THE HEALTH STATUS OF NEWBORNS FROM MOTHERS WITH CHRONIC SIMPLE BRONCHITIS IN REMISSION AND RISK OF MISCARRIAGE

The state of health of 100 full-term newborns from mothers with uncomplicated course of pregnancy and with chronic simple bronchitis in remission was studied. The first group consisted of 30 newborns from mothers with physiological pregnancy. The second group consisted of 38 children of a similar age from mothers who were diagnosed with simple chronic bronchitis without exacerbation in the period of gestation. The third group was represented by 32 newborns with antenatal history, burdened with chronic simple bronchitis in remission and the threat of miscarriage in their mothers in the second trimester of pregnancy. It was shown that in children of the third group, in comparison with the second group, there was a lower score on the Apgar scale at 5th minute (7.7±0.14 and 8.1±0.12 points, respectively, p<0.05); cerebral ischemia of moderate severity (n=7 and n=1, respectively, p<0.05) and vesiculosis (n=8 and n=1, respectively, p<0.05) were registered oftener. Only the third group of newborns showed signs of respiratory distress syndrome of moderate (n=2) and severe (n=2) degree, as well as aspiration of amniotic fluid (n=2). This indicates the role of chronic simple bronchitis in remission, associated with the threat of miscarriage in the second trimester of gestation, and in disturbance of delivery of oxygen and metabolites to the intrauterine patient, as well as in changing the conditions of antenatal development of its central nervous and respiratory systems.

Influence of the condition of antenatal development on the content of immunoglobulins in the blood of newborns

Studied IgG, IgA and IgM in 103 newborns up to the 12th day of life. In children whose mothers have suffered from pregnancy toxicosis, IgG and Dovppen IgA and IgM are reduced. Immunological changes in late toxicosis in pregnant women for the presence of additional antigenic stimulation of the fetus.