peptide rgd
Recently Published Documents


TOTAL DOCUMENTS

16
(FIVE YEARS 0)

H-INDEX

9
(FIVE YEARS 0)

2020 ◽  
Vol 21 (2) ◽  
Author(s):  
Mengyue Liu ◽  
Xuan Jiang ◽  
Chao Fu ◽  
Ruili Zhao ◽  
Tianming Jin ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 24 ◽  
Author(s):  
McKay Cavanaugh ◽  
Elena Silantyeva ◽  
Galina Pylypiv Koh ◽  
Elham Malekzadeh ◽  
William D. Lanzinger ◽  
...  

Nerve injuries requiring surgery are a significant problem without good clinical alternatives to the autograft. Tissue engineering strategies are critically needed to provide an alternative. In this study, we utilized aligned nanofibers that were click-modified with the bioactive peptide RGD for rat sciatic nerve repair. Empty conduits or conduits filled with either non-functionalized aligned nanofibers or RGD-functionalized aligned nanofibers were used to repair a 13 mm gap in the rat sciatic nerve of animals for six weeks. The aligned nanofibers encouraged cell infiltration and nerve repair as shown by histological analysis. RGD-functionalized nanofibers reduced muscle atrophy. During the six weeks of recovery, the animals were subjected to motor and sensory tests. Sensory recovery was improved in the RGD-functionalized nanofiber group by week 4, while other groups needed six weeks to show improvement after injury. Thus, the use of functionalized nanofibers provides cues that aid in in vivo nerve repair and should be considered as a future repair strategy.


2016 ◽  
Vol 64 (12) ◽  
pp. 1726-1738 ◽  
Author(s):  
Kazuhiro Higuchi ◽  
Hideki Hikita ◽  
Asumi Murayama ◽  
Daichi Yuri ◽  
Natsu Kobayakawa ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (48) ◽  
pp. 42109-42119 ◽  
Author(s):  
Gang Pan ◽  
Yi-jie Bao ◽  
Jie Xu ◽  
Tao Liu ◽  
Cheng Liu ◽  
...  

We report on the fabrication of a multifunctional polymeric prodrug covalently linked with an anticancer drug (bufalin, BUF) and tumor-targeting peptide (RGD) and investigate its anticancer performance against colon cancer in mice.


2013 ◽  
Vol 9 (2) ◽  
pp. 5040-5051 ◽  
Author(s):  
E.J. Tocce ◽  
S.J. Liliensiek ◽  
A.H. Broderick ◽  
Y. Jiang ◽  
K.C. Murphy ◽  
...  

Langmuir ◽  
2012 ◽  
Vol 28 (5) ◽  
pp. 2799-2811 ◽  
Author(s):  
Chunya Wu ◽  
Adam A. Skelton ◽  
Mingjun Chen ◽  
Lukas Vlček ◽  
Peter T. Cummings
Keyword(s):  

2011 ◽  
Vol 115 (45) ◽  
pp. 22375-22386 ◽  
Author(s):  
Chunya Wu ◽  
Adam A. Skelton ◽  
Mingjun Chen ◽  
Lukas Vlček ◽  
Peter T. Cummings

Amino Acids ◽  
2010 ◽  
Vol 41 (5) ◽  
pp. 1059-1070 ◽  
Author(s):  
Jiyun Shi ◽  
Young-Seung Kim ◽  
Sudipta Chakraborty ◽  
Yang Zhou ◽  
Fan Wang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document