Different spectrophotometric methods manipulating ratio spectra for the assay of hydrocortisone acetate and clioquinol in their topical preparation

Simple and precise spectrophotometric methods for quantitative assay of a mixture of hydrocortisone acetate (HCA) and clioquinol (CL) were developed and validated through different mathematical manipulation pathways. The developed methods utilized ratio spectra for resolving binary mixtures including absorbance subtraction, ratio subtraction coupled with spectrum subtraction, constant multiplication, constant value, and derivative ratio. The proposed methods were proved to be specific by analysing the laboratory-prepared mixtures and were applied for the assay of topical preparation successfully. The methods were validated using ICH guidelines where accuracy, repeatability and intermediate precision were within the acceptable limits. The linearity range was found to be 2-22 for HCA and 1.5-7 µg/mL for CL in all proposed methods and 2-7 µg/mL for HCA and CL in absorbance subtraction method through using a unified regression equation. The findings were statistically evaluated with respect to the official and reported methods, demonstrating that there was no significant difference.

Exploring Multi-Level Composition and Efficient MCM Schemes for an Energy-Efficient Wavelet Haar Architecture

This work explores multi-level fixed-point Haar transform compositions combined with MCM (multiple constant multiplication) schemes for an energy-efficient hardware architecture. We investigate a set of six lower-level Haar transforms for composing a Haar-9 architecture. The multiple-level Haar transforms use as a base M=1, M=2, and M=3 resolution levels. The processing module (PM) of the Haar explores efficient MCM schemes. The architectures were described in VHDL and synthesized employing the ST 65nm CMOS cell library. The results show that Haar-II architecture presents the lower circuit area results since this architecture requires fewer arithmetic operators. However, the most energy-efficient Haar-9 hardware architecture employs a combination of two M=2 with five M=1 blocks with a efficient MCM architecture reduced to only two arithmetic operators.

High Speed FIR Filter Using Radix-2r Multiplier and Its Application for Denoising EOG Signal

In this paper, a modified finite impulse response (FIR) filter design has been proposed for the denoising bio-electrical signals like Electrooculography(EOG). The proposed filter architecture uses modified multiplier block, which is implemented using modified Radix-[Formula: see text] arithmetic-based representation for minimizing the multiple constant multiplication and conventional ripple carry adders are replaced with [Formula: see text] compressors. This proposed architecture is implemented by using Radix-[Formula: see text]-based multiplier and [Formula: see text] compressor architectures for achieving better improvement in the critical path delay. The Radix-[Formula: see text]-based arithmetic bit recording is used in order to reduce the design complexity of the multiplication. The proposed architecture significantly reduced the delay when compared to existing and conventional architectures.

Card-based Cryptography with Dihedral Symmetry

It is known that secure computation can be done by using a deck of physical cards. This area is called card-based cryptography. Shinagawa et al. (in: Provable security—9th international conference, ProvSec 2015, Kanazawa, Japan, 2015) proposed regular n-sided polygon cards that enable to compute functions over $${\mathbb {Z}}/n{\mathbb {Z}}$$ Z / n Z . In particular, they designed efficient protocols for linear functions (e.g. addition and constant multiplication) over $${\mathbb {Z}}/n{\mathbb {Z}}$$ Z / n Z . Here, efficiency is measured by the number of cards used in the protocol. In this paper, we propose a new type of cards, dihedral cards, as a natural generalization of regular polygon cards. Based on them, we construct efficient protocols for various interesting functions such as carry of addition, equality, and greater-than, whose efficient construction has not been known before. Beside this, we introduce a new protocol framework that captures a wide class of card types including binary cards, regular polygon cards, dihedral cards, and so on.

THEATER AND THEATRICALITY IN THEIR RELATION TO HISTORY AND THE ARTS IN THE NOVELS OF VLADIMIR SHAROV

Vladimir Sharov (1952–2018), a distinguished contemporary Russian writer, published nine quasi historical novels. Each of his novels suggests a different semi-fantastical version of Russian history that is locked into continuing cycles or - to use Sharov’s preferred word - “rehearsals” of violence. Theater and performance are a recurring theme in Sharov’s prose. In Before and During [До и во время], one of the main characters is Alexander Scriabin. In The Rehearsals [Репетиции] Patriarch Nikon orders a play – a mystery-play about Easter — in which the amateur peasant actors are assigned roles from the Bible and replay these roles for generations. In Should Not I Spare [Мне ли не пожалеть], the opening section shows characters participating in Chekhov’s plays, and the main part of the narration tells the story of staging an oratorio. In the last two novels, several of the protagonists are theater directors. This article argues that for Sharov, theater is an apt metaphor for history and a basic ontological principle, because theater is an experience that can be documented but is never reproduced in exactly the same form. The article examines how Sharov brings out the power of the playwright, director, and actor to implement multiple and different scripts and life stories. Life and art in his works imitate each other through a constant multiplication of versions or rehearsals - “rehearsals” in its expanded sense as reinterpretations, revisions, rewritings, and continuations.

Phenomenological Aspects on Life-World and Technization

This chapter discusses Hans Blumenberg's first extensive discussion of the concept of the life-world, “Phenomenological Aspects on Life-World and Technization” (1963). The problem of technology is such a characteristic element of modern, contemporary thought, even though the problem of technology has not yet been clearly distinguished from the problems of technology. The century or so of what called itself philosophy of technology has produced a sense of obviousness of what in the case of technology was “the thing itself” — a sense that is already highly suspicious. According to Ernst Kapp, “all of human history, upon close scrutiny, ultimately resolves into the history of the invention of better tools.” Correspondingly, the term “technology” evokes a colorful series of images: devices, vehicles, propulsion motors, storage units, manual and automatic instruments, and so forth — in short, a universe of things that are at work all around us, whose complete classification has often been attempted to little success, whose unifying factor, which the concept “technology” signifies, seems impossible to grasp, and which is therefore rendered unquestionable in a nominalistic way. With the appropriate conceptual frugality, “technization” is then to be understood as the constant multiplication and condensation of this thing-world.