scholarly journals Autophagy Plays a Critical Role in Insulin Resistance- Mediated Chemoresistance in Hepatocellular Carcinoma Cells by Regulating the ER Stress

2018 ◽  
Vol 9 (23) ◽  
pp. 4314-4324 ◽  
Author(s):  
Linjing Li ◽  
Xinyue Liu ◽  
Liye Zhou ◽  
Wei Wang ◽  
Zhuan Liu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Insulin Resistance ◽  
Er Stress ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress

2015 ◽  
Vol 466 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Hyun Kook Cho ◽  
So Young Kim ◽  
Yi Yi Kyaw ◽  
Aye Aye Win ◽  
Seung-Hoi Koo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Transcription Factor ◽  
Er Stress ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx protein is encoded by HBV and plays a critical role in hepatocarcinogenesis. In the present study we show that HBx activates the expression of the CREBH transcription factor and interacts with the activated CREBH. CREBH activation by HBx may result in cell proliferation.

scholarly journals Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress

2019 ◽  
Vol 10 ◽  
Author(s):  
Qianqian Zhang ◽  
Weiqian Chen ◽  
Xiuling Lv ◽  
Qiaoyou Weng ◽  
Minjiang Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Er Stress ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

scholarly journals Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR

Oncotarget ◽  
2017 ◽  
Vol 8 (54) ◽  
pp. 93039-93050 ◽  
Author(s):  
Bo Ren ◽  
Hui Liu ◽  
Hang Gao ◽  
Shutong Liu ◽  
Zehui Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Er Stress ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

scholarly journals Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity

2020 ◽  
Vol 8 (5) ◽  
pp. 1316-1328 ◽  
Author(s):  
Kalpana Mandal ◽  
Ze Gong ◽  
Alexis Rylander ◽  
Vivek B. Shenoy ◽  
Paul A. Janmey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Morphology ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Substrate Interaction ◽  
Cell Substrate

Viscosity plays a critical role in cell morphology, dynamics and cell-substrate interaction.

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