scholarly journals Alpha fetoprotein plays a critical role in promoting metastasis of hepatocellular carcinoma cells

2016 ◽  
Vol 20 (3) ◽  
pp. 549-558 ◽  
Author(s):  
Yan Lu ◽  
Mingyue Zhu ◽  
Wei Li ◽  
Bo Lin ◽  
Xu Dong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Alpha Fetoprotein ◽  
Hepatocellular Carcinoma Cells

HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress

2015 ◽  
Vol 466 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Hyun Kook Cho ◽  
So Young Kim ◽  
Yi Yi Kyaw ◽  
Aye Aye Win ◽  
Seung-Hoi Koo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Transcription Factor ◽  
Er Stress ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx protein is encoded by HBV and plays a critical role in hepatocarcinogenesis. In the present study we show that HBx activates the expression of the CREBH transcription factor and interacts with the activated CREBH. CREBH activation by HBx may result in cell proliferation.

scholarly journals Opposite responses of normal hepatocytes and hepatocellular carcinoma cells to substrate viscoelasticity

2020 ◽  
Vol 8 (5) ◽  
pp. 1316-1328 ◽  
Author(s):  
Kalpana Mandal ◽  
Ze Gong ◽  
Alexis Rylander ◽  
Vivek B. Shenoy ◽  
Paul A. Janmey
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Morphology ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Substrate Interaction ◽  
Cell Substrate

Viscosity plays a critical role in cell morphology, dynamics and cell-substrate interaction.

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