

scholarly journals Design of Biomimetic Cell-Interactive Substrates Using Hyaluronic Acid Hydrogels with Tunable Mechanical Properties

2012 ◽  
Vol 13 (6) ◽  
pp. 1818-1827 ◽  
Author(s):  
Emilie Hachet ◽  
Hélène Van Den Berghe ◽  
Eric Bayma ◽  
Marc R. Block ◽  
Rachel Auzély-Velty
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Tunable Mechanical Properties

Designing crosslinked hyaluronic acid hydrogels with tunable mechanical properties for biomedical applications

2015 ◽  
Vol 132 (22) ◽  
pp. n/a-n/a ◽  
Author(s):  
Anahita Khanlari ◽  
Jason E. Schulteis ◽  
Tiffany C. Suekama ◽  
Michael S. Detamore ◽  
Stevin H. Gehrke
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Biomedical Applications ◽  
Tunable Mechanical Properties

scholarly journals Reversible Mechanical Regulation and Splicing Ability of Alginate-Based Gel Based on Photo-Responsiveness of Molecular-Level Conformation

Materials ◽  
2019 ◽  
Vol 12 (18) ◽  
pp. 2919 ◽  
Author(s):  
Ma ◽  
He ◽  
Wan ◽  
Xiang ◽  
Fan ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Molecular Conformation ◽  
Molecular Level ◽  
Irradiation Time ◽  
Covalent Bonds ◽  
Cavity Structure ◽  
New Strategy ◽  
Hollow Cavity ◽  
Tunable Mechanical Properties

In this study, benefiting from the sensitive molecular conformation transversion in azobenzene, a new strategy for fabricating alginate gels with the abilities of splicing and photo-responsive mechanical adjustment is reported. Firstly, a 4,4’-azobis(benzoylhydrazide) (Azo-hydrazide) linker was used to crosslink alginate physically via the electrostatic interaction between hydrazide groups and carboxyl groups. It was then shaped and transferred in situ to a chemically crosslinked gel via 450 nm light irradiation. Under the irradiation, the molecular conformation change of azobenzene in the linker was able to form covalent bonds at the crosslinking points of the gels. Furthermore, the reversible conformation transformation of azobenzene was able to induce the increase and decrease of the storage modulus under irradiation with 365 nm light and 450 nm light, respectively, while also providing gel-like mechanical properties, depending upon the irradiation time and given wavelength. Meanwhile, the results also indicated that active groups could contribute to the splicing ability of the gel and construct a hollow cavity structure. It is believed that this work could provide a versatile strategy for preparing photo-responsive gels with reversibly tunable mechanical properties.

In situ fabrication of a composite hydrogel with tunable mechanical properties for cartilage tissue engineering

2019 ◽  
Vol 7 (15) ◽  
pp. 2463-2473 ◽  
Author(s):  
Fenbo Ma ◽  
Yongmei Ge ◽  
Nian Liu ◽  
Xiangchao Pang ◽  
Xingyu Shen ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Composite Hydrogel ◽  
Cartilage Tissue ◽  
In Situ Fabrication ◽  
Tunable Mechanical Properties

A composite hydrogel with tunable mechanical properties has been fabricated and characterized in this study.

The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation

Biomaterials ◽  
2010 ◽  
Vol 31 (14) ◽  
pp. 3930-3940 ◽  
Author(s):  
Stephanie K. Seidlits ◽  
Zin Z. Khaing ◽  
Rebecca R. Petersen ◽  
Jonathan D. Nickels ◽  
Jennifer E. Vanscoy ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Tunable Mechanical Properties

Dynamics of Nanoparticle Chain Aggregates of Carbon Under Tension

2003 ◽  
Vol 778 ◽  
Author(s):  
Rajdip Bandyopadhyaya ◽  
Weizhi Rong ◽  
Yong J. Suh ◽  
Sheldon K. Friedlander
Keyword(s):  
Mechanical Properties ◽  
Carbon Black ◽  
Polymer Film ◽  
Elastic Behavior ◽  
Small Strains ◽  
Transmission Electron ◽  
Chain Aggregates ◽  
Nanoparticle Chains ◽  
Reinforcing Filler

AbstractCarbon black in the form of nanoparticle chains is used as a reinforcing filler in elastomers. However, the dynamics of the filler particles under tension and their role in the improvement of the mechanical properties of rubber are not well understood. We have studied experimentally the dynamics of isolated nanoparticle chain aggregates (NCAs) of carbon made by laser ablation, and also that of carbon black embedded in a polymer film. In situ studies of stretching and contraction of such chains in the transmission electron microscope (TEM) were conducted under different maximum values of strain. Stretching causes initially folded NCA to reorganize into a straight, taut configuration. Further stretching leads to either plastic deformation and breakage (at 37.4% strain) or to a partial elastic behavior of the chain at small strains (e.g. 2.3% strain). For all cases the chains were very flexible under tension. Similar reorientation and stretching was observed for carbon black chains embedded in a polymer film. Such flexible and elastic nature of NCAs point towards a possible mechanism of reinforcement of rubber by carbon black fillers.

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