Difference of Human Kinetic Frequency on Mattress by Fourier Transform

Background: The new science which examines the life in energy and frequency by quantum life science is noticed. Mattresses of various concepts are used on beds which are always installed in hospitals and facilities. It has been reported that human beings constantly roll over and vibrate in minute detail against the gravity, even at night, and it can be said that motion dynamics are necessary life activity as long as human beings live as living organisms. Therefore, it may be important as life observation to analyze not only physical aspects such as the body, bed and mattress, but also physical aspects such as kinematic and dynamic energy, force, speed and time, when examining human health and the medical treatment environment for life. However, few studies have examined the kinematic effects and differences of mattresses. The quality of a mattress affects the health of the patient or user using it in the short and long term. The choice of mattress and its cost are also important factors in hospital and facility management. In this study, we examined the differences of movement frequencies that human produce on the different mattresses.Methods: Healthy volunteers were recruited by a snowball sampling. The movement from the supine position to the sitting position on Air-based Mattress, Middle Hardees Urethane Mattress, and High hardness Urethane Mattress were repeated for three times. The three procedure was analyzed with a 12 segments model using a 3D motion analysis Move Tr 3D (Library©) under the 4 CCD cameras. The analysis of the velocity and acceleration data were performed by Fourier Transform (IDL). The sensory test for sleeping comfort revised was investigated after the third time. The mathematical expressions to be physically examined from the data of this study were also examined.Results: Five healthy volunteers (Medium age 31 years, Female) who received written consent to the study were investigated. Air mattress took longer time to be head up than both urethane mattresses. The velocity changes of both Medium Hardness and High Hardness Urethan mattresses were similar. Air mattress had a high frequency in the vicinity around 3 sec after the movement beginning. There was no difference in the frequency of the head acceleration between two mattresses and the high frequency was strong until coming to the head up.Conclusion: The difference in the human kinetic frequency using Fourier Transform suggests that there is a difference in the frequency produced by humans moving on different mattresses.

Integrating physiologically based kinetic (PBK) and Monte Carlo modelling to predict inter-individual and inter-ethnic variation in bioactivation and liver toxicity of lasiocarpine

The aim of the present study was to predict the effect of inter-individual and inter-ethnic human kinetic variation on the sensitivity towards acute liver toxicity of lasiocarpine in the Chinese and the Caucasian population, and to derive chemical specific adjustment factors (CSAFs) by integrating variation in the in vitro kinetic constants Vmax and Km, physiologically based kinetic (PBK) modelling and Monte Carlo simulation. CSAFs were derived covering the 90th and 99th percentile of the population distribution of pyrrole glutathione adduct (7-GS-DHP) formation, reflecting bioactivation. The results revealed that in the Chinese population, as compared to the Caucasian population, the predicted 7-GS-DHP formation at the geometric mean, the 90th and the 99th percentile were 2.1-, 3.3- and 4.3-fold lower respectively. The CSAFs obtained using the 99th percentile values were 8.3, 17.0 and 19.5 in the Chinese, the Caucasian population and the two populations combined, respectively, while the CSAFs were generally 3.0-fold lower at the 90th percentile. These results indicate that when considering the formation of 7-GS-DHP the Caucasian population may be more sensitive towards acute liver toxicity of lasiocarpine, and further point out that the default safety factor of 3.16 for inter-individual human kinetic differences may not be sufficiently protective. Altogether, the results obtained demonstrate that integrating PBK modelling with Monte Carlo simulations using human in vitro data is a powerful strategy to quantify inter-individual variations in kinetics, and can be used to refine the human risk assessment of pyrrolizidine alkaloids.

A Socio-Academic Approach in Providing Renewable Energy Sources: Experiences of Mechanical Engineering Department, Mapua Institute of Technology

Mapua Institute of Technology has been constantly engaged in providing free, renewable energy to rural and under privileged communities. Guided by the mission and vision of the School of Mechanical and Manufacturing Engineering Department and of the Office of Social Orientation and Community Involvement, the school had implemented several renewable energy activities. This paper showcases 8 different projects — 6 hydropower plant projects, 1 human kinetic harvesting demonstration facility, and 1 wind turbine project. In this paper, implemented projects are presented briefly with emphasis on the different locations, local cultural settings and different experiences encountered. It will also share how students have changed from being participants to autonomous implementers of renewable energy projects for communities.