scholarly journals Design of Biomimetic Cell-Interactive Substrates Using Hyaluronic Acid Hydrogels with Tunable Mechanical Properties

2012 ◽  
Vol 13 (6) ◽  
pp. 1818-1827 ◽  
Author(s):  
Emilie Hachet ◽  
Hélène Van Den Berghe ◽  
Eric Bayma ◽  
Marc R. Block ◽  
Rachel Auzély-Velty
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Tunable Mechanical Properties

Designing crosslinked hyaluronic acid hydrogels with tunable mechanical properties for biomedical applications

2015 ◽  
Vol 132 (22) ◽  
pp. n/a-n/a ◽  
Author(s):  
Anahita Khanlari ◽  
Jason E. Schulteis ◽  
Tiffany C. Suekama ◽  
Michael S. Detamore ◽  
Stevin H. Gehrke
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Biomedical Applications ◽  
Tunable Mechanical Properties

In situ photocrosslinkable hyaluronic acid-based surgical glue with tunable mechanical properties and high adhesive strength

2018 ◽  
Vol 57 (4) ◽  
pp. 522-530 ◽  
Author(s):  
Ajeesh Chandrasekharan ◽  
Keum-Yong Seong ◽  
Sang-Gu Yim ◽  
Sodam Kim ◽  
Sungbaek Seo ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Adhesive Strength ◽  
Tunable Mechanical Properties ◽  
High Adhesive Strength

The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation

Biomaterials ◽  
2010 ◽  
Vol 31 (14) ◽  
pp. 3930-3940 ◽  
Author(s):  
Stephanie K. Seidlits ◽  
Zin Z. Khaing ◽  
Rebecca R. Petersen ◽  
Jonathan D. Nickels ◽  
Jennifer E. Vanscoy ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Cell Differentiation ◽  
Progenitor Cell ◽  
Neural Progenitor Cell ◽  
Neural Progenitor ◽  
Tunable Mechanical Properties

scholarly journals 3D Printing of High Viscosity Reinforced Silicone Elastomers

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2239
Author(s):  
Nicholas Rodriguez ◽  
Samantha Ruelas ◽  
Jean-Baptiste Forien ◽  
Nikola Dudukovic ◽  
Josh DeOtte ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
High Performance ◽  
New Technologies ◽  
Three Dimensional ◽  
High Viscosity ◽  
Layer By Layer ◽  
Silicone Elastomers ◽  
Uv Curable ◽  
Octet Truss ◽  
Tunable Mechanical Properties

Recent advances in additive manufacturing, specifically direct ink writing (DIW) and ink-jetting, have enabled the production of elastomeric silicone parts with deterministic control over the structure, shape, and mechanical properties. These new technologies offer rapid prototyping advantages and find applications in various fields, including biomedical devices, prosthetics, metamaterials, and soft robotics. Stereolithography (SLA) is a complementary approach with the ability to print with finer features and potentially higher throughput. However, all high-performance silicone elastomers are composites of polysiloxane networks reinforced with particulate filler, and consequently, silicone resins tend to have high viscosities (gel- or paste-like), which complicates or completely inhibits the layer-by-layer recoating process central to most SLA technologies. Herein, the design and build of a digital light projection SLA printer suitable for handling high-viscosity resins is demonstrated. Further, a series of UV-curable silicone resins with thiol-ene crosslinking and reinforced by a combination of fumed silica and MQ resins are also described. The resulting silicone elastomers are shown to have tunable mechanical properties, with 100–350% elongation and ultimate tensile strength from 1 to 2.5 MPa. Three-dimensional printed features of 0.4 mm were achieved, and complexity is demonstrated by octet-truss lattices that display negative stiffness.

Biomimetic porous Mg with tunable mechanical properties and biodegradation rates for bone regeneration

2019 ◽  
Vol 84 ◽  
pp. 453-467 ◽  
Author(s):  
Min-Ho Kang ◽  
Hyun Lee ◽  
Tae-Sik Jang ◽  
Yun-Jeong Seong ◽  
Hyoun-Ee Kim ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Regeneration ◽  
Tunable Mechanical Properties

Plastic-like Hydrogels with Reversible Conversion of Elasticity and Plasticity and Tunable Mechanical Properties

2019 ◽  
Vol 11 (44) ◽  
pp. 41659-41667 ◽  
Author(s):  
Jinrong Wang ◽  
Zhuo Chen ◽  
Xueyan Li ◽  
Mingjie Liu ◽  
Ying Zhu ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tunable Mechanical Properties

3D magnetic printing of bio-inspired composites with tunable mechanical properties

2018 ◽  
Vol 53 (20) ◽  
pp. 14274-14286 ◽  
Author(s):  
Luquan Ren ◽  
Xueli Zhou ◽  
Qingping Liu ◽  
Yunhong Liang ◽  
Zhengyi Song ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tunable Mechanical Properties

MECHANICAL PROPERTIES CHANGE IN THE RAT XENOGRAFT MODEL TREATED BY MESENCHYMAL CELLS CULTURED IN AN HYALURONIC ACID-BASED HYDROGEL

2018 ◽  
Vol 18 (05) ◽  
pp. 1850047
Author(s):  
MUSTAPHA ZIDI ◽  
ERIC ALLAIRE
Keyword(s):  
Mechanical Properties ◽  
Hyaluronic Acid ◽  
Arterial Wall ◽  
Cellular Therapy ◽  
Xenograft Model ◽  
Strain Energy Function ◽  
Aortic Aneurysms ◽  
Large Strains ◽  
Abdominal Aortic ◽  
Wall Stiffness

This study investigated the efficiency of a cellular therapy with mesenchymal stem cells (MSCs) cultured in an hyaluronic acid-based hydrogel on growth of abdominal aortic aneurysms (AAA) obtained in the rat xenograft model. The experimental model was devoted to create an AAA at D14 after grafting of a decellularized abdominal aorta obtained from guinea pigs before being transplanted into rats. At D21, geometrical measurements as radius and length of AAA were performed on untreated ([Formula: see text]) and treated ([Formula: see text]) arteries. When compared to different cases, it was shown that the proposed cellular treatment significantly reduced the expansion of radius and length of AAA. Furthermore, to explore the mechanical properties change of the arterial wall, an inverse finite element method was performed where AAA is represented by an elliptical geometry with varying thicknesses. To identify the material parameters, the AAA tissue was assumed to behave isochoric and isotropic undergoing large strains and described by the Yeoh’s strain energy function. Although limitations exist in this study such as the time of the experimental protocol, the isotropic behavior law of the AAA wall and the axisymmetric geometry of the artery, the results revealed that arterial wall stiffness change and the maximum effective stress decreased during expansion of AAA when cellular treatment is applied.

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