scholarly journals Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress

2019 ◽  
Vol 10 ◽  
Author(s):  
Qianqian Zhang ◽  
Weiqian Chen ◽  
Xiuling Lv ◽  
Qiaoyou Weng ◽  
Minjiang Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Er Stress ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

scholarly journals Celastrol induces apoptosis in hepatocellular carcinoma cells via targeting ER-stress/UPR

Oncotarget ◽  
2017 ◽  
Vol 8 (54) ◽  
pp. 93039-93050 ◽  
Author(s):  
Bo Ren ◽  
Hui Liu ◽  
Hang Gao ◽  
Shutong Liu ◽  
Zehui Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Er Stress ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress

2015 ◽  
Vol 466 (1) ◽  
pp. 115-121 ◽  
Author(s):  
Hyun Kook Cho ◽  
So Young Kim ◽  
Yi Yi Kyaw ◽  
Aye Aye Win ◽  
Seung-Hoi Koo ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Proliferation ◽  
Transcription Factor ◽  
Er Stress ◽  
Critical Role ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

HBx protein is encoded by HBV and plays a critical role in hepatocarcinogenesis. In the present study we show that HBx activates the expression of the CREBH transcription factor and interacts with the activated CREBH. CREBH activation by HBx may result in cell proliferation.

scholarly journals Safranal induces DNA double-strand breakage and ER-stress-mediated cell death in hepatocellular carcinoma cells

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Ala’a Al-Hrout ◽  
Amphun Chaiboonchoe ◽  
Basel Khraiwesh ◽  
Chandraprabha Murali ◽  
Badriya Baig ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Death ◽  
Er Stress ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Strand Breakage
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